Abstract: Provided are an antibody having effective neutralizing activity against RSV or an antigen-binding fragment thereof. The provided anti-RSV antibody or antigen-binding fragment thereof can be used as a drug for treating or preventing RSV infection or symptoms related to RSV infection. The provided RSV antibody, after humanization, can bind RSV-F protein with high affinity. In addition, experiments show that it is significantly better than palivizumab at providing protection against RSV challenge.

Abstract: The present disclosure relates to antibodies and antibody derivatives that bind to MSLN and methods of using the same. In certain embodiments, the antibody or antibody derivative disclosed herein comprises a single domain antibody that binds to MSLN.

Abstract: The invention relates to a molecular peptide mutant with a high ester bond formation efficiency, the amino acid sequence of which is as shown in SEQ ID NO: 1. The invention introduces mutations at three sites on the basis of not affecting the spatial structure of Catcher, and through three mutations, obtains the Catcher mutant EBCatcher, which significantly improves the stability of the Catcher in water solution and can improve the binding efficiency to EBTag.

Abstract: Disclosed herein are combined devices and methods of manufacturing such combined devices. The combined devices disclosed herein include an analyte sensor including a sensor probe; an infusion set hub including a cannula; and a flexible base. The analyte sensor and infusion set hub are attached to the flexible base such that movement of one of the analyte sensor and the infusion set hub is substantially not transferred to the other one of the analyte sensor and the infusion set hub.

Abstract: A smart acoustic information recognition-based welded weld impact quality determination method and system, comprising: controlling a tip of an ultrasonic impact gun (1) to perform impact treatment on a welded weld with different treatment pressures, treatment speeds, treatment angles and impact frequencies, obtaining acoustic signals during the impact treatment, calculating feature values of the acoustic signals, and constructing an acoustic signal sample set including various stress conditions; marking the acoustic signal sample set according to impact treatment quality assessment results for the welded weld; establishing a multi-weight neural network model, and using the marked acoustic signal sample set to train the multi-weight neural network model; obtaining feature values of welded weld impact treatment acoustic signals to be determined, inputting the feature values into the trained multi-weight neural network model, and outputting determination results for welded weld impact treatment quality to be det

Abstract: The invention relates to a molecular peptide mutant, the amino acid sequence of which is as shown in SEQ ID NO: 1. In the invention, SpyCatcher is designed and modified to obtain a molecular peptide SpyCatcher-21 with stimulus response to pH on the basis of not affecting the formation of isopeptide bonds, and Pro is introduced into a key loop of the SpyCatcher-21 through analysis of the crystal structure to reduce the flexibility of the loop and obtain a mutant SpyCatcher-21_A82P, which can raise ligation efficiency with SpyTag. The SpyCatcher-21_A82P can be used to achieve double-enzyme catalysis according to objective needs by changing the pH of the environment to obtain different degrees of coupling, or obtain a three-enzyme coupled catalytic system through electrostatic interaction with a positively charged enzyme.

Abstract: The present disclosure provides a method for increasing a methionine content in grains by gene knockout. A maize ZmMETS2 gene is knocked out by a CRISPR/Cas9 technology, and it is found that the methionine content in maize grains is increased to a certain extent after the gene is knocked out. In the present disclosure, the CRISPR/Cas9 target site of the maize ZmMETS2 gene is designed and a function of the gene is found to significantly affect the methionine content. This provides a reference for CRISPR researches of the gene in maize and other crops, and provides a theoretical basis for methionine metabolism of the maize and other crops. Accordingly, the deficiency of human amino acid nutrition is alleviated by increasing the methionine content of transgenic plants.

