Patents by Inventor Linong Zhang

Linong Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN METAPNEUMOVIRUS VACCINES
    Publication number: 20230310571
    Abstract: The present disclosure provides antigenic prefusion hMPV F polypeptides, nucleic acid sequences (e.g., RNA sequences, e.g., mRNA sequences) encoding prefusion hMPV F polypeptides, compositions comprising antigenic prefusion hMPV F polypeptides, compositions comprising nucleic acid sequences encoding prefusion hMPV F polypeptides, and hMPV vaccines.
    Type: Application
    Filed: November 29, 2022
    Publication date: October 5, 2023
    Inventors: Yvonne Chan, Sukanya Sasmal, Antonia Stuebler, Michael Kishko, Sophia Mundle, Linong Zhang, Josh DiNapoli, Judith Alamares-Sapuay, Natalie Anosova, Sudha Chivukula, Hillary Danz, Tod Strugnell, Rachel Groppo
  • RESPIRATORY SYNCTIAL VIRUS RNA VACCINE
    Publication number: 20230302112
    Abstract: The present disclosure provides a respiratory syncytial virus (RSV) vaccine comprising a messenger RNA (mRNA) comprising an open reading frame (ORF) encoding an RSV F protein antigen, and methods of eliciting an immune response by administering said vaccine.
    Type: Application
    Filed: November 4, 2022
    Publication date: September 28, 2023
    Inventors: Danilo Casimiro, Hardip Rajeshbhai Gopani, Joshua DiNapoli, Linong Zhang, Mark Parrington, Rebecca L. Goldman, Sudha Chivukula, William Scott Gallichan
  • Replication-defective flavivirus vaccines and vaccine vectors
    Patent number: 9217158
    Abstract: This invention provides replication-defective flavivirus vaccines and vaccine vectors, and corresponding compositions and methods.
    Type: Grant
    Filed: October 2, 2012
    Date of Patent: December 22, 2015
    Assignee: Sanofi Pasteur Biologics, LLC
    Inventors: Konstantin V. Pugachev, Maryann Giel-Moloney, Harold Kleanthous, Mark Parrington, Linong Zhang
  • Modified CEA/B7 vector
    Patent number: 8562970
    Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. In particular, the invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer.
    Type: Grant
    Filed: October 6, 2004
    Date of Patent: October 22, 2013
    Assignee: Sanofi Pasteur Limited
    Inventors: Mark Parrington, Linong Zhang, Benjamin Rovinski, Linda Gritz, Patricia Greenhaigh
  • Modified CEA nucleic acid and expression vectors
    Patent number: 8530442
    Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. The invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer. One such foreign DNA sequence is modified CEA nucleic acid.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: September 10, 2013
    Assignee: Sanofi Pasteur Limited
    Inventors: Mark Parrington, Linong Zhang, Benjamin Rovinski, Linda R. Gritz, Patricia Greenhalgh
  • MODIFIED CEA NUCLEIC ACID AND EXPRESSION VECTORS
    Publication number: 20130101625
    Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. The invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer. One such foreign DNA sequence is modified CEA nucleic acid.
    Type: Application
    Filed: June 25, 2012
    Publication date: April 25, 2013
    Inventors: Mark Parrington, Linong Zhang, Benjamin Rovinski, Linda R. Gritz, Patricia Greenhalgh
  • Modified CEA nucleic acid and expression vectors
    Patent number: 8236776
    Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. The invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer. One such foreign DNA sequence is modified CEA nucleic acid.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: August 7, 2012
    Assignee: Sanofi Pasteur Limited
    Inventors: Mark Parrington, Linong Zhang, Benjamin Rovinski, Linda R. Gritz, Patricia Greenhalgh
  • Replication-Defective Flavivirus Vaccine Vectors Against Respiratory Syncytial Virus
    Publication number: 20120128713
    Abstract: Replication-defective vaccine vectors against respiratory syncytial virus (RSV) are disclosed. Corresponding compositions and methods employing the vaccine vectors are also disclosed.
    Type: Application
    Filed: March 16, 2010
    Publication date: May 24, 2012
    Applicants: Sanofi Pasteur Limited, Sanofi Pasteur Biologics Co.
    Inventors: Konstantin V. Pugachev, Alexander A. Rumyantsev, Maryann Giel-Moloney, Mark Parrington, Linong Zhang
  • MODIFIED CEA NUCLEIC ACID AND EXPRESSION VECTORS
    Publication number: 20100285065
    Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. The invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer. One such foreign DNA sequence is modified CEA nucleic acid.
    Type: Application
    Filed: March 2, 2010
    Publication date: November 11, 2010
    Inventors: Mark Parrington, Linong Zhang, Benjamin Rovinski, Linda R. Gritz, Patricia Greenhalgh
  • Modified CEA nucleic acid and expression vectors
    Patent number: 7786278
    Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. The invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer. One such foreign DNA sequence is modified CEA nucleic acid.
    Type: Grant
    Filed: April 9, 2003
    Date of Patent: August 31, 2010
    Inventors: Mark Parrington, Linong Zhang, Benjamin Rovinski, Linda R. Gritz, Patricia Greenhalgh
  • Modified Cea/B7 Vector
    Publication number: 20080113928
    Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. In particular, the invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer.
    Type: Application
    Filed: October 6, 2004
    Publication date: May 15, 2008
    Inventors: Mark Parrington, Linong Zhang, Benjamin Rovinski, Linda Gritz, Patricia Greenhaigh
  • Modified bovine adenovirus having altered tropism
    Patent number: 6849446
    Abstract: The present invention provides modified bovine adenoviruses comprising a modification in a capsid protein wherein said protein is associated with adenovirus tropism and wherein said modification is associated with altered tropism. The present invention provides adenovirus vectors and host cells comprising such vectors. The present invention also provides methods of making and using such adenoviruses.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: February 1, 2005
    Assignee: University of Saskatchewan
    Inventors: Suresh K. Tikoo, Lorne A. Babiuk, Linong Zhang, Qiaohua Wu
  • Modified bovine adenovirus having altered tropism
    Publication number: 20020034519
    Abstract: The present invention provides modified bovine adenoviruses comprising a modification in a capsid protein wherein said protein is associated with adenovirus tropism and wherein said modification is associated with altered tropism. The present invention provides adenovirus vectors and host cells comprising such vectors. The present invention also provides methods of making and using such adenoviruses.
    Type: Application
    Filed: May 31, 2001
    Publication date: March 21, 2002
    Inventors: Suresh K. Tikoo, Lorne A. Babiuk, Linong Zhang, Qiaohua Wu