Patents by Inventor Lindsey Jean Stretz

Lindsey Jean Stretz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotides, Compositions, and Methods for Genome Editing
    Publication number: 20240301377
    Abstract: Compositions and methods for gene editing are provided. In some embodiments, provided is a polynucleotide encoding an RNA-guided DNA binding agent such as N. meningitidis Cas9 that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits.
    Type: Application
    Filed: May 1, 2024
    Publication date: September 12, 2024
    Applicant: Intellia Therapeutics, Inc.
    Inventors: Sabin Mulepati, Lindsey Jean Stretz
  • Modified Guide RNAs for Gene Editing
    Publication number: 20240299583
    Abstract: This disclosure relates to modified guide RNAs having improved in vitro and in vivo activity in gene editing methods. This disclosure also relates to N. meningitidis Cas9 (NmeCas9) gene editing systems with modified guide RNAs.
    Type: Application
    Filed: May 1, 2024
    Publication date: September 12, 2024
    Applicant: Intellia Therapeutics, Inc.
    Inventors: Sabin Mulepati, Lindsey Jean Stretz, Michelle Young, Sung Hee Choi, Rubina Giare Parmar, Weijun Chen, Eun Soo Yoon
  • Modified Guide RNAs Comprising an Internal Linker for Gene Editing
    Publication number: 20240150761
    Abstract: This disclosure relates to modified guide RNAs comprising an internal linker for in vitro and in vivo gene editing methods.
    Type: Application
    Filed: December 7, 2023
    Publication date: May 9, 2024
    Applicant: Intellia Therapeutics, Inc.
    Inventors: Sabin Mulepati, Rubina Giare Parmar, Lindsey Jean Stretz, Michelle Young, Jasmine Josephine Bonanno, Seth C. Alexander