Patents by Inventor Linli He

Linli He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Asymmetric synthesis of funapide
    Patent number: 10100060
    Abstract: This invention is directed to asymmetric synthesis of funapide, which is useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: October 16, 2018
    Assignee: Xenon Pharmaceuticals Inc.
    Inventors: Ronen Ben-David, Jian Chen, Michael A. Christie, Mina Gadelrab Dimitri, Graciela Noemi Gershon, Linli He, Nelson G. Landmesser, Daniel V. Levy, Orel Yosef Mizrahi, Partha S. Mudipalli, Harlan F. Reese, Joseph A. Sclafani, Yi Wang
  • ASYMMETRIC SYNTHESIS OF FUNAPIDE
    Publication number: 20180002341
    Abstract: This invention is directed to asymmetric synthesis of funapide, which is useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
    Type: Application
    Filed: June 16, 2017
    Publication date: January 4, 2018
    Inventors: Ronen Ben-David, Jian Chen, Michael A. Christie, Mina Gadelrab Dimitri, Graciela Noemi Gershon, Linli He, Nelson G. Landmesser, Daniel V. Levy, Orel Yosef Mizrahi, Partha S. Mudipalli, Harlan F. Reese, Joseph A. Sclafani, Yi Wang
  • Forms of a multicyclic compound
    Patent number: 8633314
    Abstract: The present invention provides alternative forms of Compound I, processes to reproducibly make them and methods of treating patients using them.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: January 21, 2014
    Assignee: Cephalon, Inc.
    Inventors: Stephen Bierlmaier, Michael Christie, R. Scott Field, R. Curtis Haltiwanger, Linli He, Martin J. Jacobs, Michael Kress, Robert E. McKean, Dale R. Mowrey, Joseph Petraitis, Mehran Yazdanian, Veronique Courvoisier
  • Novel forms of a multicyclic compound
    Publication number: 20120214998
    Abstract: The present invention provides alternative forms of Compound I, processes to reproducibly make them and methods of treating patients using them.
    Type: Application
    Filed: February 24, 2012
    Publication date: August 23, 2012
    Applicant: Cephalon, Inc.
    Inventors: Stephen Bierlmaier, Michael Christie, Laurent Courvoisier, Veronique Courvoisier, R. Scott Field, R. Curtis Haltiwanger, Linli He, Martin J. Jacobs, Michael Kress, Robert E. McKean, Dale R. Mowrey, Joseph Petraitis, Mehran Yazdanian
  • METHOD OF PREPARING HUPERZINE A AND DERIVATIVES THEREOF
    Publication number: 20090247754
    Abstract: The present invention is related to the synthesis of huperzine A. The synthesis includes a variety of process steps that increase productivity, reduce safety concerns, and allow for increasing production of compounds of desired optical isomer. The inventive methods may encompass a single improved reaction step that may be incorporated into a known reaction process for synthesizing huperzine A or a derivative thereof to improve the overall reaction. The inventive methods also encompass complete synthesis methods for preparing huperzine A or a derivative thereof.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 1, 2009
    Inventors: Gail Underiner, Frank Gibson, Linli He, Harihara Subramanian Meera, Jesudoss Mercy Gnanadeepam, Ramanathan Saiganesh, Stephen R. Tudhope, Manouchehr Azadi-Ardakani