Patents by Inventor Lindsay S. Machan
Lindsay S. Machan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9751056Abstract: A movable mixing disc may be utilized in connection with a syringe. The mixing disc may comprise a hole which may be covered by a fine screen or coupled to a porous member, allowing only certain elements of a solution to pass through the mixing disc. Actuation of a plunger of the syringe may cause liquid to emerge from the mixing disc hole as a high velocity jet or other turbulent flow, stirring up any settled particles on a distal side of the mixing disc. As the ejection continues, the mixing disc may be pushed forward by the plunger in order to eliminate any unused volume. Also, the mixing disc may be moved forward by virtue of a pressure difference created by a pressure drop across the mixing disc, such as a pressure drop created as the plunger is displaced to induce fluid flow across the mixing disc.Type: GrantFiled: May 21, 2014Date of Patent: September 5, 2017Assignees: Merit Medical Systems, Inc., IKOMED Technologies, Inc.Inventors: Gregory R. McArthur, Lindsay S. Machan, Daniel Gelbart
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Publication number: 20150094593Abstract: A foot operated air pump rapidly inflates a pneumatic cuff wrapped around the leg of a patient. At the moment of inflation a pressure switch senses the increase in air pressure and sends a timing signal to an ultrasonic imaging system.Type: ApplicationFiled: September 30, 2013Publication date: April 2, 2015Inventors: Lindsay S. Machan, Daniel Gelbart
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Patent number: 8834449Abstract: A movable mixing disc is inserted into a regular syringe. The mixing disc has a small hole covered by a fine screen, allowing only saline solution to get behind the disc. When the plunger of the syringe is pressed, the saline solution emerges from the mixing disc hole as a high velocity jet, stirring up the settled particles. As the ejection continues, the mixing disc is pushed forward by the plunger in order to eliminate any unused volume.Type: GrantFiled: February 28, 2012Date of Patent: September 16, 2014Assignee: Ikomed Technologies, Inc.Inventors: Lindsay S. Machan, Daniel Gelbart
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Publication number: 20140254303Abstract: A movable mixing disc may be utilized in connection with a syringe. The mixing disc may comprise a hole which may be covered by a fine screen or coupled to a porous member, allowing only certain elements of a solution to pass through the mixing disc. Actuation of a plunger of the syringe may cause liquid to emerge from the mixing disc hole as a high velocity jet or other turbulent flow, stirring up any settled particles on a distal side of the mixing disc. As the ejection continues, the mixing disc may be pushed forward by the plunger in order to eliminate any unused volume. Also, the mixing disc may be moved forward by virtue of a pressure difference created by a pressure drop across the mixing disc, such as a pressure drop created as the plunger is displaced to induce fluid flow across the mixing disc.Type: ApplicationFiled: May 21, 2014Publication date: September 11, 2014Applicants: Merit Medical Systems, Inc., IKOMED Technologies, Inc.Inventors: Gregory R. McArthur, Lindsay S. Machan, Daniel Gelbart
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Patent number: 8693628Abstract: To reduce X-ray exposure while improving image quality, an area of interest is selected in the image. The image of the selected area is updated frequently, comparable to a rate of updates used today for the whole image. The rest of the image is updated at a significantly lower rate. Since the area of interest normally is a small part of the overall area, the total exposure is reduced significantly. A fast X-ray shutter, placed near the X-ray source, blocks the radiation from areas outside the area of interest. The shutter automatically retracts when the complete image is updated. The area of interest can be selected by the user or automatically selected based on activity in the image. Since most of the exposures are taken at a reduced collimation angle, limited by the area of interest, the area of interest is imaged at reduced scatter and better quality.Type: GrantFiled: December 7, 2010Date of Patent: April 8, 2014Inventors: Lindsay S. Machan, Daniel Gelbart
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Publication number: 20130226148Abstract: A movable mixing disc is inserted into a regular syringe. The mixing disc has a small hole covered by a fine screen, allowing only saline solution to get behind the disc. When the plunger of the syringe is pressed, the saline solution emerges from the mixing disc hole as a high velocity jet, stirring up the settled particles. As the ejection continues, the mixing disc is pushed forward by the plunger in order to eliminate any unused volume.Type: ApplicationFiled: February 28, 2012Publication date: August 29, 2013Inventors: Lindsay S. Machan, Daniel Gelbart
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Publication number: 20130102657Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.Type: ApplicationFiled: July 13, 2012Publication date: April 25, 2013Applicant: ANGIOTECH PHARMACEUTICALS, INC.Inventors: WILLIAM L. HUNTER, LINDSAY S. MACHAN, A. LARRY ARSENAULT
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Patent number: 8221794Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.Type: GrantFiled: March 3, 2010Date of Patent: July 17, 2012Assignee: Angiotech Pharmaceuticals, Inc.Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault, Helen M. Burt, John J. Jackson, Stephen K. Dordunoo
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Publication number: 20110202052Abstract: The disclosed system improves urine flow by increasing the inside diameter of the urethra going through the prostate by eroding the urethral wall, rather than by reducing the prostate volume. This is done by a specially designed IRE electrode, which limits the penetration depth of the electric field to the urethral wall.Type: ApplicationFiled: February 12, 2010Publication date: August 18, 2011Inventors: Daniel Gelbart, Lindsay S. Machan
