Patents by Inventor Ling Kong
Ling Kong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250182070Abstract: A method may include: a distributed application on a digital banking and payment platform receiving, via an API, a reserve funds instruction from a first transaction party to hold a balance in a blockchain deposit account, the reserve funds instruction comprising a reserve hold amount; the distributed application validating the reserve funds instruction; the distributed application generating a blockchain transaction payload for the reserve funds instruction; the distributed application submitting the blockchain transaction payload to a smart contract that maintains a distributed ledger, validates that the blockchain deposit account has available funds sufficient for the reserve hold amount, and creates a reserve funds hold on the reserve hold amount in the blockchain deposit account; the distributed application receiving, in response to a successful reserve funds hold, a confirmation event from the smart contract; and the distributed application generating a first reserve identifier for the reserve funds holType: ApplicationFiled: November 27, 2024Publication date: June 5, 2025Inventors: Naveen MALLELA, Umar FAROOQ, Nelli ZALTSMAN, Joshua DANIEL, Sai Murali Krishna VALIVETI, Alyssa Rachel I Ling KONG, Aaron Paul DOYLE, Raunak RAJPURIA
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Publication number: 20240076362Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, humanized antibodies and antibody fragments, that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.Type: ApplicationFiled: May 1, 2023Publication date: March 7, 2024Inventors: Jeonghoon SUN, Wei-Hsien HO, Muhammad A. ALHAWAGRI, Philip Ling KONG, Herve RHINN, Hua LONG, Karpagam SRINIVASAN, Ananya MITRA, Daniel P. BERMINGHAM, Klaus-Dieter HEGER, Santiago Viveros SALAZAR, Francesca CIGNARELLA, Ilaria TASSI, Tina SCHWABE, Angie Grace YEE, Arnon ROSENTHAL
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Patent number: 11667699Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, humanized antibodies and antibody fragments, that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.Type: GrantFiled: July 30, 2020Date of Patent: June 6, 2023Assignee: Alector LLCInventors: Jeonghoon Sun, Wei-Hsien Ho, Muhammad A. Alhawagri, Philip Ling Kong, Herve Rhinn, Hua Long, Karpagam Srinivasan, Ananya Mitra, Daniel P. Bermingham, Klaus-Dieter Heger, Santiago Viveros Salazar, Francesca Cignarella, Ilaria Tassi, Tina Schwabe, Angie Grace Yee, Arnon Rosenthal
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Publication number: 20210079074Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, humanized antibodies and antibody fragments, that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.Type: ApplicationFiled: July 30, 2020Publication date: March 18, 2021Inventors: Jeonghoon SUN, Wei-Hsien HO, Muhammad A. ALHAWAGRI, Philip Ling KONG, Herve RHINN, Hua LONG, Karpagam SRINIVASAN, Ananya MITRA, Daniel P. BERMINGHAM, Klaus-Dieter HEGER, Santiago Viveros SALAZAR, Francesca CIGNARELLA, Ilaria TASSI, Tina SCHWABE, Angie Grace YEE, Arnon ROSENTHAL
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Publication number: 20210030923Abstract: The present application discloses a biological valve material which is a swim bladder derived biological valve material. The present application also discloses a method for preparing the biological valve material, includes: decellularizing a raw swim bladder; and cross-linking the decellularized swim bladder with a cross-linking agent. The present application also discloses use of the biological valve material, wherein the biological valve material is used for preparing one or more of a biological heart valve, a biological patch, and an artificial blood vessel. The present application also discloses a cross-linking agent for a bio-based material, including a cross-linking compound and an organic solvent. The cross-linking compound includes a polyphenol compound. The present application also discloses use of the cross-linking agent, wherein the cross-linking agent is used to cross-link the bio-based material after the decellularization treatment.Type: ApplicationFiled: June 24, 2019Publication date: February 4, 2021Inventors: ZHI-HONG WANG, JING LIU, XI-GANG LENG, DE-LING KONG, YI-BO QIN
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Patent number: 10166541Abstract: A microfluidic device and method comprises a rotatable substrate configured to be rotated at various angular velocities in order to accomplish a series of media exchanges with a sample chamber for containing a sample. A plurality of media reservoirs and waste reservoirs are connected to the sample chamber via channels forming capillary valves in which the capillary valves have varying burst frequencies of rotation of the substrate. The substrate can then be rotated through a series of angular velocities to automate media exchanges between the sample chamber and the respective media reservoirs and waste reservoirs. A pair of media reservoirs are located radially inward of the sample chamber and a pair of waste reservoirs are located radially outward of the sample chamber in an “X” configuration such that centrifugal forces cause fluid media to open the capillary valves and flow among the sample chamber, media reservoirs and waste reservoirs.Type: GrantFiled: December 9, 2015Date of Patent: January 1, 2019Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Lawrence Kulinsky, Ling Kong
