Abstract: Provided are a preparation method for a CTL cell and an application thereof. The preparation method comprises the following steps of: inducing a CTL cell by using a tumor antigen PAP-GM-CSF sensitized DC cell; and knocking out a PD-1 gene of the CTL cell to obtain a PD-1 knock-out CTL cell. The CTL cell obtained by the preparation method can be used for preparing drugs for treatment of prostate cancer, especially for treating PAP-positive prostate cancer. The CTL cell does not cause CTL cell failure and anergy due to the tumor-expressed PD-L1 after being transfused into the body, thereby producing efficient specific cytotoxic effect on a tumor cell and improving the curative effect and reducing the side effect.

Abstract: A radiation therapy system is disclosed. The radiation therapy system includes a gantry, a first radiation source, and a second radiation source. The gantry is configured to have a cavity extending in a direction along a rotation axis, and the cavity is configured to house a target object. The first radiation source is mounted on the gantry, and configured to emit a treatment beam to a treatment area of the target object. The second radiation source is mounted on the gantry, and configured to emit an imaging beam to an imaging area of the target object. The treatment area partially overlaps the imaging area. A rotation plane of the first radiation source and a rotation plane of the second radiation source are distributed in a direction along the rotation axis.

Abstract: A system is provided for mitigating a road network congestion. The system includes a plurality of motor vehicles positioned in associated locations in a road network. Each vehicle has one or more sensors generating an input and a Telematics Control Unit (TCU) for generating at least one location signal for a location of the associated motor vehicle and at least one event signal for an event related to the associated motor vehicle, with the location signal and the event signal corresponding to a High Speed Vehicle Telemetry Data (HSVT data) based on the input from the sensors. The system further includes a computer, which communicates with a display device and the TCUs. The computer includes a processor and a computer readable medium including instructions, such that the processor is programmed to identify the congestion and determine that the congestion is a recurring or a non-recurring congestion.

Abstract: A system is provided for mitigating a road network congestion. The system includes a plurality of motor vehicles positioned in associated locations in a road network. Each vehicle has one or more sensors generating an input and a Telematics Control Unit (TCU) for generating at least one location signal for a location of the associated motor vehicle and at least one event signal for an event related to the associated motor vehicle, with the location signal and the event signal corresponding to a High Speed Vehicle Telemetry Data (HSVT data) based on the input from the sensors. The system further includes a computer, which communicates with a display device and the TCUs. The computer includes a processor and a computer readable medium including instructions, such that the processor is programmed to identify the congestion and determine that the congestion is a recurring or a non-recurring congestion.

Abstract: A computer is provided for a system for detecting, characterizing, and mitigating road network congestion. The system includes a plurality of motor vehicles. Each motor vehicle includes a telematics control unit (TCU) for generating one or more location signals for a location of the associated motor vehicle and one or more event signals for an event related to the associated motor vehicle. The computer includes one or more processors for receiving the location signal and/or the event signal from the TCU of the associated motor vehicles. The computer further includes a non-transitory computer readable storage medium (CRM) including instructions, such that the processor is programmed to identify a location of the road network congestion at a current time step. The processor is further programmed to track the road network congestion and predict the road network congestion at a next time step.

Abstract: The present disclosure provides a method of data protection for a three-dimensional NAND memory. The method includes programming a memory cell of the 3D NAND memory according to programming data; and backing up a portion of the programming data associated with the memory cell in response to a program loop count (PLC) that is larger than a threshold value, where the PLC tracks a repeated number of the programming of the memory cell. A previous PLC can be set as the threshold value, where the previous PLC was used by a previous programming operation and was collected after the memory cell was programmed successfully to a previous target logic state.

Abstract: A vehicle communication and control system includes a servicing host capable of exchanging data with a vehicle. The servicing host provides a vehicle service and includes a service identifier (ID) that indicates the vehicle service. The vehicle is configured to actively detect the service ID and to determine the vehicle service in response to detecting the service ID. The vehicle and the servicing host establish a wireless connection to exchange data and automatically initiate the vehicle service in response to detecting the service ID.

