Abstract: Provided is an antigen-binding molecule, particularly a domain-engineered antibody, wherein at least one constant region domain CH1/CL of the antibody is replaced by a Titin T-chain/Obscurin-O chain.

Abstract: Disclosed is a three-dimensional low-dose PET reconstruction method based on deep learning. The method comprises the following steps: back projecting low-dose PET raw data to the image domain to maintain enough information from the raw data; selecting an appropriate three-dimensional deep neural network structure to fit the mapping between the back projection of the low-dose PET and a standard-dose PET image; after learning from the training samples the network parameters are fixed, realizing three-dimensional PET image reconstruction starting from low-dose PET raw data, thereby obtaining a low-dose PET reconstructed image which has a lower noise and a higher resolution compared with the traditional reconstruction algorithm and image domain noise reduction processing.

Abstract: The present invention generally relates to nanowires. In one aspect, the present invention is generally directed to systems and methods of individually addressing nanowires on a surface, e.g., that are substantially upstanding or vertically-oriented with respect to the surface. In some cases, one or more nanowires may be individually addressed using various integrated circuit (“IC”) technologies, such as CMOS. For example, the nanowires may form an array on top of an active CMOs integrated circuit.

Abstract: Embodiments of the present disclosure discloses a method and a device for connecting apparatuses, apparatuses and storage medium, which relates to the field of communication. The method includes: determining whether the first apparatus stores an identifier of a target-type apparatus; when the first apparatus stores the identifier of the target-type apparatus, transmitting triggering information to a second apparatus, wherein the triggering information is used to trigger the second apparatus to transmit a connection request, a type associated with the second apparatus is the target type, and the second apparatus is connected with the first apparatus through a wired input line; receiving the connection request transmitted by the second apparatus; and establishing a wireless connection with the second apparatus based on the connection request. Therefore, the embodiments of the present disclosure can automatically connect apparatuses and improve an efficiency of connecting apparatuses.

Abstract: An operation mode switching control method, an electronic device, and a computer-readable storage medium are provided. The electronic device includes a processor and a camera. An image sensor in the camera includes at least two operation modes. The operation mode switching control method includes: The processor sends a signal to the image sensor through an I2C interface, where the signal is used to control the image sensor to run in an operation mode corresponding to the signal.

Abstract: This disclosure relates to scaffolds for inducing antibody responses against antigenic sites. In certain embodiments, this disclosure relates to compositions and methods using a filovirus sGP as a scaffold for inducing antibody responses against antigenic sites in foreign pathogens. In certain embodiments, this disclosure relates to compositions and methods using a filovirus sGP as a scaffold for inducing antibody responses against a virus to produce a viral vaccine.

Abstract: An operation mode switching control method, an electronic device, and a computer-readable storage medium are provided. The electronic device includes a processor and a camera. An image sensor in the camera includes at least two operation modes. The operation mode switching control method includes: The processor sends a signal to the image sensor through an I2C interface, where the signal is used to control the image sensor to run in an operation mode corresponding to the signal.

Abstract: A polypeptide and an application thereof in bone repair are provided. An amino acid sequence of the polypeptide provided by the invention is shown as SEQ ID NO: 1. The invention further discloses use of the polypeptide GS18 in bone injury and/or bone repair. Furthermore, the invention further discloses an application of the polypeptide GS18 as well as a polypeptide scaffold for bone repair. The polypeptide of the invention demonstrates the ability to translocate ?-catenin into the nucleus and induce the expression of secreted protein osteocalcin in vivo. In vitro, the polypeptide facilitates the osteogenic differentiation of osteogenesis-oriented BMSCs (pre-osteoblasts thereby promoting the process of bone repair.

Abstract: A polypeptide and an application thereof in bone repair are provided. An amino acid sequence of the polypeptide provided by the invention is shown as SEQ ID NO: 1. The invention further discloses use of the polypeptide GS18 in bone injury and/or bone repair. Furthermore, the invention further discloses an application of the polypeptide GS18 as well as a polypeptide scaffold for bone repair. The polypeptide of the invention demonstrates the ability to translocate ?-catenin into the nucleus and induce the expression of secreted protein osteocalcin in vivo. In vitro, the polypeptide facilitates the osteogenic differentiation of osteogenesis-oriented BMSCs (pre-osteoblasts thereby promoting the process of bone repair.

Abstract: A sensory evaluation method for spectral data of mainstream smoke includes: performing a data enhancement on spectral data of mainstream smoke of a plurality of cigarettes; extracting a shallow spectral characteristic from the spectral data of the mainstream smoke of each cigarette; obtaining a shallow sensory quality result of the spectral data of the mainstream smoke of each cigarette based on the spectral data of the mainstream smoke of each cigarette and the shallow spectral characteristic; extracting deep spatial characteristics from the spectral data of the mainstream smoke of each cigarette; obtaining a deep sensory quality result based on the spectral data of the mainstream smoke of each cigarette and the deep spatial characteristics; obtaining a comprehensive sensory quality result according to the shallow sensory quality result and the deep sensory quality result. The sensory evaluation method achieves accurate screening of unknowns in the mainstream smoke.