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Patent number: 9993509Abstract: A method for increasing the expression of SIRT1 mRNA and/or decreasing the expression of SOCS3 mRNA, and especially for regulating blood glucose levels in a subject in need thereof is provided. The method comprises administering to the subject an effective amount of an active component selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound of formula (I), and combinations thereof: wherein X is H or C1-C3 alkyl; one of Y and Z is and the other one is H, OH or wherein when Y is Z is R1 to R13 are independently H or OH, and wherein, R1 to R3 are not simultaneously H; R8 and R9 are not simultaneously H.Type: GrantFiled: November 19, 2015Date of Patent: June 12, 2018Assignee: SINPHAR PHARMACEUTICAL CO., LTD.Inventors: Zwe-Ling Kong, Fan-Chi Ko, Ai-Ling Yeh
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Publication number: 20170099865Abstract: A method for enhancing sauce flavor including steps of: collection, dilution, denaturation, enzymolysis, enzyme deactivation, centrifugation, secondary enzymolysis, deodorization, Maillard reaction, seasoning, dosing and flexible sterilization of a raw material, salted duck egg white. The by-product, salted duck egg white, not fully used in the food processing industry is recycled as a raw material, which not only saves the cost but also can protect the environment. Hydrolyzed animal protein is obtained through double-enzyme fractional hydrolysis. The degree of hydrolysis is high. The obtained hydrolyzed protein contains no trichloropropanol and is relatively safe, and flavourzyme decomposes bitter peptide, to make the hydrolysate not taste bitter. Some yeast, cooking wine and essence with unique flavor are chosen. Each ingredient is in a reasonable proportion, and the obtained product is delicious and of mellow flavor.Type: ApplicationFiled: April 4, 2016Publication date: April 13, 2017Inventors: Min Zhang, Ling Kong, Yaping Liu, Weiming Zhang
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Publication number: 20160205987Abstract: The present invention is to provide a two-stage sterilization process for treating heat-resistant spores in a great burdock extract drink, which comprises the steps of sealing dried great burdock and water in a double-kettle pressure cooker; heating liquid mixture of great burdock and water to a first temperature range lower than or equal to 100° C. for at least a first duration during a first-stage sterilization; opening lid of the cooker and filtering out great burdock residue so that all that remains in the cooker is great burdock extract; resealing the cooker and heating the great burdock extract to a second temperature range higher than or equal to 120° C. for at least a second duration during a second-stage sterilization, and the pressure in the cooker during the second-stage sterilization is higher than that during the first-stage sterilization; so as to obtain the extract drink free of common bacteria and heat-resistant spores.Type: ApplicationFiled: April 27, 2015Publication date: July 21, 2016Applicant: BURDOCK BIOTECH TAIWAN CO., LTD.Inventors: Zwe-Ling KONG, Te-Chun TSOU, Shih-Chiang LEE
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Publication number: 20160167045Abstract: A microfluidic device and method comprises a rotatable substrate configured to be rotated at various angular velocities in order to accomplish a series of media exchanges with a sample chamber for containing a sample. A plurality of media reservoirs and waste reservoirs are connected to the sample chamber via channels forming capillary valves in which the capillary valves have varying burst frequencies of rotation of the substrate. The substrate can then be rotated through a series of angular velocities to automate media exchanges between the sample chamber and the respective media reservoirs and waste reservoirs. A pair of media reservoirs are located radially inward of the sample chamber and a pair of waste reservoirs are located radially outward of the sample chamber in an “X” configuration such that centrifugal forces cause fluid media to open the capillary valves and flow among the sample chamber, media reservoirs and waste reservoirs.Type: ApplicationFiled: December 9, 2015Publication date: June 16, 2016Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Lawrence Kulinsky, Ling Kong
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Patent number: 9339522Abstract: A method for increasing the expression of SIRT1 mRNA and/or decreasing the expression of SOCS3 mRNA, and especially for regulating blood glucose levels in a subject in need thereof is provided. The method comprises administering to the subject an effective amount of an active component selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound of formula (I), and combinations thereof: wherein X is H or C1-C3 alkyl; one of Y and Z is and the other one is H, OH or wherein when Y is Z is R1 to R13 are independently H or OH, and wherein, R1 to R3 are not simultaneously H; R8 and R9 are not simultaneously H.Type: GrantFiled: May 28, 2014Date of Patent: May 17, 2016Assignee: SINPHAR PHARMACEUTICAL CO., LTD.Inventors: Zwe-Ling Kong, Fan-Chi Ko, Ai-Ling Yeh
