Patents by Inventor Linghe XIA

Linghe XIA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Asparaginic acid kinase III mutant and host cells and use thereof
    Patent number: 9896734
    Abstract: Provided in the present invention is an asparaginic acid kinase, and the 340th amino acid residue in the position of the amino acid sequence of the asparaginic acid kinase corresponding to the amino acid sequence shown in SEQ ID NO: 2 is a non-aspartic acid. The asparaginic acid of the present invention can efficiently relieve the feedback inhibition of L-lysine, and can be effectively used for the production of L-lysine. Also provided in the present invention are host cells comprising genes coding the asparaginic acid kinase and a method for producing L-lysine using the host cells or the asparaginic acid kinase. The asparaginic acid kinase of the present invention or the host cells comprising the asparaginic acid kinase of the present invention is also used to produce L-threonine, L-methionine, L-isoleucine or L-valine. Also provided in the present invention is a method of producing L-aspartyl-4-yl phosphoric acid using the asparaginic acid kinase or the host cells.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: February 20, 2018
    Assignees: Cofco Biochemical (Anhui) Co., Ltd., Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences
    Inventors: Guojun Yue, Jibin Sun, Ping Zheng, Jiao Liu, Qinggang Li, Linghe Xia, Yongsheng Zhou, Hu Luo, Yong Zhou, Yun Man, Zongmei Lu, Yanhe Ma
  • ASPARAGINIC ACID KINASE III MUTANT AND HOST CELLS AND USE THEREOF
    Publication number: 20150337346
    Abstract: Provided in the present invention is an asparaginic acid kinase, and the 340th amino acid residue in the position of the amino acid sequence of the asparaginic acid kinase corresponding to the amino acid sequence shown in SEQ ID NO: 2 is a non-aspartic acid. The asparaginic acid of the present invention can efficiently relieve the feedback inhibition of L-lysine, and can be effectively used for the production of L-lysine. Also provided in the present invention are host cells comprising genes coding the asparaginic acid kinase and a method for producing L-lysine using the host cells or the asparaginic acid kinase. The asparaginic acid kinase of the present invention or the host cells comprising the asparaginic acid kinase of the present invention is also used to produce L-threonine, L-methionine, L-isoleucine or L-valine. Also provided in the present invention is a method of producing L-aspartyl-4-yl phosphoric acid using the asparaginic acid kinase or the host cells.
    Type: Application
    Filed: May 16, 2013
    Publication date: November 26, 2015
    Applicant: COFCO BIOCHEMICAL (ANHUI) CO. LTD
    Inventors: Guojun YUE, Jibin SUN, Ping ZHENG, Jiao LIU, Qinggang LI, Linghe XIA, Yongsheng ZHOU, Hu LUO, Yong ZHOU, Yun MAN, Zongmei LU, Yanhe MA