Abstract: The present invention provides a method for producing a manganese-doped nickel molybdate electrode material including mixing a nickel salt solution with a manganese salt solution to form a mixture; adding a molybdate solution into the mixture and being subject to a thermal reaction; and obtaining the manganese-doped nickel molybdate electrode material after washing and drying of the reaction product. The nickel salt includes one or more of nickel nitrate, nickel chloride, and nickel acetate; the manganese salt includes one or more of manganese chloride, manganese nitrate, and manganese sulfate; and the molybdate includes one or more of sodium molybdate or ammonium molybdate. The present method utilizes a single reaction to produce a Mn-doped NiMoO4 electrode material, which does not require using nickel molybdate as an intermediate product. The method simplifies the preparation process and makes it easy to be adjusted, thereby improving the electrochemical properties of the electrode material.

Abstract: A composite motor having high-precision positioning, comprising: a housing (1), a rough positioning assembly, a hollow output shaft (2), a fine positioning assembly, a power switching apparatus and a controller (6). A stepper motor (3) in the rough positioning assembly is responsible for rough positioning of the composite motor, an annular travelling wave ultrasonic motor in the fine positioning assembly is responsible for tail end fine positioning of the composite motor, and the controller (6) implements power output switching between the annular travelling wave ultrasonic motor and the stepper motor (3). The composite motor effectively solves the problem that annular travelling wave ultrasonic motors which operate continuously for a long time have a short service life, and ensures high-precision positioning while also extending motor service life.

Abstract: Disclosed is a quaternion multi-degree-of-freedom neuron-based multispectral welding image recognition method, comprising: using three cameras having different wavebands to obtain multispectral weld pool images, and respectively performing pre-processing and edge extraction on the weld pool images having the different wavebands obtained at a same moment by the three cameras; establishing a quaternion-based multispectral weld pool image edge model; extracting low-frequency features after a quaternion discrete cosine transform; using a quaternion-based multi-degree-of-freedom neuron network to perform classification, training and recognition on edge features of the multispectral weld pool images. Compared to traditional means, the present invention has multiple recognition information sources, strong anti-interference capabilities and high recognition accuracy.

Abstract: Disclosed is a quaternion multi-degree-of-freedom neuron-based multispectral welding image recognition method, comprising: using three cameras having different wavebands to obtain multispectral weld pool images, and respectively performing pre-processing and edge extraction on the weld pool images having the different wavebands obtained at a same moment by the three cameras; establishing a quaternion-based multispectral weld pool image edge model; extracting low-frequency features after a quaternion discrete cosine transform; using a quaternion-based multi-degree-of-freedom neuron network to perform classification, training and recognition on edge features of the multispectral weld pool images. Compared to traditional means, the present invention has multiple recognition information sources, strong anti-interference capabilities and high recognition accuracy.

Abstract: A composite motor having high-precision positioning, comprising: a housing (1), a rough positioning assembly, a hollow output shaft (2), a fine positioning assembly, a power switching apparatus and a controller (6). A stepper motor (3) in the rough positioning assembly is responsible for rough positioning of the composite motor, an annular travelling wave ultrasonic motor in the fine positioning assembly is responsible for tail end fine positioning of the composite motor, and the controller (6) implements power output switching between the annular travelling wave ultrasonic motor and the stepper motor (3). The composite motor effectively solves the problem that annular travelling wave ultrasonic motors which operate continuously for a long time have a short service life, and ensures high-precision positioning while also extending motor service life.

Abstract: A smart acoustic information recognition-based welded weld impact quality determination method and system, comprising: controlling a tip of an ultrasonic impact gun (1) to perform impact treatment on a welded weld with different treatment pressures, treatment speeds, treatment angles and impact frequencies, obtaining acoustic signals during the impact treatment, calculating feature values of the acoustic signals, and constructing an acoustic signal sample set including various stress conditions; marking the acoustic signal sample set according to impact treatment quality assessment results for the welded weld; establishing a multi-weight neural network model, and using the marked acoustic signal sample set to train the multi-weight neural network model; obtaining feature values of welded weld impact treatment acoustic signals to be determined, inputting the feature values into the trained multi-weight neural network model, and outputting determination results for welded weld impact treatment quality to be det

Abstract: An antenna structure includes a metal frame, at least one feed source, and a feed portion. The metal frame includes at least one radiating portion and at least one slot. The at least one slot is disposed in the at least one radiating portion or adjacent to the at least one radiating portion. The at least one feed source and the at least one radiating portion form a first antenna. The feed portion and the at least one slot form a second antenna. The at least one feed source supplies an electric current for the first antenna, thereby exciting a first working mode and generating a radiation signal in a first frequency band. The feed portion spans the at least one slot to supply the electric current for the second antenna, thereby exciting a second working mode and generating a radiation signal in a second frequency band.

