Patents by Inventor Lining Guo

Lining Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040191852
    Abstract: The present inventors have discovered that NADPH:protochlorophyllide oxidoreductase (POR) is essential for plant growth. Specifically, the inhibition of POR gene expression in plant seedlings results in reduced growth and chlorosis. Thus, POR is useful as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of herbicides by measuring the activity of a POR in the presence and absence of a compound, wherein an alteration of POR activity in the presence of the compound indicates the compound as a candidate for a herbicide.
    Type: Application
    Filed: March 27, 2003
    Publication date: September 30, 2004
    Inventors: Keith Davis, Adel Zayed, Robert Ascenzi, Douglas Boyes, Rao Mulpuri, Neil Hoffman, Susanne Kjemtrup, Carol Hamilton, Jeffrey Woessner, Jorn Gorlach, Lining Guo, Veeresh Sevala
  • Publication number: 20040191851
    Abstract: The present inventors have discovered that Lipid Transfer Protein (LTP) is essential for plant growth. Specifically, the inhibition of LTP gene expression in plant seedlings results in reduced growth and chlorosis. Thus, LTP is useful as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of herbicides by measuring the activity of an LTP in the presence and absence of a compound, wherein an alteration of LTP activity in the presence of the compound indicates the compound as a candidate for a herbicide.
    Type: Application
    Filed: March 27, 2003
    Publication date: September 30, 2004
    Inventors: Angelika Reichert, Lining Guo, Keith Davis, Adel Zayed, Robert Ascenzi, Douglas Boyes, Rao Mulpuri, Neil Hoffman, Susanne Kjemtrup, Carol Hamilton, Jeffrey Woessner, Jorn Gorlach
  • Patent number: 6770452
    Abstract: The present inventors have discovered that serine acetyltransferase (SAT) is essential for plant growth. Specifically, the inhibition of SAT gene expression in plant seedlings results in reduced growth and altered pigmentation. Thus, SAT is useful as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of herbicides by measuring the activity of an SAT in the presence and absence of a compound, wherein an alteration of SAT activity in the presence of the compound indicates the compound as a candidate for a herbicide.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: August 3, 2004
    Assignee: Paradigm Genetics, Inc.
    Inventors: John W Rice, Lining Guo, Keith Davis, Adel Zayed, Robert Ascenzi, Joseph Cameron Mitchell, Daniel N Riggsbee, Douglas Boyes, Rao Mulpuri, Neil Hoffman, Susanne Kjemtrup, Carol Hamilton, Jeffrey Woessner, Jorn Gorlach
  • Patent number: 6717035
    Abstract: Novel polynucleotide sequences that encode insect toxins TcdA and TcbA have base compositions that differ substantially from the native genes, making them more similar to plant genes. The new sequences are suitable for use for high expression in both monocots and dicots. Transgenic plants with a genome comprising the nucleic acid of SEQ ID NO:4 are insect resistant.
    Type: Grant
    Filed: May 12, 2003
    Date of Patent: April 6, 2004
    Assignee: Dow AgroSciences LLC
    Inventors: James K. Petell, Donald J. Merlo, Rod A. Herman, Jean L. Roberts, Lining Guo, Barry W. Schafer, Kitisri Sukhapinda, Ann Owens Merlo
  • Publication number: 20030207806
    Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
    Type: Application
    Filed: October 2, 2002
    Publication date: November 6, 2003
    Inventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. Ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L. Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
  • Publication number: 20030182685
    Abstract: Novel polynucleotide sequences that encode insect toxins TcdA and TcbA have base compositions that differ substantially from the native genes, making them more similar to plant genes. The new sequences are suitable for use for high expression in both monocots and dicots. Transgenic plants with a genome comprising a nucleic acid of SEQ ID NO: 3 or SEQ ID NO:4 are insect resistant.
    Type: Application
    Filed: May 12, 2003
    Publication date: September 25, 2003
    Inventors: James K. Petell, Donald J. Merlo, Rod A. Herman, Jean L. Roberts, Lining Guo, Barry W. Schafer, Kitisri Sukhapinda, Ann Owens Merlo
  • Patent number: 6590142
    Abstract: Novel polynucleotide sequences that encode insect toxins TcdA and TcbA have base compositions that differ substantially from the native genes, making them more similar to plant genes. The new sequences are suitable for use for high expression in both monocots and dicots. Transgenic plants with a genome comprising a nucleic acid of SEQ ID NO: 3 or SEQ ID NO:4 are insect resistant.
    Type: Grant
    Filed: August 11, 2000
    Date of Patent: July 8, 2003
    Assignee: Dow AgroSciences LLC
    Inventors: James K. Petell, Donald J. Merlo, Rod A. Herman, Jean L. Roberts, Lining Guo, Barry W. Schafer, Kitisri Sukhapinda, Ann Owens Merlo
  • Patent number: 6528484
    Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: March 4, 2003
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L. Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
  • Publication number: 20030014775
    Abstract: An enzymatic nucleic acid molecule with RNA cleaving activity, wherein said nucleic acid molecule modulates the expression of an gene in a plant. A transgenic plant comprising nucleic acids encoding for an enzymatic nucleic acid molecule with RNA cleaving activity, wherein said nucleic acid molecule modulates the expression of a gene in said plant.
    Type: Application
    Filed: September 21, 2001
    Publication date: January 16, 2003
    Applicant: Ribozyme Pharmaceuticals, Inc.
    Inventors: Michael G. Zwick, Brent V. Edington, James A. McSwiggen, Patricia Ann Owens Merlo, Lining Guo, Thomas A. Skokut, Scott A. Young, Otto Folkerts, Donald J. Merlo
  • Patent number: 6350934
    Abstract: The present invention relates to nucleic acid molecules encoding delta 9 desaturase gene, and expression vectors, plant cells, and transgenic plants expressing delta 9 desaturase nucleic acid. The nucleic acid molecules of the present invention can be used, for example, to decrease delta 9 desaturase activity in plant cells, resulting in decreased unsaturated fatty acid production.
    Type: Grant
    Filed: July 12, 1996
    Date of Patent: February 26, 2002
    Assignees: Ribozyme Pharmaceuticals, Inc., DowElanco
    Inventors: Michael G. Zwick, Brent E. Edington, James A. McSwiggen, Patricia Ann Owens Merlo, Lining Guo, Thomas A. Skokut, Scott A. Young, Otto Folkerts, Donald J. Merlo
  • Patent number: 6331664
    Abstract: Genes encoding maize oleoyl-ACP and palmitoyl-ACP thioesterase enzymes have been isolated from maize. These genes, when expressed in a plant, can be used to create transgenic plants having altered palmitic acid oil profiles.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: December 18, 2001
    Assignee: Dow AgroSciences LLC
    Inventors: Beth Rubin-Wilson, Lining Guo, Tom Skokut, Scott Young, Otto Folkerts, Katherine Armstrong, Neil M. Cowen