Abstract: An electronic device includes a battery module, a battery connector and a controller is provided. The battery connector includes a first connector and a second connector. The first connector is installed on the battery module and includes a first metal component and an enable pin. The first metal component is disposed on a housing of the first connector and is coupled to the enable pin. The second connector includes a second metal component, a detection pin and a ground pin. The second metal component is disposed on a housing of the second connector. The detection pin is coupled to the second metal component. The ground pin is coupled to a ground potential and its position corresponds to the position of the enable pin. The controller determines a connection status of the first connector and the second connector according to an external signal on the detection pin.

Abstract: Systems and methods for computing time series predictions are provided, including a two-stage classifier-and-regressor processor. The classifier is trained on the complete data set while the regressor is trained on a pruned dataset. The classifier includes an Extreme Gradient Boosting classifier. The regressor includes an attention mechanism and a Long Short-Term Memory (LSTM) neural network. For a series of successive time period computations, a current output of the LSTM neural network is recursively fed back as an input to the attention mechanism for a subsequent time period computation. The output of the regressor is scaled by the output of the classifier to adjust for overfitting caused by the pruned training dataset.

Abstract: A monolithic carbon foam formed of fused onion-like carbon (OLC) nanoparticles, in which the monolithic carbon foam contains interconnected pores, has a volumetric micropore surface area of 200 m2/cc-600 m2/cc, and has an electrical conductivity of 20 s/cm-140 s/cm. Also disclosed are electrodes and energy storage devices constructed therefrom.

Abstract: A tunable laser for a transceiver includes a silicon photonics substrate, first and second patterned regions each being defined in the substrate a step lower than a flat surface region of the substrate, first and second laser diode chips arranged in the first and second patterned regions, the patterned regions being configured to align the gain regions of the first and second laser diode chips with integrated couplers formed in the substrate adjacent to the first and second patterned regions to facilitate flip-bonding the first and second laser diode chips within the patterned regions, and a tuning filter coupled to the first laser diode chip and the second laser diode chip via the integrated couplers. The tuning filter is configured to receive laser light from each of the first and second laser diode chips and generate a laser output having a gain determined by each of the gain regions.

Abstract: Embodiments of the technology described herein are based, in part, upon the discovery that NETosis, the formation of neutrophil extracellular traps (NETs) is increased in wounds, in organ fibrosis and in subjects with diabetes. Accordingly, methods for treating wounds, fibrosis and NET associated complications in diabetes are provided. The methods comprise administrating a therapeutically effective amount of at least one anti-NET compound to a subject in need of treatment, e.g. a PAD 4 inhibitor, a DNase, a histone-degrading enzyme; an inhibitor of chromatin decondensation; an antibody against a component of a NET; an inhibitor of NET release, a protease inhibitor, or an elastase inhibitor.

Abstract: The present invention relates to compositions comprising an anionic polymer, such as hyaluronate or alginate, a cation such as calcium, an anion such as phosphate, and nucleic acids such as siRNA for the SPARC gene. The compositions are used for delivery of nucleic acids to cells to thereby regulate gene expression and treat diseases such as ocular fibrosis disorders.

Abstract: An eyewear frame having at least one frame component including a stimuli-responsive polymer is provided. The at least one frame component has a physical property which is reversibly changeable in response to a stimulus of non-thermal origin applied to the stimuli-responsive polymer. An eyewear including the eyewear frame, and a method of adjusting the eyewear frame are also provided.

Abstract: The present invention relates to the use of valproic acid for reducing post-operative scarring following a glaucoma surgery. In one embodiment, the glaucoma surgery is glaucoma filtering surgery, which comprises creating a subconjunctival bleb. In another embodiment, the glaucoma surgery is minimally invasive glaucoma surgery (MIGS), which comprises implanting a glaucoma tube shunt under a subconjunctival space.

Abstract: Multi-layer contact patches, as well as related apparatus, kits, systems, and methods, enable improved allergen testing and diagnosis. Multi-layer contact patches include a shield layer releasably coupled to an adhesive layer. The adhesive layer at least partially defines and is fixably coupled to an allergen complex layer. The allergen complex layer defines a plurality of allergen complex cavities. At least a subset of the allergen complex cavities include an allergen complex positioned therein, each allergen complex comprising an absorbent matrix and an allergen.

Abstract: Multi-layer contact patches, as well as related apparatus, kits, systems, and methods, enable improved allergen testing and diagnosis. Multi-layer contact patches include a shield layer releasably coupled to an adhesive layer. The adhesive layer at least partially defines and is fixably coupled to an allergen complex layer. The allergen complex layer defines a plurality of allergen complex cavities. At least a subset of the allergen complex cavities include an allergen complex positioned therein, each allergen complex comprising an absorbent matrix and an allergen.

Abstract: The disclosure provides a method for treating and/or preventing graft rejection with A Disintegrin And Metalloproteinase with Thrombospondin type 1 motif, member-13 (ADAMTS13). The disclosure provides a method for increasing ADAMTS13-mediated von Willebrand factor (VWF) cleavage in a subject that received a graft by administering ADAMTS13. The disclosure also provides a method of determining the likelihood that a subject will rejection a graft.

