Patents by Inventor Ling Hon Matthew Chu

Ling Hon Matthew Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-12 Variants and Uses Thereof
    Publication number: 20240010696
    Abstract: IL-12 variants are provided. Also provided are antibodies that specifically bind to PD1. Also provided are fusion proteins of IL-12 variants and anti-PD1 antibodies. Also provided are uses of these IL-12 variants, anti-PD1 antibodies, fusion proteins, and related compositions and methods.
    Type: Application
    Filed: June 15, 2023
    Publication date: January 11, 2024
    Applicant: Pfizer Inc.
    Inventors: James Reasoner APGAR, Javier Fernando CHAPARRO RIGGERS, Ling Hon Matthew CHU, Tzu-Hsuan HUANG, Kritika MOHAN, Lidia MOSYAK, Edward Derrick PASCUA, James Travis PATTERSON, Gabriel Roy STARBECK-MILLER, Dirk Michael ZAJONC
  • BISPECIFIC IMMUNE CELL ENGAGERS WITH BINDING SPECIFICITY FOR HLA-G AND ANOTHER ANTIGEN
    Publication number: 20230235064
    Abstract: Provided herein are bispecific immune cell engagers with binding specificity for HLA-G and an additional antigen, including pharmaceutical compositions, diagnostic compositions, and kits.
    Type: Application
    Filed: June 10, 2021
    Publication date: July 27, 2023
    Inventors: Courtney Beers, Ling-Hon Matthew Chu, Doug Hodges, Christina M. Kochel
  • IL-15 Variants and Uses Thereof
    Publication number: 20210324028
    Abstract: The present invention relates to human interleukin 15 (IL-15) variants that have therapeutic and diagnostic use, and methods for making thereof. The present invention also provides fusion proteins comprising a human IL-15 variant. Also provided are methods of stimulating or suppressing immune responses in a mammal, and methods of treating a disorder (e.g., cancer) using the IL-15 variants or the fusion protein of such IL-15 variants.
    Type: Application
    Filed: June 24, 2021
    Publication date: October 21, 2021
    Applicant: Pfizer Inc.
    Inventors: Yik Andy Yeung, Reid Martin Renny Feldman, Ling Hon Matthew Chu, Javier Fernando Chaparro Riggers, Ivana Djuretic, Laura Lin, Lidia Mosyak
  • IL-15 variants and uses thereof
    Patent number: 11059876
    Abstract: The present invention relates to human interleukin 15 (IL-15) variants that have therapeutic and diagnostic use, and methods for making thereof. The present invention also provides fusion proteins comprising a human IL-15 variant. Also provided are methods of stimulating or suppressing immune responses in a mammal, and methods of treating a disorder (e.g., cancer) using the IL-15 variants or the fusion protein of such IL-15 variants.
    Type: Grant
    Filed: February 26, 2019
    Date of Patent: July 13, 2021
    Assignee: PFIZER INC.
    Inventors: Yik Andy Yeung, Reid Martin Renny Feldman, Ling Hon Matthew Chu, Javier Fernando Chaparro Riggers, Ivana Djuretic, Laura Lin, Lidia Mosyak
  • IL-15 Variants and Uses Thereof
    Publication number: 20190263877
    Abstract: The present invention relates to human interleukin 15 (IL-15) variants that have therapeutic and diagnostic use, and methods for making thereof. The present invention also provides fusion proteins comprising a human IL-15 variant. Also provided are methods of stimulating or suppressing immune responses in a mammal, and methods of treating a disorder (e.g., cancer) using the IL-15 variants or the fusion protein of such IL-15 variants.
    Type: Application
    Filed: February 26, 2019
    Publication date: August 29, 2019
    Applicant: Pfizer Inc.
    Inventors: Yik Andy Yeung, Reid Martin Renny Feldman, Ling Hon Matthew Chu, Javier Fernando Chaparro Riggers, Ivana Djuretic, Laura Lin, Lidia Mosyak