Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells; chimeric antigen receptors (CARs); immune cells; pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.

Abstract: A packet forwarding method, apparatus, and system, and a computer-readable storage medium are disclosed, and pertain to the field of communication technologies. After receiving a packet sent by a second device, a first device determines a target service node based on indication information and an application service identifier that are in the packet, where a service capability of the target service node matches the indication information, and a target application service corresponding to the application service identifier is deployed in the target service node. Then, the first device sends the packet to the target service node. The indication information is carried in the packet sent by the device, so that a forwarding device can send the packet to a service node whose service capability matches the indication information. In this way, differentiated application services are provided for devices of different levels, and flexibility of task scheduling is high.

Abstract: An electronic educational toy for children, a toy body comprises a body, a rotating block group, a control module and a display module, a setting module is disposed on the body to select different game modes, the rotating block group comprises a plurality of rotating blocks, each of the plurality of rotating blocks is disposed with a plurality of display screens, the plurality of display screens of the plurality of rotating blocks currently in a same plane as the display module is used as an exhibition surface, the control module generates a corresponding data group according to a selected game mode, the plurality of display screens of the plurality of rotating blocks display the corresponding data group, the control module judges whether content currently displayed on the exhibition surface of the plurality of rotating blocks is correct, and the display module displays the content in real time.

Abstract: This application provides a communication method and a communication apparatus. The method includes: sending a registration request message; receiving a registration accept message, where the registration accept message carries first indication information, and the first indication information indicates to return a registration complete message after the registration accept message is received; and sending the registration complete message based on the registration accept message. This method helps ensure that an information element in a registration accept message between a network side and a terminal side is aligned, so that the terminal can perform normal communication. In addition, first indication information is carried to enable the terminal to return a registration complete message. This further helps improve system compatibility.

Abstract: A robotic interventional device control system includes a first hub assembly coupled to a first interventional device and including a first proximal end and a first distal end; and a second hub assembly coupled to a second interventional device and positioned distal to the first hub assembly. The second hub assembly includes a second proximal end and a second distal end. The system includes a sensor system configured to detect a first position of the first hub assembly and a second position of the second hub assembly; and one or more hardware processors configured to generate a user interface. The user interface includes a drive table window including a first representation of the first hub assembly and a second representation of the second hub assembly.

Abstract: A packet forwarding method. In this method, a forwarding node receives a packet, obtains a target service resource status advertised by each service node in a plurality of service nodes, selects a target service node from the plurality of service nodes based on the target service resource status advertised by the service node, and forwards the packet to the target service node. In other words, the forwarding node can sense a service resource status advertised by the service node, and the service resource status can indicate a resource usage status of a service resource managed by the service node. An actual processing capability of the service node can be sensed based on the resource usage status.

Abstract: Embodiments of this application provide a communication method and a communication apparatus. The communication method includes: A network device obtains user subscription information, where the user subscription information indicates that MPS information of a terminal device changes; and the network device sends a first message to the terminal device, where the first message is for triggering the terminal device to re-register, so that the terminal device updates an MPS indicator in a re-registration process, and the network device supports triggering, by using a CUC message, the terminal device to update the MPS indicator. According to the communication method and the communication apparatus provided in embodiments of this application, when the MPS information of the terminal device changes, even if the terminal device does not support updating the MPS indicator by using the CUC message, the terminal device can be triggered to update the MPS indicator in a re-registration manner.

Abstract: The present disclosure provides scaffolds and antibody-drug conjugates (ADCs) comprising a stimulator of interferon genes (STING). The present disclosure also provides uses of the ADCs in treatment, e.g., treatment of cancer.

Abstract: The present disclosure discloses a liquid crystal display panel and a compensation method thereof. The compensation method firstly acquires a plurality of consecutive and alternating odd-numbered frame grayscale data and even-numbered frame grayscale data, then determines a minimum grayscale difference, and determines a gamma voltage difference corresponding to the grayscale difference according to a curve of a relation between grayscales and gamma voltages, followed by obtaining a correction value for a common voltage based on the gamma voltage difference. The flicker phenomena can be improved by adjusting the common voltage only once with the correction value.

Abstract: The present disclosure provides scaffolds and antibody-drug conjugates (ADCs) comprising a stimulator of interferon genes (STING). The present disclosure also provides uses of the ADCs in treatment, e.g., treatment of cancer.

