Abstract: Provided is a set of viral vectors, comprising: a first viral vector that carries a first nucleic acid molecule encoding an envelope protein, and a second viral vector that carries a second nucleic acid molecule encoding a fusion protein, the fusion protein comprising: a single-chain antibody capable of binding to CD28 or CD3, and a C-terminal domain, comprising a transmembrane region and an intracellular region, of the envelope protein. The C terminal of the single-chain antibody is connected to the N terminal of the C-terminal domain of the envelope protein, and the envelope protein and the fusion protein are in a non-fusion form. Also provided are a method for obtaining a lentivirus and an obtained lentivirus, a method for introducing a lentivirus into an unactivated T lymphocyte, a method for expressing a target gene, a method for obtaining a CAR-T cell and an obtained CAR-T cell, a pharmaceutical composition, and a use thereof.

Abstract: A vehicle lighting system comprising a light source for generating light illumination, a liquid lens optically aligned with the light source to receive the light illumination and generate an output beam, and a controller configured to control electric power supplied to the liquid lens. The controller applies a first voltage to the liquid lens to generate a first output beam having a first beam size and generates a second voltage to the liquid lens to generate a second output beam having a wider second beam size.

Abstract: A vehicle lamp assembly includes a light source that emits light, a side marker lamp having a lens, and a frustum reflector that guides light from the light source to the lens of the side marker lamp. A vehicle lighting method includes emitting light from a light source into a frustum reflector, redirecting the light within the frustum reflector, and illuminating a side marker lamp using the light redirected within the frustum reflector.

Abstract: A lamp includes a light source and a light pipe including a light transmissive medium with an elongated body extending along an axial axis. The light pipe has an input for receiving light from the light source and a plurality of prism optics extending into an outside surface of the elongated body in a direction of the axial axis, wherein the plurality of prism optics each has an angle in the range of about 115° (degrees) to 145° (degrees).

Abstract: A vehicle lighting assembly includes a light housing, a lens, a light source within a cavity provided by the light housing and the lens, and a light blade projecting from the lens outside the cavity. A vehicle lighting method includes emitting light from a light source that is inside a cavity provided by a light housing and a lens, and directing the light through a light blade that is outside the cavity.

Abstract: A vehicle lighting assembly includes a primary lens and a light source on a first side of the primary lens. The light source is configured to emit light through the primary lens. A light blade is on an opposite, second side of the primary lens. A secondary lens covers a portion of the light blade. A vehicle lighting method includes emitting light from a light source, directing the light through a primary lens, directing the light from the primary lens through a light blade, and directing the light from the light blade through a secondary lens.

Abstract: A lamp includes a light source, a central lens optically aligned with the light source to receive a first portion of light emitted by the light source and transmit the first portion of light in a first output beam, a side emitting lens generally disposed between the central lens and the light source and arranged to receive a second portion of the light, and a plurality of light guides each having a light input end and operatively coupled to the side emitting lens to receive the second portion of light emitted from the light source that is directed through the side emitting lens and having a light output end, wherein each of the plurality of light guides has a light refraction structure on a first side for directing the second portion of the light in a second output beam from a second side.

Abstract: A vehicle perimeter lighting assembly includes, among other things, a base having a concave area and a support ledge, a light source supported on the support ledge such that light from the light source is emitted toward the concave area, and a reflector lining the concave area. The reflector is configured to redirect light emitted from the light source toward an area around a vehicle.

Abstract: A vehicle lamp assembly includes an LED disposed on a circuit board, a light collimator operatively coupled to the LED to generate a beam of collimated light, a light pipe operatively coupled to light collimator to transmit the collimated beam of light, and a hybrid optic lens operatively coupled to the light pipe to diverge the collimated beam of light into a beam pattern. The hybrid optic lens includes a plurality of curved lenses for outputting light in a first direction, a first prism lens formed on a lower portion of the curved lenses for directing light downward in a second direction, and a second prism lens provided on a lateral side of curved lenses for directing light sideways in a third direction. An enhanced light illumination with uniform lighting pattern in the trailer hitch target region is achieved for operation of a trailer with the vehicle.

