Abstract: An optics-free method for single cell profiling, particularly white blood cells such as neutrophils is disclosed. Embodiments relate to multi-parametric biophysical profiling of neutrophils using a microfluidic impedance-deformability cytometry device. The device comprises a first flow channel comprising a particle focusing region, a detection region comprising a first pair of electrodes, a cell deformation zone and a second pair of electrodes. A multi-frequency impedance response of each cell before and after deformation is measured respectively by the first and second pairs of electrodes, such as to quantify membrane opacity, nucleus opacity, cell size and deformability index. A second flow channel bifurcated into two split flow pathways that converge in an intersecting manner with the first flow channel forms a cross-junction in a cell deformation zone, to hydrodynamically deform each cell by perfusing a sheath fluid along the two split flow paths from two opposite sides of the sample flow channel.

Abstract: The invention provides a two-dimensional chalcogenide, which is a crystalline material, and has a chemical formula of (NH4)2[Sn3S7]·(C4H13N3)1.41, cell parameters of a=b=13.2307(10) ?, c=19.335(2) ?, ?=?=90°, and ?=120°, and space group of P63/mmc. The invention further provides a method for preparing the two-dimensional chalcogenide and use thereof in the adsorption of iodine vapor. The two-dimensional chalcogenide of the present invention is capable of removing iodine vapor of various concentrations (as low as 400 ppm) over a wide range of temperatures (25° C.-75° C.), without desorption of iodine after standing for a long time.