Abstract: A detection system and a sample processing instrument for nanoparticles are provided. The detection system includes a light emitting unit and a light collection unit. The light emitting unit is configured to emit a light beam and project the light beam onto a nanoparticle to be detected. The light collection unit is configured to collect light beams from the nanoparticle so as to analyze the nanoparticles according to the collected light beams. The light emitting unit includes multiple light sources and a focusing lens, and the light beams emitted by the multiple light sources are focused through the focusing lens on a same detection position through which the nanoparticle is to pass.

Abstract: A method for background detection of a sample pipeline of a sample processor, a sample processor and a computer-readable medium are provided. The sample pipeline is configured to connect a sample probe for aspirating a sample out of a sample container to a flow cell. The method includes the following steps executed by a control device: supplying sheath liquid to the flow cell via the sample pipeline; and detecting the sheath liquid flowing through the flow cell to obtain background detection data. The method according to the present disclosure performs background detection on sample pipeline of the sample processor by using sheath liquid, omitting preparation of a specialized fluid for background detection, significantly reducing costs and avoiding introduction of impurities to increase the background when the specialized fluid is loaded into the sample processor. Therefore, the detection precision and accuracy of the sample processor can be improved.

Abstract: Provided is a method for operating and cleaning a sample processing instrument comprising steps, performed by a control device, of: directing a first sample comprising first particles through a flow cell in the sample processing instrument; processing the first sample; cleaning the flow cell of the sample processing instrument with a cleaning agent; measuring a carryover amount in the flow cell after the cleaning, wherein the carryover amount comprises a measurement associated with an amount of the first particles remaining in a measurement region of the flow cell; comparing the measured carryover amount against a predetermined target value, wherein the target value corresponds to a value indicative of a cleaning requirement; and determining, based on the comparison, whether the cleaning requirement is met.

Abstract: The present disclosure relates to a fluid system for a sample processor and a sample processor including the fluid system. The fluid system includes a sample line, a processing fluid line, a vacuum line, and an air pump. The sample line communicates a sample container with a sample port of a flow cell unit. The processing fluid line communicates a sheath fluid container with a processing fluid port of the flow cell unit. The vacuum line is in communication with the flow cell unit. The air pump includes a first output port and a second output port. Pressurized gas is generated at the first output port, and the first output port is in communication with the sample container and the sheath fluid container. A vacuum is generated at the second output port, and the second output port is in communication with a vacuum port of the flow cell unit through the vacuum line.

Abstract: The invention relates to a cuvette assembly for a sample processor, a flow cell for a sample processor comprising the cuvette assembly, and a sample processor comprising the cuvette assembly or the flow cell. The cuvette assembly comprises a cuvette body and a reflector. The cuvette body is in the shape of a rectangular parallelepiped and comprises a sample detection channel vertically penetrating the cuvette body. The cuvette body has long sides and short sides in a horizontal section. The reflector has a flat surface attached to a first side surface extending along one of the long sides of the cuvette body and a spherical surface that is opposite to the flat surface and has a truncated lower half. The reflector is positioned so that it is flush with a lower surface of the cuvette body and a center of sphere of the spherical surface falls into the sample detection channel, and the reflector extends along the long side and exceeds the short side.

Abstract: The present disclosure relates to a fluid system for a sample processor and a sample processor including the fluid system. The fluid system includes a sample line, a processing fluid line, a vacuum line, and an air pump. The sample line communicates a sample container with a sample port of a flow cell unit. The processing fluid line communicates a sheath fluid container with a processing fluid port of the flow cell unit. The vacuum line is in communication with the flow cell unit. The air pump includes a first output port and a second output port. Pressurized gas is generated at the first output port, and the first output port is in communication with the sample container and the sheath fluid container. A vacuum is generated at the second output port, and the second output port is in communication with a vacuum port of the flow cell unit through the vacuum line.