Abstract: The present application discloses a display compensation method and a liquid crystal display device. The display compensation method adjusts backlight brightness corresponding to backlight partitions by a backlight compensation table, therefore can roughly adjust a brightness difference of the display panel, and can also improve a contrast of a screen image, which advantages for guaranteeing grayscale transition continuity of a screen image; also, adjusting by a display compensation table adjusts grayscale data corresponding to the display partitions can achieve fine adjustment of the brightness difference of the display panel such that uniformity of the display brightness can be further increased.

Abstract: Provided herein are compositions comprising trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more HIV target proteins or one or more T-cell receptors, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation and wherein a second pair of polypeptides forming the binding protein possess a single variable domain. Also provided herein are methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins for the treatment and/or prevention of HIV/AIDS.

Abstract: The present disclosure provides a display compensation method for a display panel, a method for generating a compensation data table, and a display device. A first display luminance corresponding to a first to-be-compensated sub-pixel set and a second display luminance corresponding to a second to-be-compensated sub-pixel set are respectively compensated by corresponding compensation data tables in different viewing angles. A plurality of first compensation data tables corresponding to the first viewing angle and a plurality of second compensation data tables corresponding to the second viewing angle are used to compensate for the first to-be-compensated sub-pixel set and the second to-be-compensated sub-pixel sets adjacent with each other.

Abstract: This application discloses a packet forwarding method, an apparatus, and a system, and belongs to the field of communication technologies. The method includes: A first node receives a first packet. The first node sends a second packet to a second node based on the first packet, where a source address of the second packet is obtained by translating a source address of the first packet, a destination address of the second packet is a destination address of the first packet, a packet payload of the second packet is a packet payload of the first packet, the second packet further includes a session identifier, and the session identifier is used by the second node to forward the second packet.

Abstract: Provided herein are trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation, and wherein and a second pair of polypeptides possess a single variable domain forming a single antigen binding site. In some embodiments, the binding proteins comprise a binding site that binds a CD28 polypeptide, a binding site that binds a CD3 polypeptide, and a binding site that binds a third polypeptide, such as a tumor target protein. In some embodiments, the binding proteins comprise four polypeptide chains that form three antigen binding sites that specifically bind one or more HIV target proteins. The disclosure also relates to methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins.

Abstract: Provided herein are trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation, and wherein and a second pair of polypeptides possess a single variable domain forming a single antigen binding site. In some embodiments, the binding proteins comprise a binding site that binds a CD28 polypeptide, a binding site that binds a CD3 polypeptide, and a binding site that binds a third polypeptide, such as a tumor target protein. In some embodiments, the binding proteins comprise four polypeptide chains that form three antigen binding sites that specifically bind one or more HIV target proteins. The disclosure also relates to methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins.

Abstract: The present invention discloses a method for cultivating a plant resistant to gray leaf spot. The proteins provided by the present invention are obtained from corn and named as ZMPK protein, and are the proteins represented by SEQ ID NO: 2, SEQ ID NO: 4, SEQ ID NO: 7 or SEQ ID NO: 9 in the sequence list. Nucleic acid molecules encoding the ZMPK proteins are also within the scope of the present invention. The invention further sets forth a method for preparing a transgenic plant, comprising the step of: introducing the nucleic acid molecules into a starting plant to obtain the transgenic plant with reduced resistance to gray leaf spot. The invention further sets forth a method for preparing a transgenic plant, comprising the step of: knocking out or inhibiting the expression of the nucleic acid molecules in a starting plant to obtain the transgenic plant with increased resistance to gray leaf spot. The present invention is of great application value to the breeding of corn resistant to gray leaf spot.

Abstract: Subsequent to initializing a frame buffer associated with a menu, an information handling system decomposes content of the frame buffer into a text space, a foreground space, and a background space. The system navigates the menu to a key node using a control key, wherein the key node includes an expected text and an expected attribute. The system also matches a text and an attribute of a current element to the expected text and the expected attribute, wherein the text is from the text space, and wherein the attribute is a foreground color from the foreground space or a background color from the background space.

Abstract: This application provides a multi-path data flow steering method and an apparatus, and relates to the field of communication technologies. The method includes: a communication device obtains a data flow, where the data flow includes a first group of protocol data unit sets and a second group of protocol data unit sets. The communication device determines a steering mode that is based on each group of protocol data unit sets, and sends the first group of protocol data unit sets on a first path. The communication device sends the second group of protocol data unit sets on a second path.

Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) that bind to HIV proteins and have certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells; chimeric antigen receptors (CARs); immune cells; pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes in HIV.