Abstract: A backup light apparatus provides a somewhat uniform distribution of light intensity in an area within the view of a backup camera of a vehicle. The backup light apparatus may satisfy various governmental and manufacturer safety rules. The backup light apparatus has a pillow lens array, a first collimator, a prism lens array, and a second collimator. The first collimator directs light in the direction of its optical axis to the pillow lens array. The second collimator directs light in the direction of its optical axis to the prism lens array. The pillow lens array has an array of pillow lenses facing away from the first collimator. The prism lens array has an array of prism lenses facing away from the second collimator. The prism lenses direct light at varying angles relative to the optical axis of the second collimator.

Abstract: A backup light apparatus provides a somewhat uniform distribution of light intensity in an area within the view of a backup camera of a vehicle. The backup light apparatus may satisfy various governmental and manufacturer safety rules. The backup light apparatus has a pillow lens array, a first collimator, a prism lens array, and a second collimator. The first collimator directs light in the direction of its optical axis to the pillow lens array. The second collimator directs light in the direction of its optical axis to the prism lens array. The pillow lens array has an array of pillow lenses facing away from the first collimator. The prism lens array has an array of prism lenses facing away from the second collimator. The prism lenses direct light at varying angles relative to the optical axis of the second collimator.

Abstract: A vehicle lighting system is provided that includes an invisible light source generating invisible light in a region proximate to a seated passenger in the vehicle, an invisible light sensor configured to receive the invisible light reflected from one or more objects in the region, a reading lamp configured to illuminate visible light to the region proximate to the passenger seated in the vehicle, and a controller detecting a presence of reading material in the region based on the reflected invisible light, and controlling the reading lamp to activate the light source when reading material is detected in the region.

Abstract: A light pipe is provided that includes a light transmissive medium having an input at one end and configured to be operatively coupled to a light source, wherein the light transmissive medium defines a first portion connected to a second portion via a first bend portion of about 90°, and a series of prisms formed in the light transmissive medium, each prism having a V-shaped groove with an incline angle of about 45°, wherein each prism has a depth and a length that increases from the first portion to the second portion, and wherein a separation gap between adjacent prisms decreases from the first portion to the second portion. The light pipe may have third and fourth portions and form a U-shape.

Abstract: A lamp assembly is provided herein. The lamp assembly includes a panel operably coupled with one or more projectors. A light source is disposed within each of the one or more projectors. An optical member is disposed between each of the light sources and the panel. An image interference is disposed between the optical member and an exterior surface of the panel.

Abstract: A vehicle lamp assembly includes a housing that defines an opening. A light source is operably coupled with the housing. The light source is configured to emit light. A lens is coupled to the housing proximate the opening. The lens includes a first side that has an A-surface of the lens. A second side has a B-surface of the lens. A first optic defines an interior surface of the first side of the lens. The A-surface is free of the first optic. A second optic is defined on the second side. The first optic and the second optic are aligned to collimate and disperse the light.

Abstract: A vehicle lamp assembly includes a housing that defines an opening. A light source is operably coupled with the housing. The light source is configured to emit light. A lens is coupled to the housing proximate the opening. The lens includes a first side that has an A-surface of the lens. A second side has a B-surface of the lens. A first optic defines an interior surface of the first side of the lens. The A-surface is free of the first optic. A second optic is defined on the second side. The first optic and the second optic are aligned to collimate and disperse the light.

Abstract: A vehicle perimeter lighting assembly includes, among other things, a base having a concave area and a support ledge, a light source supported on the support ledge such that light from the light source is emitted toward the concave area, and a reflector lining the concave area. The reflector is configured to redirect light emitted from the light source toward an area around a vehicle.

Abstract: A vehicle includes a vehicle body that defines a cargo space. The cargo space includes a cargo floor. A trim member is disposed on the vehicle body within the cargo space. The trim member defines an opening. The housing is disposed within the opening. A light source is disposed on the housing. A first lens is disposed adjacent to the light source. The first lens defines a first optic. A second lens is spaced-apart from the first lens. The second lens defines a second optic. The light source is configured to emit light through the first lens and the second lens into the cargo space.

Abstract: A vehicle includes a vehicle body that defines a cargo space. The cargo space includes a cargo floor. A trim member is disposed on the vehicle body within the cargo space. The trim member defines an opening. The housing is disposed within the opening. A light source is disposed on the housing. A first lens is disposed adjacent to the light source. The first lens defines a first optic. A second lens is spaced-apart from the first lens. The second lens defines a second optic. The light source is configured to emit light through the first lens and the second lens into the cargo space.