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Patent number: 7983391Abstract: To reduce X-ray exposure, an area of interest is selected in the image. The image of the selected area is updated frequently, comparable to rate of updates used today for the whole image. The rest of the image is updated at a significantly lower rate. Since the area of interest normally is a small part of the overall area, the total exposure is reduced significantly. A movable X-ray shield placed near the X-ray source blocks the radiation from areas outside the area of interest. The shield automatically retracts when the complete image is updated. The area of interest can be selected by the user or automatically selected based on activity in the image.Type: GrantFiled: April 27, 2009Date of Patent: July 19, 2011Inventors: Lindsay S. Machan, Daniel Gelbart
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Publication number: 20110118825Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.Type: ApplicationFiled: June 22, 2010Publication date: May 19, 2011Applicant: ANGIOTECH PHARMACEUTICALS, INC.Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault
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Publication number: 20110075805Abstract: To reduce X-ray exposure while improving image quality, an area of interest is selected in the image. The image of the selected area is updated frequently, comparable to rate of updates used today for the whole image. The rest of the image is updated at a significantly lower rate. Since the area of interest normally is a small part of the overall area, the total exposure is reduced significantly. A fast X-ray shutter, placed near the X-ray source, blocks the radiation from areas outside the area of interest. The shutter automatically retracts when the complete image is updated. The area of interest can be selected by the user or automatically selected based on activity in the image. Since most of the exposures are taken at a reduced collimation angle, limited by the area of interest, the area of interest is imaged at reduced scatter and better quality.Type: ApplicationFiled: December 7, 2010Publication date: March 31, 2011Inventors: Lindsay S. Machan, Daniel Gelbart
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Publication number: 20110071612Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and taxol. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.Type: ApplicationFiled: June 17, 2010Publication date: March 24, 2011Applicant: ANGIOTECH PHARMACEUTICALS, INC.Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault
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Publication number: 20110066251Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and taxol. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.Type: ApplicationFiled: June 22, 2010Publication date: March 17, 2011Applicant: ANGIOTECH PHARMACEUTICALS, INC.Inventors: William L. HUNTER, Lindsay S. Machan, A. Larry Arsenault
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Publication number: 20110034823Abstract: A stent balloon is provided with two conductive rings, created by a thin metallized coating deposited directly on the balloon, adjacent to the ends of the stent. The impedance between those rings and the body of the patient is measured at different AC frequencies. As the balloon approaches the vessel wall the impedance increases rapidly. Once the balloon forms full contact with vessel wall the impedance increases slowly. The changing impedance provides a guide for optimal apposition of the stent. The same conductive rings can also detect stent slippage and stent position relative to the balloon. With the addition of an extra conductive pad and wire, stent spring-back can be measured and corrected for.Type: ApplicationFiled: September 13, 2010Publication date: February 10, 2011Inventors: Daniel Gelbart, Lindsay S. Machan
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Publication number: 20100292314Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.Type: ApplicationFiled: June 22, 2010Publication date: November 18, 2010Applicant: ANGIOTECH PHARMACEUTICALS, INC.Inventors: William L. HUNTER, Lindsay S. Machan, A. Larry Arsenault, Helen M. Burt, John K. Jackson, Stephen K. Dordunoo
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Publication number: 20100272238Abstract: To reduce X-ray exposure, an area of interest is selected in the image. The image of the selected area is updated frequently, comparable to rate of updates used today for the whole image. The rest of the image is updated at a significantly lower rate. Since the area of interest normally is a small part of the overall area, the total exposure is reduced significantly. A movable X-ray shield placed near the X-ray source blocks the radiation from areas outside the area of interest. The shield automatically retracts when the complete image is updated. The area of interest can be selected by the user or automatically selected based on activity in the image.Type: ApplicationFiled: April 27, 2009Publication date: October 28, 2010Inventors: Lindsay S. Machan, Daniel Gelbart
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Patent number: 7820193Abstract: The present invention is directed to a stent comprising (a) a balloon expandable coronary stent; and (b) paclitaxel, in an amount that when tested in a chick chorioallantoic membrane assay is anti-angiogenic.Type: GrantFiled: October 7, 2004Date of Patent: October 26, 2010Assignee: Angiotech Pharmaceuticals, Inc.Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault
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Publication number: 20100240742Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.Type: ApplicationFiled: March 3, 2010Publication date: September 23, 2010Applicant: ANGIOTECH PHARMACEUTICALS, INC.Inventors: WILLIAM L. HUNTER, LINDSAY S. MACHAN, A. LARRY ARSENAULT, HELEN M. BURT, JOHN K. JACKSON, STEPHEN K. DORDUNOO
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Publication number: 20100174356Abstract: Stent grafts are provided comprising an endoluminal stent and a graft, wherein the stent graft releases an agent which induces the in vivo adhesion of the stent graft to vessel walls, or, otherwise induces or accelerates an in vivo fibrotic reaction causing said stent graft to adhere to vessel wall. Also provided are methods for making and using such stent grafts.Type: ApplicationFiled: December 30, 2009Publication date: July 8, 2010Applicants: The University of British ColumbiaInventors: Lindsay S. MACHAN, John K. Jackson, William L. Hunter