Abstract: A three-dimensional electrode-ozone oxidation-electrocatalytic membrane coupled wastewater treatment device, including a circulating fluidized bed reactor. The circulating fluidized bed reactor includes a funnel-shaped internal, a truncated cone, a fiber ball filter, a gas-liquid distribution plate, an inner cylinder, an intermediate cylinder and an outer cylinder. The inner cylinder, the intermediate cylinder and the outer cylinder are coaxial. The inner cylinder is an electrocatalytic membrane assembly; the intermediate cylinder is a gas diffusion electrode; and the outer cylinder is a stainless-steel mesh. A particle electrode is filled between the intermediate cylinder and the outer cylinder, and between the intermediate cylinder and the inner cylinder. The intermediate cylinder is connected to a negative electrode. The inner cylinder and the outer cylinder are connected to a positive electrode. A wastewater treatment method using the device is also provided herein.

Abstract: A three-dimensional electrode-ozone oxidation-electrocatalytic membrane coupled wastewater treatment device, including a circulating fluidized bed reactor. The circulating fluidized bed reactor includes a funnel-shaped internal, a truncated cone, a fiber ball filter, a gas-liquid distribution plate, an inner cylinder, an intermediate cylinder and an outer cylinder. The inner cylinder, the intermediate cylinder and the outer cylinder are coaxial. The inner cylinder is an electrocatalytic membrane assembly; the intermediate cylinder is a gas diffusion electrode; and the outer cylinder is a stainless-steel mesh. A particle electrode is filled between the intermediate cylinder and the outer cylinder, and between the intermediate cylinder and the inner cylinder. The intermediate cylinder is connected to a negative electrode. The inner cylinder and the outer cylinder are connected to a positive electrode. A wastewater treatment method using the device is also provided herein.

Abstract: A sensory evaluation method for spectral data of mainstream smoke includes: performing a data enhancement on spectral data of mainstream smoke of a plurality of cigarettes; extracting a shallow spectral characteristic from the spectral data of the mainstream smoke of each cigarette; obtaining a shallow sensory quality result of the spectral data of the mainstream smoke of each cigarette based on the spectral data of the mainstream smoke of each cigarette and the shallow spectral characteristic; extracting deep spatial characteristics from the spectral data of the mainstream smoke of each cigarette; obtaining a deep sensory quality result based on the spectral data of the mainstream smoke of each cigarette and the deep spatial characteristics; obtaining a comprehensive sensory quality result according to the shallow sensory quality result and the deep sensory quality result. The sensory evaluation method achieves accurate screening of unknowns in the mainstream smoke.

Abstract: A winch includes a coupling A, a coupling B, a rectangular spring, a gear wheel, a gear rack, a friction ring, and a transmission shaft, etc. By increasing the distance between the adjacent internal teeth of the two-stage planet carrier, it ensures that the three-stage sun gear can be smoothly inserted into the two-stage planet carrier even if the elasticity of spring A is reduced, such that the engagement width between the three-stage sun gear and the two-stage planet carrier can reach the normal requirements. With the design of sliding gear ring and spring C, it can greatly reduce the phenomenon of mis-engagement when the external teeth of the three-stage sun gear enter the internal teeth spacing of the two-stage planet carrier, protect the teeth integrity of the three-stage sun gear and the two-stage planet carrier.

Abstract: A winch includes a coupling A, a coupling B, a rectangular spring, a gear wheel, a gear rack, a friction ring, and a transmission shaft, etc. By increasing the distance between the adjacent internal teeth of the two-stage planet carrier, it ensures that the three-stage sun gear can be smoothly inserted into the two-stage planet carrier even if the elasticity of spring A is reduced, such that the engagement width between the three-stage sun gear and the two-stage planet carrier can reach the normal requirements. With the design of sliding gear ring and spring C, it can greatly reduce the phenomenon of mis-engagement when the external teeth of the three-stage sun gear enter the internal teeth spacing of the two-stage planet carrier, protect the teeth integrity of the three-stage sun gear and the two-stage planet carrier.

Abstract: A composite pipe, including, successively, from the inside out in the radial direction of the composite pipe: an inner liner layer; a reinforced layer; and an outer protective layer. The reinforced layer includes a bamboo fiber reinforced layer and a straw reinforced layer. The bamboo fiber reinforced layer includes a plurality of bamboo strip layers. Each bamboo strip layer includes winding bamboo strips. The straw reinforced layer includes a plurality of straw layers. Each straw layer includes winding stems of straw.