Patents by Inventor Lining Cai

Lining Cai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of protein kinases
    Patent number: 10106538
    Abstract: Protein kinases are regulators of cellular signaling and their functional dysregulation is common in carcinogenesis and many other disease states or disorders. The present invention relates to novel chemical entities that have biological activity to modulate mammalian protein kinase enzymes. In particular, compounds of the invention display potent inhibition of breast tumor related kinase (BRK).
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: October 23, 2018
    Assignee: Princeton Drug Discovery Inc
    Inventors: Kan He, Lining Cai
  • NOVEL INHIBITORS OF PROTEIN KINASES
    Publication number: 20180118745
    Abstract: Protein kinases are regulators of cellular signaling and their functional dysregulation is common in carcinogenesis and many other disease states or disorders. The present invention relates to novel chemical entities that have biological activity to modulate mammalian protein kinase enzymes. In particular, compounds of the invention display potent inhibition of breast tumor related kinase (BRK).
    Type: Application
    Filed: December 29, 2017
    Publication date: May 3, 2018
    Applicant: PRINCETON DRUG DISCOVERY INC
    Inventors: Kan He, Lining Cai
  • Inhibitors of protein kinases
    Patent number: 9890163
    Abstract: Protein kinases are regulators of cellular signaling and their functional dysregulation is common in carcinogenesis and many other disease states or disorders. The present invention relates to novel chemical entities that have biological activity to modulate mammalian protein kinase enzymes. In particular, compounds of the invention display potent inhibition of breast tumor related kinase (BRK).
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: February 13, 2018
    Assignee: Princeton Drug Discovery Inc
    Inventors: Kan He, Lining Cai
  • NOVEL INHIBITORS OF PROTEIN KINASES
    Publication number: 20170240545
    Abstract: Protein kinases are regulators of cellular signaling and their functional dysregulation is common in carcinogenesis and many other disease states or disorders. The present invention relates to novel chemical entities that have biological activity to modulate mammalian protein kinase enzymes. In particular, compounds of the invention display potent inhibition of breast tumor related kinase (BRK).
    Type: Application
    Filed: October 11, 2016
    Publication date: August 24, 2017
    Applicant: Princeton Drug Discovery, LLC
    Inventors: Kan He, Lining Cai