Patents by Inventor Linkun An

Linkun An has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Furoquinolinediones as inhibitors of TDP2
    Patent number: 11999747
    Abstract: Compounds of Formula I and the pharmaceutically acceptable salts thereof are disclosed The variables X1, X2, and R1-4 are disclosed herein. The compounds are useful for treating cancer and related proliferative diseases. Pharmaceutical compositions containing compounds of Formula I and methods of treatment comprising administering compounds of Formula I are also disclosed.
    Type: Grant
    Filed: January 11, 2021
    Date of Patent: June 4, 2024
    Assignee: The United States of America, as Represented by the Secretary, Dept of Health & Human Services
    Inventors: Linkun An, Christophe Marchand, Yves Pommier
  • FUROQUINOLINEDIONES AS INHIBITORS OF TDP2
    Publication number: 20210139492
    Abstract: Compounds of Formula I and the pharmaceutically acceptable salts thereof are disclosed The variables X1, X2, and R1-4 are disclosed herein. The compounds are useful for treating cancer and related proliferative diseases. Pharmaceutical compositions containing compounds of Formula I and methods of treatment comprising administering compounds of Formula I are also disclosed.
    Type: Application
    Filed: January 11, 2021
    Publication date: May 13, 2021
    Inventors: Linkun An, Christophe Marchand, Yves Pommier
  • Furoquinolinediones as inhibitors of TDP2
    Patent number: 10906914
    Abstract: Compounds of Formula I and the pharmaceutically acceptable salts thereof are disclosed Formula I. The variables X1, X2, and R1-4 are disclosed herein. The compounds are useful for treating cancer and related proliferative diseases. Pharmaceutical compositions containing compounds of Formula I and methods of treatment comprising administering compounds of Formula I are also disclosed.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: February 2, 2021
    Assignees: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, SUN YAT-SEN UNIVERSITY
    Inventors: Linkun An, Christophe Marchand, Yves Pommier
  • FUROQUINOLINEDIONES AS INHIBITORS OF TDP2
    Publication number: 20180009822
    Abstract: Compounds of Formula I and the pharmaceutically acceptable salts thereof are disclosed Formula I. The variables X1, X2, and R1-4 are disclosed herein. The compounds are useful for treating cancer and related proliferative diseases. Pharmaceutical compositions containing compounds of Formula I and methods of treatment comprising administering compounds of Formula I are also disclosed.
    Type: Application
    Filed: January 8, 2016
    Publication date: January 11, 2018
    Inventors: Linkun An, Christophe Marchand, Yves Pommier