Patents by Inventor Linda Hanley-Bowdoin

Linda Hanley-Bowdoin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEPTIDE APTAMERS THAT BIND TO THE REP PROTEINS OF SSDNA VIRUSES
    Publication number: 20150329595
    Abstract: Polypeptides and fusion proteins that bind to eukaryotic viruses, in particular, eukaryotic single-stranded DNA (ssDNA) viruses are provided. The polypeptides and fusion proteins bind to the replication initiation proteins (Rep) of ssDNA viruses and optionally inhibit viral replication and/or viral infection. The virus can be a plant pathogen or animal pathogen. Consensus sequences used to identify polypeptides that bind to eukaryotic viruses are also provided.
    Type: Application
    Filed: August 6, 2015
    Publication date: November 19, 2015
    Inventors: Linda Hanley-Bowdoin, Luisa` Lopez-Ochoa
  • Peptide aptamers that bind to the rep proteins of ssDNA viruses
    Patent number: 9102705
    Abstract: Polypeptides and fusion proteins that bind to eukaryotic viruses, in particular, eukaryotic single-stranded DNA (ssDNA) viruses are provided. The polypeptides and fusion proteins bind to the replication initiation proteins (Rep) of ssDNA viruses and optionally inhibit viral replication and/or viral infection. The virus can be a plant pathogen or animal pathogen. Consensus sequences used to identify polypeptides that bind to eukaryotic viruses are also provided.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: August 11, 2015
    Assignee: North Carolina State University
    Inventors: Linda Hanley-Bowdoin, Luisa Lopez-Ochoa
  • Peptide Aptamers that Bind to the Rep Proteins of ssDNA Viruses
    Publication number: 20120220519
    Abstract: Polypeptides and fusion proteins that bind to eukaryotic viruses, in particular, eukaryotic single-stranded DNA (ssDNA) viruses are provided. The polypeptides and fusion proteins bind to the replication initiation proteins (Rep) of ssDNA viruses and optionally inhibit viral replication and/or viral infection. The virus can be a plant pathogen or animal pathogen. Consensus sequences used to identify polypeptides that bind to eukaryotic viruses are also provided.
    Type: Application
    Filed: April 2, 2012
    Publication date: August 30, 2012
    Inventors: Linda Hanley-Bowdoin, Luisa Lopez-Ochoa
  • Peptide aptamers that bind to the rep proteins of ssDNA viruses
    Patent number: 8168748
    Abstract: Polypeptides and fusion proteins that bind to eukaryotic viruses, in particular, eukaryotic single-stranded DNA (ssDNA) viruses are provided. The polypeptides and fusion proteins bind to the replication initiation proteins (Rep) of ssDNA viruses and optionally inhibit viral replication and/or viral infection. The virus can be a plant pathogen or animal pathogen. Consensus sequences used to identify polypeptides that bind to eukaryotic viruses are also provided.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: May 1, 2012
    Assignee: North Carolina State University
    Inventors: Linda Hanley-Bowdoin, Luisa Lopez-Ochoa
  • Geminivirus resistant transgenic plants
    Patent number: 8039688
    Abstract: Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. In addition, methods of making the transgenic plants of the present invention are included. The transgenic plants express a mutant AL1/C1 geminivirus protein, which increases resistance to infection by at least one geminivirus, compared to a non-transformed control plant.
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: October 18, 2011
    Assignees: North Carolina State University, The Regents of the University of California
    Inventors: Linda Hanley-Bowdoin, Beverly Orozco, Wilhelm Gruissem
  • GEMINIVIRUS RESISTANT TRANSGENIC PLANTS
    Publication number: 20090229013
    Abstract: Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. The transgenic plants express a mutant AL1/C1 geminivirus protein, which increases resistance to infection by at least one geminivirus, compared to a non-transformed control plant.
