Patents by Inventor Linda W. LANGMAN

Linda W. LANGMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for isolating pancreatic islets
    Patent number: 11590501
    Abstract: A microfluidic device can include an upstream passage, a sample passage, a bifurcating passage, and a combining passage. The upstream passage can be configured to provide a focusing stream. The sample passage can be configured to provide a sample stream. The bifurcating passage can include a specified bifurcating flow resistance. The combining passage can be configured to create a combined stream from the focusing stream and the sample stream, where the focusing stream can direct the sample stream away from the upstream passage and toward the bifurcating passage. A first portion of the combined stream can be discharged through the bifurcating passage. The main discharge can be configured to discharge a second portion of the combined stream. The main discharge can include a main discharge resistance that is selectable to vary the main discharge resistance relative to the bifurcating flow resistance.
    Type: Grant
    Filed: August 26, 2021
    Date of Patent: February 28, 2023
    Assignee: University of Virginia Patent Foundation
    Inventors: Nathan Swami, Walter Varhue, Linda W. Langman, Kenneth Brayman, Shayn Peirce-Cottler
  • SYSTEMS FOR ISOLATING AND TRANSPLANTING PANCREATIC ISLETS
    Publication number: 20220048030
    Abstract: A microfluidic device can include an upstream passage, a sample passage, a bifurcating passage, and a combining passage. The upstream passage can be configured to provide a focusing stream. The sample passage can be configured to provide a sample stream. The bifurcating passage can include a specified bifurcating flow resistance. The combining passage can be configured to create a combined stream from the focusing stream and the sample stream, where the focusing stream can direct the sample stream away from the upstream passage and toward the bifurcating passage. A first portion of the combined stream can be discharged through the bifurcating passage. The main discharge can be configured to discharge a second portion of the combined stream. The main discharge can include a main discharge resistance that is selectable to vary the main discharge resistance relative to the bifurcating flow resistance.
    Type: Application
    Filed: August 26, 2021
    Publication date: February 17, 2022
    Inventors: Nathan Swami, Walter Varhue, Linda W. Langman, Kenneth Brayman, Shayn Peirce-Cottler
  • SYSTEMS FOR ISOLATING AND TRANSPLANTING PANCREATIC ISLETS
    Publication number: 20200353469
    Abstract: A microfluidic device can include an upstream passage, a sample passage, a bifurcating passage, and a combining passage. The upstream passage can be configured to provide a focusing stream. The sample passage can be configured to provide a sample stream. The bifurcating passage can include a specified bifurcating flow resistance. The combining passage can be configured to create a combined stream from the focusing stream and the sample stream, where the focusing stream can direct the sample stream away from the upstream passage and toward the bifurcating passage. A first portion of the combined stream can be discharged through the bifurcating passage. The main discharge can be configured to discharge a second portion of the combined stream. The main discharge can include a main discharge resistance that is selectable to vary the main discharge resistance relative to the bifurcating flow resistance.
    Type: Application
    Filed: April 20, 2017
    Publication date: November 12, 2020
    Applicant: University of Virginia Patent Foundation
    Inventors: Nathan SWAMI, Waiter VARHUE, Linda W. LANGMAN, Kenneth BRAYMAN, Shayn PEIRCE-COTTLER