Patents by Inventor Lino Colombo

Lino Colombo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the preparation of rufinamide
    Patent number: 8198459
    Abstract: The invention provides a novel process for the regioselective preparation of a compound of formula (I)
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: June 12, 2012
    Assignee: Dipharma Francis S.r.l.
    Inventors: Emanuele Attolino, Lino Colombo, Ilaria Mormino, Pietro Allegrini
  • METHOD FOR THE PREPARATION OF RUFINAMIDE
    Publication number: 20100234616
    Abstract: The invention provides a novel process for the regioselective preparation of a compound of formula (I)
    Type: Application
    Filed: March 12, 2010
    Publication date: September 16, 2010
    Applicant: DIPHARMA FRANCIS S.R.L.
    Inventors: Emanuele ATTOLINO, Lino COLOMBO, Ilaria MORMINO, Pietro ALLEGRINI
  • PROCESS FOR THE PREPARATION OF KETO INTERMEDIATES
    Publication number: 20100228034
    Abstract: Process for the preparation of 4-[1-oxo-4-[4-(hydroxyphenylmethyl)-1-piperidinyl]butyl]-?,?-dimethylbenzenacetic acid, which is an intermediate useful in the preparation of fexofenadine, by hydrating asymmetric alkynes.
    Type: Application
    Filed: January 25, 2010
    Publication date: September 9, 2010
    Applicant: DIPHARMA FRANCIS S.r.I.
    Inventors: Emanuele ATTOLINO, Lino Colombo, Ada Maria Zurlo, Marco Artico, Pietro Allegrini
  • Process for the preparation of solifenacin
    Publication number: 20090203915
    Abstract: A process for the preparation of (1S,3?R)-quiniclidin-3?-yl-1-phenyl-3,4-dihydro-1H-isoquinolin-2-carboxylate, namely solifenacin, comprising the reaction of a compound of formula (IV) with a compound of formula (V), as herein defined, and the subsequent reaction with 3-quinuclidinol.
    Type: Application
    Filed: January 30, 2009
    Publication date: August 13, 2009
    Applicant: Dipharma Francis S.r.l.
    Inventors: Pietro Allegrini, Lino Colombo, Marco Brusasca, Chiara Vladiskovic, Gabriele Razzetti, Emanuele Attolino
  • Process for the Preparation of Oxazolidinone Derivatives
    Publication number: 20090156806
    Abstract: A process for the preparation of oxazolidinone derivatives, in particular [(S)—N-[[3-(3-fluoro-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide] (linezolid), and novel intermediates useful for the synthesis thereof.
    Type: Application
    Filed: December 11, 2008
    Publication date: June 18, 2009
    Applicant: Dipharma Francis S.r.I.
    Inventors: Lino Colombo, Pietro Allegrini, Marco Brusasca, Giuseppe D'Arienzo, Gabriele Razzetti
  • PROCESS FOR THE PREPARATION OF IMIQUIMOD AND INTERMEDIATES THEREOF
    Publication number: 20080161573
    Abstract: Novel intermediates useful for the preparation of Imiquimod and a process for the preparation of Imiquimod with the intermediates.
    Type: Application
    Filed: October 16, 2007
    Publication date: July 3, 2008
    Applicant: DIPHARMA S.P.A.
    Inventors: Lino COLOMBO, Enrico Mariotti, Pietro Allegrini, Graziano Castaldi
  • A PROCESS FOR THE PREPARATION OF PHENYLTETRAZOLE COMPOUNDS
    Publication number: 20080076932
    Abstract: A process for the preparation of olmesartan medoxomil, and derivatives thereof, by use of novel phenyltetrazole intermediates.
    Type: Application
    Filed: September 26, 2007
    Publication date: March 27, 2008
    Applicant: DIPHARMA FRANCIS S.R.L.
    Inventors: Gabriele RAZZETTI, Lino COLOMBO, Paola ROTA, Pietro ALLEGRINI
  • PROCESS FOR THE PREPARATION OF NITRILE COMPOUNDS
    Publication number: 20080039640
    Abstract: A process for the preparation of a compound of formula (I) or a salt thereof wherein R is an amino, nitro or —NHCOR1 group, wherein R1 is C1-C6 alkyl or phenyl optionally substituted by a —O—(CH2)n-phenyl group, wherein n is an integer of 1 to 6; comprising reacting a compound of formula (II) or a salt thereof, both as the individual isomer and as an isomeric mixture, wherein R is as defined above; with a dehydrating agent, if necessary in the presence of an organic solvent, and optionally in the presence of a basic agent; and, if desired, converting a compound of formula (I) to another compound of formula (I) or a salt thereof.
    Type: Application
    Filed: August 8, 2007
    Publication date: February 14, 2008
    Applicant: DIPHARMA FRANCIS S.R.L.
    Inventors: Lino COLOMBO, Pietro ALLEGRINI, Alessandra AMOROSI, Gabriele RAZZETTI, Roberto ROSSI
  • Process for the preparation of Imiquimod and intermediates thereof
    Patent number: 7301027
    Abstract: Novel intermediates useful for the preparation of Imiquimod and a process for the preparation of Imiquimod with the intermediates.
    Type: Grant
    Filed: November 3, 2004
    Date of Patent: November 27, 2007
    Assignee: Dipharma S.p.A.
    Inventors: Lino Colombo, Enrico Mariotti, Pietro Allegrini, Graziano Castaldi
  • Process for the preparation of tolterodine and intermediates thereof
    Patent number: 7119212
    Abstract: A process for the preparation of 6-methyl-4-(R)-phenyl-chroman-2-one and 6-methyl-4-(S)-phenyl-chroman-2-one, intermediates for the synthesis of tolterodine and its (S) enantiomer, by reaction of 6-methyl-coumarin with phenylboronic acids, esters and derivatives thereof, in the presence of chiral catalysts.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: October 10, 2006
    Assignee: Dipharma S.p.A.
    Inventors: Lino Colombo, Roberto Rossi, Pietro Allegrini, Graziano Castaldi
  • Process for the preparation of tolterodine and intermediates thereof
    Publication number: 20050222437
    Abstract: A process for the preparation of 6-methyl-4-(R)-phenyl-chroman-2-one and 6-methyl-4-(S)-phenyl-chroman-2-one, intermediates for the synthesis of tolterodine and its (S) enantiomer, by reaction of 6-methyl-coumarin with phenylboronic acids, esters and derivatives thereof, in the presence of chiral catalysts.
    Type: Application
    Filed: March 29, 2005
    Publication date: October 6, 2005
    Applicant: DIPHARMA S.P.A.
    Inventors: Lino Colombo, Roberto Rossi, Pietro Allegrini, Graziano Castaldi
  • Process for the preparation of Imiquimod and intermediates thereof
    Publication number: 20050165236
    Abstract: Novel intermediates useful for the preparation of Imiquimod and a process for the preparation of Imiquimod by means of said intermediates.
    Type: Application
    Filed: November 3, 2004
    Publication date: July 28, 2005
    Inventors: Lino Colombo, Enrico Mariotti, Pietro Allegrini, Graziano Castaldi