Patents by Inventor Ling Hua

Ling Hua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190048376
    Abstract: A method is disclosed for hydrolyzing an alpha-1,3 or alpha-1,6 glucosyl-glucose linkage in a saccharide (disaccharide or oligosaccharide). This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,3 or alpha-1,6 glucosyl-glucose linkage of the saccharide. This method is useful for reducing the amount of oligosaccharides in a filtrate isolated from a glucan synthesis reaction, for example.
    Type: Application
    Filed: May 24, 2018
    Publication date: February 14, 2019
    Inventors: KEVIN D. NAGY, ERWIN F. COLUMBUS-HAGO, JAYARAMA K. SHETTY, SUSAN MARIE HENNESSEY, ROBERT DICOSIMO, LING HUA, RODRIGO RAMIREZ, ZHONGMEI TANG, ZHEYONG YU
  • Patent number: 10185098
    Abstract: An optical fiber connector device includes an optical fiber connector and an insert unit. The insert unit hash a housing and a connecting mechanism. The housing surrounds an axis, and has an outer wall, a surrounding wall, and a cover member. The outer wall defines a first insert opening on the axis, and has a main opening spaced apart from the axis. The outer wall and the surrounding wall are molded as one piece. The cover member covers removably the main opening. The connecting mechanism has a first connecting member surrounded by the outer wall and connected to the optical fiber connector, and a second connecting member surrounded by the surrounding wall, coupled to the first connecting member, and adapted to be connected to another optical fiber connector.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: January 22, 2019
    Assignees: AMPHENOL FIBER OPTIC TECHNOLOGY (SHENZHEN) CO., LTD., GLORIOLE ELECTROPTIC TECHNOLOGY CORP.
    Inventors: Bo-Lin Jiang, Song-Sheng Li, Min Chen, Ling-Hua Zhu
  • Publication number: 20180273999
    Abstract: A method is disclosed for hydrolyzing an alpha-1,5 glucosyl-fructose linkage in a saccharide (disaccharide or oligosaccharide) such as leucrose. This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase or glucoamylase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,5 glucosyl-fructose linkage of the saccharide. This method is useful for reducing the amount of leucrose in a filtrate isolated from a glucan synthesis reaction, for example.
    Type: Application
    Filed: May 10, 2018
    Publication date: September 27, 2018
    Inventors: KEVIN D NAGY, ERWIN F. COLUMBUS-HAGO, JAYARAMA K. SHETTY, SUSAN MARIE HENNESSEY, ROBERT DICOSIMO, LING HUA, RODRIGO RAMIREZ, ZHONGMEI TANG, ZHEYONG YU
  • Patent number: 9988657
    Abstract: A method is disclosed for hydrolyzing an alpha-1,3 or alpha-1,6 glucosyl-glucose linkage in a saccharide (disaccharide or oligosaccharide). This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,3 or alpha-1,6 glucosyl-glucose linkage of the saccharide. This method is useful for reducing the amount of oligosaccharides in a filtrate isolated from a glucan synthesis reaction, for example.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: June 5, 2018
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Kevin D Nagy, Erwin Columbus Hago, Jayarama K Shetty, Susan Marie Hennessey, Robert Dicosimo, Ling Hua, Rodrigo Ramirez, Zhongmei Tang, Zheyong Yu
  • Publication number: 20180148704
    Abstract: The present compositions and methods relate to a beta-mannanase from Bacillus hemicellulosilyticus, polynucleotides encoding the beta-mannanase, and methods of make and/or use thereof. Formulations containing the beta-mannanase are suitable for use in hydrolyzing lignocellulosic biomass substrates, especially those comprising a measurable level of galactoglucomannan (GGM) and/or glucomannan (GM).
    Type: Application
    Filed: January 16, 2018
    Publication date: May 31, 2018
    Inventors: STEVEN LE, LING HUA, ROSALYN LAU, ZHEN QIAN, ZHEYONG YU
  • Patent number: 9982284
    Abstract: A method is disclosed for hydrolyzing an alpha-1,5 glucosyl-fructose linkage in a saccharide (disaccharide or oligosaccharide) such as leucrose. This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase or glucoamylase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,5 glucosyl-fructose linkage of the saccharide. This method is useful for reducing the amount of leucrose in a filtrate isolated from a glucan synthesis reaction, for example.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: May 29, 2018
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Kevin D Nagy, Erwin Columbus Hago, Jayarama K Shetty, Susan Marie Hennessey, Robert Dicosimo, Ling Hua, Rodrigo Ramirez, Zhongmei Tang, Zheyong Yu
  • Patent number: 9964712
    Abstract: An optical fiber connector is for linking a standard connector head member and a lucent connector tail member, and includes a first connecting member and a second connecting member. The first connecting member is adapted to be detachably connected to the standard connector head member, and has a first hollow body that defines a first passage. The second connecting member is adapted to be detachably coupled to the lucent connector tail member, is connected to the first connecting member, and has a second hollow body that defines a second passage. The second passage is in spatial communication with the first passage and has a diameter that is 1.3 millimeters. The first connecting member and the second connecting member are molded as one piece.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: May 8, 2018
    Assignee: AMPHENOL FIBER OPTIC TECHNOLOGY (SHENZHEN) CO., LTD.
