Abstract: The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.

Abstract: The invention encompasses compositions and methods for selecting aptamers.

Abstract: The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.

Abstract: A method of improving energy consumption and/or melt quality of injection molding or extrusion machine can include controlling energy input to the melt from screw drive and heat sources. One or more sensors can measure a present value of at least one process parameter associated with the melt. A control algorithm can compare the present value of melt with a set value. If the present value deviates from the set value by more than a predetermined amount, the set value of at least one operating parameter can be adjusted. The algorithm can determine energy transferred to melt material from thermal and mechanical sources, and adjust set values to optimize energy consumption. Process parameters can include melt temperature, melt quality characterized value, prospective throughput or injection cycle time, or prospective energy consumption value. Operating parameters can include barrel heating temperature, screw rotational speed, screw plasticizing back pressure, screw injection speed or screw injection pressure.

Abstract: The present invention encompasses a method for detecting a target comprising a repeating epitope.

Abstract: A method of improving energy consumption and/or melt quality of injection molding or extrusion machine can include controlling energy input to the melt from screw drive and heat sources. One or more sensors can measure a present value of at least one process parameter associated with the melt. A control algorithm can compare the present value of melt with a set value. If the present value deviates from the set value by more than a predetermined amount, the set value of at least one operating parameter can be adjusted. The algorithm can determine energy transferred to melt material from thermal and mechanical sources, and adjust set values to optimize energy consumption or improve melt quality. Process parameters can include melt temperature, melt quality characterized value, prospective throughput or injection cycle time, or prospective energy consumption value.

Abstract: The invention generally provides molecular biosensors. The molecular biosensors are useful in competition assays to detect the presence of a target molecule.

Abstract: The invention generally provides molecular biosensors. The molecular biosensors are useful in competition assays to detect the presence of a target molecule.

Abstract: The present invention provides a vaccine which is capable of inhibiting the growth and formation of tumors which can express an endogenous tumor specific protein. Also disclosed are methods of administering the vaccine to a subject bearing a tumor whose formation and growth is inhibited by the vaccine.

Abstract: The present invention provides a vaccine which is capable of inhibiting the growth and formation of tumors which can express an endogenous tumor specific protein. Also disclosed are methods of administering the vaccine to a subject bearing a tumor whose formation and growth is inhibited by the vaccine.