Patents by Inventor Lingchen FU

Lingchen FU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TUMOR-DELIVERED MULTI-TARGET THERAPEUTICS FOR COLON CANCER
    Publication number: 20230338436
    Abstract: The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating, self-eradicating, and armed with decoy polypeptides that bind endogenous ligand and block activation of signal transduction cascades associated with cancer cell proliferation and tumor growth. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer.
    Type: Application
    Filed: December 21, 2022
    Publication date: October 26, 2023
    Inventors: Wei KONG, Lingchen FU, Yixin SHI
  • Using tumor-navigating to modulate tumor metabolism
    Patent number: 11717542
    Abstract: The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating and to alter tumor metabolism in the tumor microenvironment. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: August 8, 2023
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Wei Kong, Lingchen Fu, Yixin Shi, Bo Ning
  • Tumor-delivered multi-target therapeutics for colon cancer
    Patent number: 11564954
    Abstract: The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating, self-eradicating, and armed with decoy polypeptides that bind endogenous ligand and block activation of signal transduction cascades associated with cancer cell proliferation and tumor growth. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: January 31, 2023
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Wei Kong, Lingchen Fu, Yixin Shi
  • TUMOR-DELIVERED MULTI-TARGET THERAPEUTICS FOR COLON CANCER
    Publication number: 20220143105
    Abstract: The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating, self-eradicating, and armed with decoy polypeptides that bind endogenous ligand and block activation of signal transduction cascades associated with cancer cell proliferation and tumor growth. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer.
    Type: Application
    Filed: February 20, 2020
    Publication date: May 12, 2022
    Inventors: Wei KONG, Lingchen FU, Yixin SHI
  • USING TUMOR-NAVIGATING SALMONELLA TO MODULATE TUMOR METABOLISM
    Publication number: 20210386795
    Abstract: The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating and to alter tumor metabolism in the tumor microenvironment. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer.
    Type: Application
    Filed: February 20, 2020
    Publication date: December 16, 2021
    Inventors: Wei KONG, Lingchen FU, Yixin SHI, Bo NING