Patents by Inventor Linqian Yu

Linqian Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapamycin carbonic ester analogues, pharmaceutical compositions, preparations and uses thereof
    Patent number: 8455510
    Abstract: Rapalogs of formula I, pharmaceutically acceptable salts, pharmaceutical compositions, and preparation methods and uses thereof. The rapalogs have the structure of formula I and can be used as an anti-tumor medicament. Comparing with rapamycin, the rapalogs of the present invention exhibit enhanced water solubility, and improved pharmacological and pharmacokinetic properties by introducing a hydrophilic and polar group such as a hydroxyl.
    Type: Grant
    Filed: September 17, 2009
    Date of Patent: June 4, 2013
    Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Fajun Nan, Jian Ding, Jianping Zuo, Linqian Yu, Linghua Meng, Yangming Zhang, Na Yang, Min Gu
  • Rapamycin Carbonic Ester Analogues, Pharmaceutical Compositions, Preparations and Uses Thereof
    Publication number: 20110166172
    Abstract: Rapalogs of formula I, pharmaceutically acceptable salts, pharmaceutical compositions, and preparation methods and uses thereof. The rapalogs have the structure of formula I and can be used as an anti-tumor medicament. Comparing with rapamycin, the rapalogs of the present invention exhibit enhanced water solubility, and improved pharmacological and pharmacokinetic properties by introducing a hydrophilic and polar group such as a hydroxyl.
    Type: Application
    Filed: September 17, 2009
    Publication date: July 7, 2011
    Applicant: Shanghai institute of Materia Medica, chinese Academy of Sciences
    Inventors: Fajun Nan, Jian Ding, Jianping Zuo, Linqian Yu, Linghua Meng, Yangming Zhang, Na Yang, Min Gu