Abstract: Embodiments of this application provide a terminal device, including a middle frame, a heat source device, a first heat dissipation assembly, and a second heat dissipation assembly, where the first heat dissipation assembly is disposed on one side of the middle frame, the heat source device and the second heat dissipation assembly are disposed on the other side of the middle frame, and at least one of the first heat dissipation assembly and the second heat dissipation assembly is a graphene heat dissipation assembly.

Abstract: A display includes display region and a non-display region surrounding the display region. The display further includes a main circuit board, wherein an electroluminescent film layer is coated in the non-display region, and the electroluminescent film layer is electrically connected with the main circuit board. A periphery of the display region is illuminated by the electroluminescent film layer disposed at the non-display region of the display.

Abstract: The invention relates to a T cell expressing an antibody or comprising the coding sequence of the antibody or an expression vector thereof; the antibody contains an optional signal peptide, an antigen binding sequence and a mutant type Fc segment, wherein the mutant type Fc segment is a Fc segment in which amino acid residues at the 17th site and the 79th site of the IgG4 Fc segment shown by SEQ ID NO: 25 are mutated into E and Q respectively. Preferably, the T cell is a CAR-T cell. The present invention further relates to a treatment application of the T cell in malignant tumors.

Abstract: Provided are a dual-activating costimulatory molecule receptor and the use thereof. The dual-activating costimulatory molecule receptor comprises the following elements from the N-terminus to the C-terminus: a selectable signal peptide, a costimulatory signal molecule-activating single-chain antibody, an extracellular hinge area, a transmembrane region and an intracellular costimulatory signal molecule. The dual-activating costimulatory molecule receptor can produce a strong clustering effect when co-modifying T-cells with first-generation CAR-T comprising a first signal, can kill tumor cells, and at the same time, does not trigger a strong T-cell immunity or cause potentially serious toxic side effects.

Abstract: Provided is a chimeric promoter with a high transcriptional activity in T-cells. The chimeric promoter consists of an enhancer sDTS and a promoter operably linked to the enhancer. The sequence of the enhancer is as shown in SEQ ID NO: 1. The enhancer is located at the 5? or 3? terminus of the promoter. Also provided are nucleic acid constructs, vectors and T-cells comprising the chimeric promoter. The chimeric promoter can drive the efficient expression of exogenous genes in T-cells.

Abstract: Provided is a transgenic killer cell, the genome of which is stably integrated with a coding sequence comprising an antibody of a human Fc section, or an expression cassette of a coding sequence comprising a chimeric antigen receptor or an inhibitory or agonistic antibody, and an inverted terminal repeat sequence from a transposon at both ends. Also provided is a pharmaceutical composition comprising the transgenic killer cell, and uses thereof.

Abstract: An external speaker assembly and an audio apparatus are disclosed. The external speaker assembly comprises a housing, a speaker unit and a driving circuit; the external speaker assembly is detachably connected to an audio device; when the external speaker assembly is connected to the audio device, a sealed cavity is formed by the housing and a rear cover of the audio device; the speaker unit and the driving circuit are received in the sealed cavity; the driving circuit is configured to connect to the audio device, and receive an audio signal from the audio device to drive the speaker unit to produce sounds.

Abstract: A display includes display region and a non-display region surrounding the display region. The display further includes a main circuit board, wherein an electroluminescent film layer is coated in the non-display region, and the electroluminescent film layer is electrically connected with the main circuit board. A periphery of the display region is illuminated by the electroluminescent film layer disposed at the non-display region of the display.

Abstract: An external speaker assembly and an audio apparatus are disclosed. The external speaker assembly comprises a housing, a speaker unit and a driving circuit; the external speaker assembly is detachably connected to an audio device; when the external speaker assembly is connected to the audio device, a sealed cavity is formed by the housing and a rear cover of the audio device; the speaker unit and the driving circuit are received in the sealed cavity; the driving circuit is configured to connect to the audio device, and receive an audio signal from the audio device to drive the speaker unit to produce sounds.

Abstract: A mobile terminal that sends out sound via a multifunctional battery cover and a method thereof. The mobile terminal includes a processing module that identifies a battery cover including a piezoelectric ceramic speaker based on an ID signal output by the battery cover and outputs an audio signal to the piezoelectric ceramic speaker.

Abstract: A method for providing a multi-function back cover to a mobile terminal and a mobile terminal thereof includes: providing a plurality of test points on a PCB of a main body of the mobile terminal in advance; providing a plurality of pogo pins at positions corresponding to the test points on a back cover of the mobile terminal, and installing the back cover of the mobile terminal on the main body of the mobile terminal, such that the pogo pins connect with the test points to provide a corresponding function of the back cover of the mobile terminal.

Abstract: A mobile terminal that sends out sound via a multifunctional battery cover and a method thereof. The mobile terminal includes a processing module that identifies a battery cover including a piezoelectric ceramic speaker based on an ID signal output by the battery cover and outputs an audio signal to the piezoelectric ceramic speaker.

Abstract: A method for providing a multi-function back cover to a mobile terminal and a mobile terminal thereof includes: providing a plurality of test points on a PCB of a main body of the mobile terminal in advance; providing a plurality of pogo pins at positions corresponding to the test points on a back cover of the mobile terminal, and installing the back cover of the mobile terminal on the main body of the mobile terminal, such that the pogo pins connect with the test points to provide a corresponding function of the back cover of the mobile terminal.

Abstract: The invention belongs to the field of molecular biology, and relates to an efficient and safe transposon integration system and use thereof. The invention also relates to a nucleic acid construct and use thereof. Preferably, the nucleic acid construct comprises the following elements in order: a 5?-terminal repeat sequence of a transposon, a multiple cloning site, a polyA tailing signal sequence, a 3?-terminal repeat sequence of a transposon, a sequence encoding a transposase and a promoter controlling expression of the transposase; wherein the multiple cloning site is used for operably inserting an exogenous gene and optionally a promoter controlling expression of the exogenous gene; the polyA tailing signal sequence has a polyA tailing signal function in both forward and reverse directions; and the direction of the expression cassette of the transposase is opposite to the direction of the exogenous gene expression cassette.