Abstract: An antenna structure applied in a wireless communication device includes a metal frame. The wireless communication device includes at least one electronic component. The metal frame includes a substrate. The substrate includes an antenna. The antenna includes a feed portion and a gap. The feed portion spans the gap. The metal frame is spaced from the electronic component. A clearance is formed between the metal frame and the electronic component.

Abstract: A gel for protein electrophoresis includes a separating gel and a stacking gel disposed on the separating gel. The separating gel is a polyacrylamide gel including a surfactant, and is alkaline. The surfactant of the separating gel includes 0.025-0.1% (m/v) of sodium lauroyl sarcosinate. The ratio of the molar concentration of the surfactant to the mass concentration of a loading protein is between 0.04 mmol/g and 11.56 mmol/g.

Abstract: This application discloses a load balancing method and apparatus, and a device, and relates to the field of network technologies. The method includes: after a packet sent by a server is received, determining whether the packet is a first packet of a flowlet, if the packet is the first packet of the flowlet, determining a destination switch based on a destination address of the packet, determining a weight value of at least one equal-cost path associated with the destination switch in a stored equal-cost path weight table, where the equal-cost path weight table stores a correspondence between the at least one equal-cost path and the weight value, and scheduling, based on the weight value of the at least one equal-cost path, the packet onto a corresponding equal-cost path for transmission.

Abstract: The invention relates to a method for real-time scheduling of multi-energy complementary micro-grids based on a Rollout algorithm, which is technically characterized by comprising the following steps of: Step 1, setting up a moving-horizon Markov decision process model for the real-time scheduling of the multi-energy complementary micro-grids with random new-energy outputs, and establishing constraint conditions for the real-time scheduling; Step 2, establishing a target function of the real-time scheduling; Step 3, dividing a single complete scheduling cycle into a plurality of scheduling intervals, and finding one basic feasible solution meeting the constraint conditions for the real-time scheduling based on a greedy algorithm; and Step 4, finding a solution to the moving-horizon Markov decision process model for the real-time scheduling of the multi-energy complementary micro-grids by using the Rollout algorithm based on the basic feasible solution from Step 3.

Abstract: Provided are a closed-loop system and a method for testing an intelligent alarm application of an integrated monitoring system. The system includes: a host computer and a slave computer, where the host computer and the slave computer perform downloading files and command interactions through an internal protocol, the host computer includes a visual signal configuration module, a scheduling protocol analysis and simulation module and an evaluation module, and the slave computer includes an intelligent electronic devices (IEDs) server simulation module.

Abstract: The present invention provides a method for producing a manganese-doped nickel molybdate electrode material including mixing a nickel salt solution with a manganese salt solution to form a mixture; adding a molybdate solution into the mixture and being subject to a thermal reaction; and obtaining the manganese-doped nickel molybdate electrode material after washing and drying of the reaction product. The nickel salt includes one or more of nickel nitrate, nickel chloride, and nickel acetate; the manganese salt includes one or more of manganese chloride, manganese nitrate, and manganese sulfate; and the molybdate includes one or more of sodium molybdate or ammonium molybdate. The present method utilizes a single reaction to produce a Mn-doped NiMoO4 electrode material, which does not require using nickel molybdate as an intermediate product. The method simplifies the preparation process and makes it easy to be adjusted, thereby improving the electrochemical properties of the electrode material.