Abstract: Implementations of the present disclosure provide a memory apparatus that includes a plurality of memory cells stored with memory data in N dies. Each of the N dies includes M planes. Each of the M planes includes a memory block. The apparatus also includes a controller configured to determine J layers in the memory block in each of the M planes and in each of the N dies, each of the J layers comprising a pair of adjacent gate conductive layers. The controller is also configured to determine M sets of stripes. Each of the M sets of stripes comprising a plurality of data portions stored in a respective one of the M planes. The controller is further configured to determine M sets of parity data portions. The controller is further configured to control a temporary storage unit to store the M sets of parity data portions.

Abstract: Implementations of the present disclosure provide a memory apparatus that includes a plurality of memory cells stored with memory data in N dies. Each of the N dies includes M planes. Each of the M planes includes a memory block. The apparatus also includes a controller configured to determine J layers in the memory block in each of the M planes and in each of the N dies, each of the J layers comprising a pair of adjacent gate conductive layers. The controller is also configured to determine M sets of stripes. Each of the M sets of stripes comprising a plurality of data portions stored in a respective one of the M planes. The controller is further configured to determine M sets of parity data portions. The controller is further configured to control a temporary storage unit to store the M sets of parity data portions.

Abstract: A vehicle communication and control system includes a servicing host capable of exchanging data with a vehicle. The servicing host provides a vehicle service and includes a service identifier (ID) that indicates the vehicle service. The vehicle is configured to actively detect the service ID and to determine the vehicle service in response to detecting the service ID. The vehicle and the servicing host establish a wireless connection to exchange data and automatically initiate the vehicle service in response to detecting the service ID.

Abstract: The invention relates to rubber comprised of a reaction product of at least one diene-based elastomer, branched polyethylenimine oligomer and filler reinforcement comprised of at least one of rubber reinforcing carbon black and precipitated silica. The invention further relates to a tire with a component comprised of such rubber composition.

Abstract: The invention relates to rubber comprised of a reaction product of at least one diene-based elastomer, branched polyethylenimine oligomer and filler reinforcement comprised of at least one of rubber reinforcing carbon black and precipitated silica. The invention further relates to a tire with a component comprised of such rubber composition.

Abstract: There is disclosed a vulcanizable rubber composition comprising: (A) a diene based elastomer, (B) from 50 to 150 parts by weight, per 100 parts by weight of elastomer (phr), of silica; (C) from 0.15 to 0.45 phr of a polymeric amine comprising a primary amine functionality; and (D) from 1.5 to 2.5 parts by weight, per 1 part by weight of the polymeric amine, of an aromatic carboxylic acid or aromatic acid anhydride.

Abstract: This invention relates to a tire having a rubber component, such as a tread. with filler reinforcement containing surface modified graphene and precipitated silica which may be or may include pre-hydrophobated precipitated silica.

Abstract: An online shopping basket is acquired by a buyer from an online store and is customized according to rules specified by the buyer. The buyer places zero or more items in the online shopping basket(s) before they are given to at least one shopper by the online store. The shopper(s) may further customize the online shopping basket(s) with rules that do not conflict with those specified by the buyer. The shopper(s) then place zero or more items in the online shopping basket(s) and return the basket(s) to the online store. Multiple online shopping baskets are merged into a single basket, and the buyer reviews the items in the merged online shopping basket and adds or removes items as necessary. The buyer then purchases the remaining items from the online store.

Abstract: This invention relates to a rubber composition comprised of at least one conjugated diene-based elastomer containing triglyceride based algae oil and to a tire with a component thereof.

Abstract: There is disclosed a vulcanizable rubber composition comprising: (A) a diene based elastomer, (B) from 50 to 150 parts by weight, per 100 parts by weight of elastomer (phr), of silica; (C) from 0.15 to 0.45 phr of a polymeric amine comprising a primary amine functionality; and (D) from 1.5 to 2.5 parts by weight, per 1 part by weight of the polymeric amine, of an aromatic carboxylic acid or aromatic acid anhydride.

Abstract: The invention relates to functionalization of diene-based elastomers with end-chain or in-chain functional groups to promote good dispersion of graphene and carbon nanotubes, and enhance strong interaction between elastomers and graphene and carbon nanotubes. This invention also relates to preparation of rubber reinforced with at least one of graphene and carbon nanotubes with functionalized diene-based elastomer and tire with component thereof.

Abstract: This invention relates to a tire having a rubber tread containing functionalized carbon nanotubes and particulate reinforcement comprised of precipitated silica.