Patents by Inventor Lingqiao ZHU

Lingqiao ZHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-HUMAN MASP-2 ANTIBODY, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20240043563
    Abstract: Disclosed are an antibody that can bind to human MASP-2, a preparation method therefor and an application thereof. The anti-human MASP-2 antibody of the present invention can specifically bind to human MASP-2, has good biological activity of inhibiting the cleavage of C4 and the generation of C3b, and can be applied in the treatment of MASP-2 related diseases, such as IgA nephropathy.
    Type: Application
    Filed: October 13, 2023
    Publication date: February 8, 2024
    Inventors: Yipan WU, Wei DANG, Chenghai ZHANG, Lingqiao ZHU, Jinlin GUO, Yujing YUAN, Qiuling ZOU, Yang WANG, Shun HU
  • Anti-PD-1 monoclonal antibody, and preparation method therefor and application thereof
    Patent number: 11254746
    Abstract: An anti-human PD-1 monoclonal antibody, and a preparation method therefor and an application thereof. The anti-human PD-1 monoclonal antibody has good bioactivity, can effectively bind with an extracellular region of a human PD-1 protein receptor, and can effectively seal PD-1 protein at protein level and cellular level and block the binding of the PD-1 protein with a ligand PD-L1, thereby effectively enhancing immunity. The monoclonal antibody can be applied independently or jointly with other antitumor drugs to tumor immunotherapy and the diagnosis and screening of patients with PD-L1 positive tumors; and the monoclonal antibody has a promising prospect in the preparation of drugs for treating tumors, resisting autoimmune diseases and the like.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: February 22, 2022
    Assignee: SUNSHINE GUOJIAN PHARMACEUTICAL (SHANGHAI) CO., LT
    Inventors: Jie Zhao, Honghai Gao, Jinlin Guo, Wei Dang, Lingqiao Zhu, Chenghai Zhang, Le Zhao, Jianhe Chen, Haomin Huang, Zhenping Zhu
  • ANTI-PD-1 MONOCLONAL ANTIBODY, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20200377597
    Abstract: An anti-human PD-1 monoclonal antibody, and a preparation method therefor and an application thereof. The anti-human PD-1 monoclonal antibody has good bioactivity, can effectively bind with an extracellular region of a human PD-1 protein receptor, and can effectively seal PD-1 protein at protein level and cellular level and block the binding of the PD-1 protein with a ligand PD-L1, thereby effectively enhancing immunity. The monoclonal antibody can be applied independently or jointly with other antitumor drugs to tumor immunotherapy and the diagnosis and screening of patients with PD-L1 positive tumors; and the monoclonal antibody has a promising prospect in the preparation of drugs for treating tumors, resisting autoimmune diseases and the like.
    Type: Application
    Filed: January 22, 2018
    Publication date: December 3, 2020
    Inventors: Jie Zhao, Honghai Gao, Jinlin Guo, Wei Dang, Lingqiao Zhu, Chenghai Zhang, Le Zhao, Jianhe Chen, Haomin Huang, Zhenping Zhu
  • Anti-human interleukin-17A monoclonal antibody
    Patent number: 10738112
    Abstract: An anti-human IL-17A monoclonal antibody, the preparation method, and the use thereof are provided. The anti-human IL-17A monoclonal antibody can specifically bind to human IL-17A and has a good effect for inhibiting the secretion of inflammatory cytokines, such as IL-6 and the like by means of various cell lines induced by IL-17A, and can be used for preparing drugs for treating diseases involving immune-medicated inflammatory responses.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: August 11, 2020
    Assignee: SUNSHINE GUOJIAN PHARMACEUTICAL (SHANGHAI) CO., LTD.
    Inventors: Chenghai Zhang, Lingqiao Zhu, Jinlin Guo, Jie Zhao, Honghai Gao, Lin Ma, Wei Dang, Yan Yang
  • ANTI-HUMAN INTERLEUKIN-17A MONOCLONAL ANTIBODY, AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20190161544
    Abstract: An anti-human IL-17A monoclonal antibody, the preparation method, and the use thereof are provided. The anti-human IL-17A monoclonal antibody can specifically bind to human IL-17A and has a good effect for inhibiting the secretion of inflammatory cytokines, such as IL-6 and the like by means of various cell lines induced by IL-17A, and can be used for preparing drugs for treating diseases involving immune-medicated inflammatory responses.
    Type: Application
    Filed: June 9, 2017
    Publication date: May 30, 2019
    Inventors: Chenghai ZHANG, Lingqiao ZHU, Jinlin GUO, Jie ZHAO, Honghai GAO, Lin MA, Wei DANG, Yan YANG