    Inventors: Bo-Lin Jiang, Song-Sheng Li, Min Chen, Ling-Hua Zhu
  • Publication number: 20180112203
    Abstract: The present teachings provide an amylase with maltogenic properties. Nucleic acids encoding the maltogenic amylase and variants thereof, expression vectors, formulations, and host cells are also provided. Additional embodiments of the present teachings provide various methods of use and methods of manufacturing.
    Type: Application
    Filed: November 15, 2013
    Publication date: April 26, 2018
    Applicant: DANISCO US INC.
    Inventors: RICHARD R. BOTT, LING HUA, ZHEN QIAN, CHRISTOPHER L. RIFE, JAYARAMA K. SHETTY, ZHONGMEI TANG, ZHEYONG YU, BO ZHANG
  • Publication number: 20180055844
    Abstract: Provided herein are methods of treating, preventing and/or managing cancers, which comprise administering to a patient 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof, or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or polymorph thereof.
    Type: Application
    Filed: April 11, 2017
    Publication date: March 1, 2018
    Inventors: George W. Muller, Peter H. Schafer, Hon-Wah Man, Ling-Hua Zhang, Anita Gandhi, Rajesh Chopra
  • Patent number: 9890374
    Abstract: The present compositions and methods relate to a thermostable carbonic anhydrases, polynucleotides encoding the carbonic anhydrase, and methods of make and/or use thereof. Formulations containing the carbonic anhydrase are suitable for use in extracting carbon dioxide.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: February 13, 2018
    Assignee: DANISCO US INC
    Inventors: Jing Ge, Ling Hua, Ayrookaran J. Poulose
  • Patent number: 9879245
    Abstract: The present compositions and methods relate to a beta-mannanase from Bacillus hemicellulosilyticus, polynucleotides encoding the beta-mannanase, and methods of make and/or use thereof. Formulations containing the beta-mannanase are suitable for use in hydrolyzing lignocellulosic biomass substrates, especially those comprising a measurable level of galactoglucomannan (GGM) and/or glucomannan (GM).
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: January 30, 2018
    Assignee: DANISCO US INC.
    Inventors: Ling Hua, Rosalyn Lau, Steven Le, Zhen Qian, Zheyong Yu
  • Patent number: 9835807
    Abstract: An optical fiber connector for connecting to an optical fiber cable includes a shell, a hollow guiding device, and a socket device. The hollow guiding device is connected to the shell. The socket device includes a hollow socket unit and a ferrule. The socket unit is formed as one piece and is detachably connected to an end of the guiding device opposite to the shell such that the optical fiber cable extends through the guiding device and the shell into the socket unit. The ferrule is disposed in the socket unit and is for connecting to one end of the optical fiber cable.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: December 5, 2017
    Assignees: AMPHENOL FIBER OPTIC TECHNOLOGY (SHENZHEN) CO., LTD., GLORIOLE ELECTROPTIC TECHNOLOGY CORP.
    Inventors: Ling-Hua Zhu, Song-Sheng Li, Xue-Wu Lei, Bo-Lin Jiang
  • Publication number: 20170314050
    Abstract: A method is disclosed for hydrolyzing an alpha-1,3 or alpha-1,6 glucosyl-glucose linkage in a saccharide (disaccharide or oligosaccharide). This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,3 or alpha-1,6 glucosyl-glucose linkage of the saccharide. This method is useful for reducing the amount of oligosaccharides in a filtrate isolated from a glucan synthesis reaction, for example.
    Type: Application
    Filed: February 26, 2015
    Publication date: November 2, 2017
    Inventors: KEVIN D NAGY, Erwin Columbus Hago, Jayarama K Shetty, Susan Marie Hennessey, Robert Dicosimo, Ling Hua, Rodrigo Ramirez, Zhongmei Tang, Zheyong Yu
  • Patent number: 9772453
    Abstract: An optical fiber plug adapted to be connected to an optical fiber socket and a first optical fiber cable includes a plug sleeve unit, a plug unit, a plug guiding unit, and a coupling unit. The coupling unit includes a coupling seat, a coupling ring, and a coupling cover movable between a locked position and a released position. When the coupling cover is at the locked position, the optical fiber plug is locked to the optical fiber socket by the coupling ring. When the coupling cover is moved from the locked position to the released position, the coupling ring is urged resiliently by the coupling cover to release the optical fiber plug, thereby permitting separation of the optical fiber plug from the optical fiber socket.
