Patents by Inventor Linzhu KLUKAS

Linzhu KLUKAS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for separation of racemic compound-forming chiral substances by a cyclic crystallization process and a crystallization device
    Patent number: 8822721
    Abstract: The invention concerns a method for separating a racemic compound-forming chiral substance by a cyclic crystallization process which is conducted in at least one first crystallization unit (10) and in at least one second crystallization unit (18), wherein in a first process cycle an enantiomer is crystallized in the first crystallization unit (10) and a racemic compound is crystallized in the second crystallization unit (18), wherein in a second process cycle the enantiomer is crystallized in the second crystallization unit (18) and the racemic compound is crystallized in the first crystallization unit (10), wherein during each process cycle in at least one process sub-step (B?C, F?G) a mother liquor (12) being contained in the first crystallization unit (10) is mutually exchanged with a mother liquor (20) being contained in the second crystallization unit (18). An auto-seeding process sub-step is applied at the beginning of a process cycle.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: September 2, 2014
    Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Heike Lorenz, Daniel Polenske, Linzhu Klukas, Andreas Seidel-Morgenstern
  • Method for Separation of Racemic Compound-Forming Chiral Substances by a Cyclic-Crystallization Process and a Crystallization Device
    Publication number: 20130184489
    Abstract: The invention concerns a method for separating a racemic compound-forming chiral substance by a cyclic crystallization process which is conducted in at least one first crystallization unit (10) and in at least one second crystallization unit (18), wherein in a first process cycle an enantiomer is crystallized in the first crystallization unit (10) and a racemic compound is crystallized in the second crystallization unit (18), wherein in a second process cycle the enantiomer is crystallized in the second crystallization unit (18) and the racemic compound is crystallized in the first crystallization unit (10), wherein during each process cycle in at least one process sub-step (B?C, F?G) a mother liquor (12) being contained in the first crystallization unit (10) is mutually exchanged with a mother liquor (20) being contained in the second crystallization unit (18). An auto-seeding process sub-step is applied at the beginning of a process cycle.
    Type: Application
    Filed: February 8, 2012
    Publication date: July 18, 2013
    Applicant: Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V.
    Inventors: Heike LORENZ, Daniel POLENSKE, Linzhu KLUKAS, Andreas SEIDEL-MORGENSTERN
  • Method for separation of racemic compound-forming chiral substances by a cyclic crystallization process and a crystallization device
    Publication number: 20120197040
    Abstract: The invention concerns a method for separating a racemic compound-forming chiral substance by a cyclic crystallization process which is conducted in at least one first crystallization unit (10) and in at least one second crystallization unit (18), wherein in a first process cycle an enantiomer is crystallized in the first crystallization unit (10) and a racemic compound is crystallized in the second crystallization unit (18), wherein in a second process cycle the enantiomer is crystallized in the second crystallization unit (18) and the racemic compound is crystallized in the first crystallization unit (10), wherein during each process cycle in at least one process sub-step (B?C, F?G) a mother liquor (12) being contained in the first crystallization unit (10) is mutually exchanged with a mother liquor (20) being contained in the second crystallization unit (18). An auto-seeding process sub-step is applied at the beginning of a process cycle.
    Type: Application
    Filed: February 8, 2012
    Publication date: August 2, 2012
    Inventors: Heike LORENZ, Daniel POLENSKE, Linzhu KLUKAS, Andreas SEIDEL-MORGENSTERN