Patents by Inventor Linlin Yin

Linlin Yin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Flavanone derivatives, and preparation method and use thereof
    Patent number: 10513512
    Abstract: The invention relates to flavanone derivatives, and preparation method and use thereof, particularly relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same, a preparation method thereof, and use thereof for preventing or treating a mental disorder or a nervous system disease. The compound of the invention exerts significant activity of inhibiting microglial activation and neuroinflammation, can antagonize dopamine D2 receptor, improve the ethological change in multiple animal models for mental disorders, effectively inhibit neuroinflammation and demyelination, and can be used to prevent or treat a mental disorder and a nervous system disease.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: December 24, 2019
    Assignee: Xuanwu Hospital of Capital Medical University
    Inventors: Lin Li, Hongshun Gu, Lan Zhang, Xi Chen, Linlin Yin, Ruyi Zhang, Cuicui Yang
  • FLAVANONE DERIVATIVES, AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20190031644
    Abstract: The invention relates to flavanone derivatives, and preparation method and use thereof, particularly relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same, a preparation method thereof, and use thereof for preventing or treating a mental disorder or a nervous system disease. The compound of the invention exerts significant activity of inhibiting microglial activation and neuroinflammation, can antagonize dopamine D2 receptor, improve the ethological change in multiple animal models for mental disorders, effectively inhibit neuroinflammation and demyelination, and can be used to prevent or treat a mental disorder and a nervous system disease.
    Type: Application
    Filed: January 11, 2017
    Publication date: January 31, 2019
    Applicant: Xuanwu Hospital of Capital Medical University
    Inventors: Lin LI, Hongshun GU, Lan ZHANG, Xi CHEN, Linlin YIN, Ruyi ZHANG, Cuicui YANG
  • Composition containing iridoids and uses thereof
    Patent number: 9233116
    Abstract: Composition containing iridoids such as morroniside and loganin, the use thereof in preparing medicaments for preventing and treating neurologic demyelinating diseases, and the method thereof in treating diseases related to neurologic demyelinating lesions are disclosed by the present application.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: January 12, 2016
    Assignee: XUANWU HOSPITAL OF CAPITAL MEDICAL UNIVERSITY
    Inventors: Lin Li, Linlin Yin, Lan Zhang, Wen Wang, Ruyi Zhang
  • Use of icariin and epimedium flavonoids containing icariin to treat diseases associated with myelin sheath lesion
    Patent number: 9050353
    Abstract: New use of icariin and Epimedium flavaoids containing icariin is provided by the present invention.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: June 9, 2015
    Assignee: Xuanwu Hospital of Capital Medical University
    Inventors: Lin Li, Linlin Yin, Lili Lin, Lan Zhang, Wen Wang, Ruyi Zhang
  • NEW USE OF ICARIIN AND EPIMEDIUM FLAVONOIDS CONTAINING ICARIIN
    Publication number: 20130157966
    Abstract: New use of icariin and Epimedium flavaoids containing icariin is provided by the present invention.
    Type: Application
    Filed: June 7, 2011
    Publication date: June 20, 2013
    Applicant: Xuanwu Hospital of Capital Medical University
    Inventors: Lin Li, Linlin Yin, Lili Lin, Lan Zhang, Wen Wang, Ruyi Zhang
  • COMPOSITION CONTAINING IRIDOIDS AND USES THEREOF
    Publication number: 20130116205
    Abstract: Composition containing iridoids such as morroniside and loganin, the use thereof in preparing medicaments for preventing and treating neurologic demyelinating diseases, and the method thereof in treating diseases related to neurologic demyelinating lesions are disclosed by the present application.
    Type: Application
    Filed: December 15, 2010
    Publication date: May 9, 2013
    Applicant: XUANWU HOSPITAL OF CAPITAL MEDICAL UNIVERSITY
    Inventors: Lin Li, Linlin Yin, Lan Zhang, Wen Wang, Ruyi Zhang