    Type: Grant
    Filed: July 25, 2016
    Date of Patent: September 26, 2017
    Assignee: Amphenol Fiber Optic Technology (Shenzhen) Co., Ltd.
    Inventors: Ling-Hua Zhu, Song-Sheng Li, Xue-Wu Lei
  • Patent number: 9765374
    Abstract: A fungal alpha-amylase is provided from Aspergillus fumigatus (AfAmyl). AfAmyl has an optimal pH of 3.5 and is operable at 30-75 degrees C., allowing the enzyme to be used in combination with a glucoamylase and an isoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AfAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DPI+DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: September 19, 2017
    Assignee: DANISCO US INC
    Inventors: Ling Hua, Martijn Scheffers, Marco Van Brussel, Casper Vroemen, Bo Zhang, Zhengong Zhang
  • Publication number: 20170242196
    Abstract: An optical fiber connector device includes an optical fiber connector and an insert unit. The insert unit has a housing and a connecting mechanism. The housing surrounds an axis, and has an outer wall, a surrounding wall, and a cover member. The outer wall defines a first insert opening on the axis, and has a main opening spaced apart from the axis. The outer wall and the surrounding wall are molded as one piece. The cover member covers removably the main opening. The connecting mechanism has a first connecting member surrounded by the outer wall and connected to the optical fiber connector, and a second connecting member surrounded by the surrounding wall, coupled to the first connecting member, and adapted to be connected to another optical fiber connector.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 24, 2017
    Inventors: Bo-Lin JIANG, Song-Sheng LI, Min CHEN, Ling-Hua ZHU
  • Publication number: 20170242198
    Abstract: An optical fiber plug adapted to be connected to an optical fiber socket and a first optical fiber cable includes a plug sleeve unit, a plug unit, a plug guiding unit, and a coupling unit. The coupling unit includes a coupling seat, a coupling ring, and a coupling cover movable between a locked position and a released position. When the coupling cover is at the locked position, the optical fiber plug is locked to the optical fiber socket by the coupling ring. When the coupling cover is moved from the locked position to the released position, the coupling ring is urged resiliently by the coupling cover to release the optical fiber plug, thereby permitting separation of the optical fiber plug from the optical fiber socket.
    Type: Application
    Filed: July 25, 2016
    Publication date: August 24, 2017
    Inventors: Ling-Hua ZHU, Song-Sheng LI, Xue-Wu LEI
  • Patent number: 9678294
    Abstract: An optical fiber distribution apparatus includes a panel extending along a first direction and formed with a first mounting hole and at least two second mounting holes spaced apart from the first mounting hole along the first direction. A plurality of rows of optical fiber connector adapters are arranged in a stack in a direction transverse to the first direction and are inserted into the first mounting hole. At least two multi-fiber push on (MPO) connector adapters are respectively inserted into the at least two second mounting holes.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: June 13, 2017
    Assignees: AMPHENOL FIBER OPTIC TECHNOLOGY, GLORIOLE ELECTROPTIC TECHNOLOGY CORP., SHEN ZHEN WONDERWIN TECHNOLOGY CO., LTD.
    Inventors: Rui Yin, Song-Sheng Li, Bo-Lin Jiang, Ling-Hua Zhu, Jim Lin, Chia-Hua Wu
  • Publication number: 20170153395
    Abstract: An optical fiber connector is for linking a standard connector head member and a lucent connector tail member, and includes a first connecting member and a second connecting member. The first connecting member is adapted to be detachably connected to the standard connector head member, and has a first hollow body that defines a first passage. The second connecting member is adapted to be detachably coupled to the lucent connector tail member, is connected to the first connecting member, and has a second hollow body that defines a second passage. The second passage is in spatial communication with the first passage and has a diameter that is 1.3 millimeters. The first connecting member and the second connecting member are molded as one piece.
    Type: Application
    Filed: June 15, 2016
    Publication date: June 1, 2017
    Inventors: Bo-Lin JIANG, Song-Sheng LI, Min CHEN, Ling-Hua ZHU
  • Publication number: 20170153394
    Abstract: An optical fiber connector for connecting to an optical fiber cable includes a shell, a hollow guiding device, and a socket device. The hollow guiding device is connected to the shell. The socket device includes a hollow socket unit and a ferrule. The socket unit is formed as one piece and is detachably connected to an end of the guiding device opposite to the shell such that the optical fiber cable extends through the guiding device and the shell into the socket unit. The ferrule is disposed in the socket unit and is for connecting to one end of the optical fiber cable.
    Type: Application
    Filed: June 10, 2016
    Publication date: June 1, 2017
    Inventors: Ling-Hua ZHU, Song-Sheng LI, Xue-Wu LEI, Bo-Lin JIANG