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Publication number: 20160082064Abstract: A method for increasing the expression of SIRT1 mRNA and/or decreasing the expression of SOCS3 mRNA, and especially for regulating blood glucose levels in a subject in need thereof is provided. The method comprises administering to the subject an effective amount of an active component selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound of formula (I), and combinations thereof: wherein X is H or C1-C3 alkyl; one of Y and Z is and the other one is H, OH or wherein when Y is Z is R1 to R13 are independently H or OH, and wherein, R1 to R3 are not simultaneously H; R8 and R9 are not simultaneously H.Type: ApplicationFiled: November 19, 2015Publication date: March 24, 2016Inventors: Zwe-Ling KONG, Fan-Chi KO, Ai-Ling YEH
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Publication number: 20140357581Abstract: A method for increasing the expression of SIRT1 mRNA and/or decreasing the expression of SOCS3 mRNA, and especially for regulating blood glucose levels in a subject in need thereof is provided. The method comprises administering to the subject an effective amount of an active component selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound of formula (I), and combinations thereof: wherein X is H or C1-C3 alkyl; one of Y and Z is and the other one is H, OH or wherein when Y is Z is R1 to R13 are independently H or OH, and wherein, R1 to R3 are not simultaneously H; R8 and R9 are not simultaneously H.Type: ApplicationFiled: May 28, 2014Publication date: December 4, 2014Applicant: SINPHAR PHARMACEUTICAL CO., LTD.Inventors: Zwe-Ling KONG, Fan-Chi KO, Ai-Ling YEH
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Patent number: 8712569Abstract: A system for determining a list of potential lots for consolidation is presented. The system includes a module having a database and an input for receiving an event occurrence. The database may include a set of consolidation rules. The module, upon receiving the event occurrence, retrieves the consolidation rules and initiates a consolidation analysis to determine the list of potential lots for consolidation based on the consolidation rules.Type: GrantFiled: June 27, 2008Date of Patent: April 29, 2014Assignee: GLOBALFOUNDRIES Singapore Pte. Ltd.Inventors: Jimmy Lay Kuan Goh, Meng Yong Quek, Siow Ling Kong
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Publication number: 20130272642Abstract: A rotary connection apparatus comprising a bottom bracket, a top bracket rotatably connected to the bottom bracket, an annular spacer and a plurality of balls. The spacer and the balls are received between the bottom bracket and the top bracket. A thickness of the spacer is less than a diameter of the balls, and the spacer includes a plurality of holding holes, each holding hole has two openings exposed at opposite surfaces of the spacer, and a diameter of each of the openings is less than that of the balls, and a diameter of a central portion of each holding hole is equal to the diameter of the balls; each of the holding holes accommodates one corresponding ball, and each ball has opposite end portions protruding out of the spacer. A spacer is also provided.Type: ApplicationFiled: April 9, 2013Publication date: October 17, 2013Applicants: HON HAI PRECISION INDUSTRY CO., LTD., HONG FU JIN PRECISION INDUSTRY (ShenZhen) CO., LTD .Inventors: GUO-FENG LI, YA-PING TENG, MENG-HUA HE, LI-HUA DING, HUI YE, LING-KONG WANG, CHUN-CHE YEN, FENG-HSING HSIEH
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Publication number: 20110262564Abstract: Novel chemopreventive and chemotherapeutic cancer treatment method using elemental selenium nanoparticles. Cancer cells, especially androgen dependent prostate cancers are exposed to selenium from elemental selenium nanoparticle treatment, and apoptosis is induced in the cancer cells.Type: ApplicationFiled: June 18, 2010Publication date: October 27, 2011Inventors: Xueyun Gao, Ling Kong
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Publication number: 20110186293Abstract: A method and apparatus to treat a subterranean formation including introducing a fluid comprising degradable material into a wellbore, contacting a surface of the wellbore with the fluid, and stimulating a surface of a subterranean formation, wherein the contacting the wellbore surface and stimulating the formation occur over a time period that is tailored by the properties of the degradable material. In some embodiments, the properties of the degradable material include a chemical composition, a surface area, a geometric shape of a particle of the material, a concentration of the material in the fluid, a density of the material, a dimension of a particle of the material, or a combination thereof.Type: ApplicationFiled: December 17, 2010Publication date: August 4, 2011Inventors: M. Nihat Gurmen, Daniel Kalinin, Ryan Hellman, Oscar Bustos, J.Ernest Brown, Michael J. Fuller, Ling Kong Teng
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Patent number: D1081426Type: GrantFiled: May 8, 2024Date of Patent: July 1, 2025Inventor: Ling Kong
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Patent number: D1081427Type: GrantFiled: August 17, 2024Date of Patent: July 1, 2025Assignee: Shenzhen Hansway Technology Co., Ltd.Inventor: Ling Kong
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Patent number: D1081428Type: GrantFiled: September 28, 2024Date of Patent: July 1, 2025Assignee: Shenzhen Hansway Technology Co., Ltd.Inventor: Ling Kong