Patents by Inventor Lingbing ZENG

Lingbing ZENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyprinid herpesvirus II-sensitive brain tissue cell line of and establishing method and use thereof
    Patent number: 9598671
    Abstract: The present invention discloses a cyprinid herpesvirus II-sensitive brain tissue cell line of Carassius auratus gibelio and establishing method and use thereof. The cell line is deposited in China Center for Type Culture Collection under an accession number of CCTCC No: C2013179. The brain tissue cell line of Carassius auratus gibelio is in good growth state and sensitive to CyHV-2 that is presently hardly cultured with ordinary fish cell lines. After six passages of CyHV-2 in GiCB cells, viral nucleic acid can still be detected and a cytopathic effect is stable. When ultrathin microscopic sections are prepared from cells having the cytopathic effect, considerable mature CyHV-2 virions and their replication process can be observed in GiCB cells. The construction method of the brain tissue cell line of Carassius auratus gibelio of the present invention has high repeatability, scientific and reasonable conditions.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: March 21, 2017
    Assignee: YANGTZE RIVER FISHERIES RESEARCH INSTITUTE, CHINESE ACADEMY OF FISHERY SCIENCES
    Inventors: Jie Ma, Lingbing Zeng, Nan Jiang, Qian Chen, Hui Zhao
  • CYPRINID HERPESVIRUS II-SENSITIVE BRAIN TISSUE CELL LINE OF CARASSIUS AURATUS GIBELIO AND ESTABLISHING METHOD AND USE THEREOF
    Publication number: 20160017284
    Abstract: The present invention discloses a cyprinid herpesvirus II-sensitive brain tissue cell line of Carassius auratus gibelio and establishing method and use thereof. The cell line is deposited in China Center for Type Culture Collection under an accession number of CCTCC No: C2013179. The brain tissue cell line of Carassius auratus gibelio is in good growth state and sensitive to CyHV-2 that is presently hardly cultured with ordinary fish cell lines. After six passages of CyHV-2 in GiCB cells, viral nucleic acid can still be detected and a cytopathic effect is stable. When ultrathin microscopic sections are prepared from cells having the cytopathic effect, considerable mature CyHV-2 virions and their replication process can be observed in GiCB cells. The construction method of the brain tissue cell line of Carassius auratus gibelio of the present invention has high repeatability, scientific and reasonable conditions.
    Type: Application
    Filed: December 3, 2014
    Publication date: January 21, 2016
    Applicant: Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences
    Inventors: Jie MA, Lingbing ZENG, Nan JIANG, Qian CHEN, Hui ZHAO