    Type: Application
    Filed: April 30, 2009
    Publication date: September 10, 2009
    Applicant: North Carolina State University
    Inventors: Linda Hanley-Bowdoin, Beverly Orozco, Wilhelm Gruissem
  • Peptide Aptamers That Bind to the Rep Proteins of Ssdna Viruses
    Publication number: 20080289065
    Abstract: Polypeptides and fusion proteins that bind to eukaryotic viruses, in particular, eukaryotic single-stranded DNA (ssDNA) viruses are provided. The polypeptides and fusion proteins bind to the replication initiation proteins (Rep) of ssDNA viruses and optionally inhibit viral replication and/or viral infection. The virus can be a plant pathogen or animal pathogen. Consensus sequences used to identify polypeptides that bind to eukaryotic viruses are also provided.
    Type: Application
    Filed: August 4, 2006
    Publication date: November 20, 2008
    Inventors: Linda Hanley-Bowdoin, Luisa Lopez-Ochoa
  • Geminivirus Resistant Transgenic Plants
    Publication number: 20080134359
    Abstract: Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. The transgenic plants express a mutant AL1/C1 geminivirus protein, which increases resistance to infection by at least one geminivirus, compared to a non-transformed control plant.
    Type: Application
    Filed: November 7, 2007
    Publication date: June 5, 2008
    Applicant: North Carolina State University
    Inventors: Linda Hanley-Bowdoin, Beverly Orozco, Wilhelm Gruissem
  • Geminivirus resistant transgenic plants
    Publication number: 20040205843
    Abstract: Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. The transgenic plants express a mutant AL1/C1 geminivirus protein, which increases resistance to infection by at least one geminivirus, compared to a non-transformed control plant.
    Type: Application
    Filed: August 4, 2003
    Publication date: October 14, 2004
    Inventors: Linda Hanley-Bowdoin, Beverly Orozco, Wilhelm Gruissem
  • Geminivirus resistant transgenic plants
    Patent number: 6800793
    Abstract: Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. The transgenic plants express a mutant AL1/C1 geminivirus protein, which increases resistance to infection by at least one geminivirus, compared to a non-transformed control plant.
    Type: Grant
    Filed: April 9, 1999
    Date of Patent: October 5, 2004
    Assignees: North Carolina State University, Regents of the University of California
    Inventors: Linda Hanley-Bowdoin, Beverly M. Orozco, Ling-Jie Kong, Wilhelm Gruissem
  • Geminivirus resistant transgenic plants expressing a mutant geminivirus AL3/C3 coding sequence
    Patent number: 6747188
    Abstract: Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. The transgenic plants express a mutant AL3/C3 geminivirus protein, which increases resistance to infection by at least one geminivirus, compared to a non-transformed control plant.
    Type: Grant
    Filed: October 1, 1998
    Date of Patent: June 8, 2004
    Assignee: North Carolina State University
    Inventors: Linda Hanley-Bowdoin, Sharon Settlage
  • Geminivirus resistant transgenic plants
    Publication number: 20030200562
    Abstract: Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. The transgenic plants express a mutant AL3/C3 geminivirus protein, which increases resistance to infection by at least one geminivirus, compared to a non-transformed control plant.
    Type: Application
    Filed: June 19, 2003
    Publication date: October 23, 2003
    Inventors: Linda Hanley-Bowdoin, Sharon Settlage
  • GEMINIVIRUS RESISTANT TRANSGENIC PLANTS
    Publication number: 20020138867
    Abstract: Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. The transgenic plants express a mutant AL1/C1 geminivirus protein, which increases resistance to infection by at least one geminivirus, compared to a non-transformed control plant.
    Type: Application
    Filed: April 9, 1999
    Publication date: September 26, 2002
    Inventors: LINDA HANLEY-BOWDOIN, BEVERLY M. OROZCO, LING-JIE KONG, WILHELM GRUISSEM
  • GEMINIVIRUS RESISTANT TRANSGENIC PLANTS
    Publication number: 20020073442
    Abstract: Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. The transgenic plants express a mutant AL3/C3 geminivirus protein, which increases resistance to infection by at least one geminivirus, compared to a non-transformed control plant.
    Type: Application
    Filed: October 1, 1998
    Publication date: June 13, 2002
    Applicant: North Carolina State University
    Inventors: LINDA HANLEY-BOWDOIN, SHARON SETTLAGE