Patents by Inventor Lingwen Cui

Lingwen Cui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
    Patent number: 11918650
    Abstract: The present invention provides an improved pharmaceutical composition for storage and administration comprising (a) a bispecific antibody construct comprising a first domain binding to a target cell surface antigen and a second domain binding to a second antigen, wherein the bispecific antibody construct is present at a concentration in the range from about 0.5 ?g/ml to 20 mg/ml, (b) a preservative at a concentration effective to inhibit the growth of microbes, and (c) a diluent wherein bispecific antibody construct is stable and recoverable.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: March 5, 2024
    Assignee: AMGEN INC.
    Inventors: Jeff Abel, Lingwen Cui, Devrishi Goswami, Joon Huh, Bharadwaj Jagannathan, Sekhar Kanapuram, Arnold McAuley, Michael Schneider, Ananthakrishnan G. Sethuraman, Michael Treuheit, Jun Zhang
  • PHARMACEUTICAL COMPOSITION COMPRISING BISPECIFIC ANTIBODY CONSTRUCTS FOR IMPROVED STORAGE AND ADMINISTRATION
    Publication number: 20190151448
    Abstract: The present invention provides an improved pharmaceutical composition for storage and administration comprising (a) a bispecific antibody construct comprising a first domain binding to a target cell surface antigen and a second domain binding to a second antigen, wherein the bispecific antibody construct is present at a concentration in the range from about 0.5 ?g/ml to 20 mg/ml, (b) a preservative at a concentration effective to inhibit the growth of microbes, and (c) a diluent wherein bispecific antibody construct is stable and recoverable.
    Type: Application
    Filed: May 7, 2018
    Publication date: May 23, 2019
    Inventors: Jeff Abel, Lingwen Cui, Devrishi Goswami, Joon Huh, Bharadwaj Jagannathan, Sekhar Kanapuram, Arnold McAuley, Michael Schneider, Ananthakrishnan G. Sethuraman, Michael Treuheit, Jun Zhang