Patents by Inventor Linqiu HUANG

Linqiu HUANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant-type uricase, PEG modified mutant-type uricase, and application thereof
    Patent number: 11021690
    Abstract: A mutant-type uricase, PEG modified mutant-type uricase, and application thereof. The mutant-type uricase has a cysteine residue introduced by recombination, the cysteine residue is located at an inactive region of the uricase, and one or more PEGs are coupled to the mutant-type uricase. The resulting PEGylated mutant-type uricase has characteristics of a half-life extension, product uniformity, and stable enzyme activity. Therefore, the present invention has a wide future application range.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: June 1, 2021
    Assignee: SHANGHAI INSTITUTE OF BIOLOGICAL PRODUCTS CO., LTD.
    Inventors: Yun Jiang, Linqiu Huang, Jueren Lou
  • MUTANT-TYPE URICASE, PEG MODIFIED MUTANT-TYPE URICASE, AND APPLICATION THEREOF
    Publication number: 20180282707
    Abstract: A mutant-type uricase, PEG modified mutant-type uricase, and application thereof. The mutant-type uricase has a cysteine residue introduced by recombination, the cysteine residue is located at an inactive region of the uricase, and one or more PEGs are coupled to the mutant-type uricase. The resulting PEGylated mutant-type uricase has characteristics of a half-life extension, product uniformity, and stable enzyme activity. Therefore, the present invention has a wide future application range.
    Type: Application
    Filed: August 19, 2016
    Publication date: October 4, 2018
    Inventors: Yun JIANG, Linqiu HUANG, Jueren LOU