Abstract: A makeup fluid management and supply device and method are provided. The method includes the steps of: receiving a cosmetic style template sent from a user device; selecting a makeup bottle by the control module in accordance with a makeup application step of the cosmetic style template and moving the makeup bottle to a using position by the driving module; reading a label information of the makeup bottle; sending the label information to the management unit so as to perform a validation procedure on the makeup bottle; rotating, in response to a positive validation result, the makeup bottle by the driving module so as to perform a makeup fluid mixing procedure on the makeup bottle; and driving, by the driving module, the makeup bottle to move in a first direction until the makeup bottle is squeezed so as to obtain a makeup fluid of the makeup bottle.

Abstract: A tunable laser for a transceiver includes a silicon photonics substrate, first and second patterned regions each being defined in the substrate a step lower than a flat surface region of the substrate, first and second laser diode chips arranged in the first and second patterned regions, the patterned regions being configured to align the gain regions of the first and second laser diode chips with integrated couplers formed in the substrate adjacent to the first and second patterned regions to facilitate flip-bonding the first and second laser diode chips within the patterned regions, and a tuning filter coupled to the first laser diode chip and the second laser diode chip via the integrated couplers. The tuning filter is configured to receive laser light from each of the first and second laser diode chips and generate a laser output having a gain determined by each of the gain regions.

Abstract: Embodiments of the technology described herein are based, in part, upon the discovery that NETosis, the formation of neutrophil extracellular traps (NETs) is increased in wounds, in organ fibrosis and in subjects with diabetes. Accordingly, methods for treating wounds, fibrosis and NET associated complications in diabetes are provided. The methods comprise administrating a therapeutically effective amount of at least one anti-NET compound to a subject in need of treatment, e.g. a PAD 4 inhibitor, a DNase, a histone-degrading enzyme; an inhibitor of chromatin decondensation; an antibody against a component of a NET; an inhibitor of NET release, a protease inhibitor, or an elastase inhibitor.

Abstract: A monolithic carbon foam formed of fused onion-like carbon (OLC) nanoparticles, in which the monolithic carbon foam contains interconnected pores, has a volumetric micropore surface area of 200 m2/cc-600 m2/cc, and has an electrical conductivity of 20 cm- 140 S/cm. Also disclosed are a fractal carbon foam prepared from the monolithic carbon foam, methods of preparing both foams, and supercapacitors constructed therefrom. Specifically, the methods of preparing the foams comprising, inter alia, spark plasma sintering the OLC nanoparticles at a pressure of 30 MPa-1000 MPa and a temperature of 300° C.-800° C. for 2 seconds-30 minutes.

Abstract: A tunable laser device based on silicon photonics includes a substrate configured with a patterned region comprising one or more vertical stoppers, an edge stopper facing a first direction, a first alignment feature structure formed in the patterned region along the first direction, and a bond pad disposed between the vertical stoppers. Additionally, the tunable laser includes an integrated coupler built in the substrate located at the edge stopper and a laser diode chip including a gain region covered by a P-type electrode and a second alignment feature structure formed beyond the P-type electrode. The laser diode chip is flipped to rest against the one or more vertical stoppers with the P-type electrode attached to the bond pad and the gain region coupled to the integrated coupler. Moreover, the tunable laser includes a tuning filter fabricated in the substrate and coupled via a wire waveguide to the integrated coupler.

Abstract: A system for board-to-board interconnect is described herein. The system includes a first printed circuit board (PCB) having a first recess along a first edge of the first PCB that exposes a first solder pad on a layer of the first PCB. The system also includes a second PCB having a second recess along a second edge of the second PCB that exposes a second solder pad on a layer of the second PCB. The second recess is complementary to the first recess to allow the first PCB to mate with the second PCB. The first solder pad is aligned with the second solder pad when the first PCB is mated with the second PCB. The system additionally includes an assembly configured to electronically couple the first solder pad with the second solder pad.

Abstract: A monolithic carbon foam formed of fused onion-like carbon (OLC) nanoparticles, in which the monolithic carbon foam contains interconnected pores, has a volumetric micropore surface area of 200 m2/cc-600 m2/cc, and has an electrical conductivity of 20 s/cm-140 s/cm. Also disclosed are electrodes and energy storage devices constructed therefrom.

Abstract: This method for predicting evolution over time of at least one vision-related parameter of at least one person includes: obtaining successive values for the person, respectively corresponding to repeated measurements over time of at least one parameter of a first predetermined type for the person; predicting by at least one processor the evolution over time of the vision-related parameter of the person from the obtained successive values for the person, by using a prediction model associated with a group of individuals; the predicting including associating at least part of the successive values for the person with the predicted evolution over time of the vision-related parameter of the person, the associating including jointly processing the successive values associated with the same parameter of the first predetermined type. The predicted evolution depends differentially on each of the jointly processed values.

Abstract: This method for building a prediction model for predicting evolution over time of at least one vision-related parameter of at least one person includes: obtaining successive values respectively corresponding to repeated measurements over time of at least one parameter of a first predetermined type for at least one member of a group of individuals; obtaining evolution over time of the vision-related parameter(s) for the member(s) of the group of individuals; building by at least one processor the prediction model, including associating at least part of the successive values with the obtained evolution over time of the vision-related parameter(s) for the member(s) of the group of individuals, the associating including jointly processing the at least part of the successive values associated with a same one of the parameter(s) of the first predetermined type. The prediction model depends differentially on each of the jointly processed values.