Patents by Inventor Lionel Galibert

Lionel Galibert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230374540
    Abstract: “MAAP” is a naturally-occurring, newly-discovered about 13 KDa adeno-associated vims protein. It is not homologous to known proteins. When AAV producer cells are cultured for more than 24 hours, we found that inactivating translation of the full-length MAAP improves the productivity of the transfected producer cells. The resulting AAV viruses are also of better quality and more stable. Our findings thus provide a way to improve the industrial manufacture of recombinant adeno-associated virus gene therapy vectors.
    Type: Application
    Filed: June 25, 2021
    Publication date: November 23, 2023
    Inventors: Lionel GALIBERT, Kari AIRENNE, Amira HYVÖNEN, Reetta ERIKSSON, Hanna Lesch, Justin Darius ALBERS
  • Patent number: 10767192
    Abstract: The invention relates to a recombinant baculoviral genome useful for the production of viral vectors for gene therapy, allowing said production from a single infection.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: September 8, 2020
    Assignee: GENETHON
    Inventors: Lionel Galibert, Otto-Wilhelm Merten, Aurelien Jacob
  • Patent number: 10480010
    Abstract: The present invention relates to an optimized baculovirus construct useful for the production of virus(-like) particles or viral vectors, in particular viral vectors for gene therapy.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: November 19, 2019
    Assignee: GENETHON
    Inventors: Lionel Galibert, Otto-Wilhelm Merten, Monique Van Oers, Christel Riviere
  • Publication number: 20180305717
    Abstract: The invention relates to a recombinant baculoviral genome useful for the production of viral vectors for gene therapy, allowing said production from a single infection
    Type: Application
    Filed: July 9, 2018
    Publication date: October 25, 2018
    Inventors: LIONEL GALIBERT, OTTO-WILHELM MERTEN, AURELIEN JACOB
  • Patent number: 10017783
    Abstract: The invention relates to a recombinant baculoviral genome useful for the production of viral vectors for gene therapy, allowing said production from a single infection.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: July 10, 2018
    Assignee: GENETHON
    Inventors: Lionel Galibert, Otto-Wilhelm Merten, Aurélien Jacob
  • Publication number: 20140356904
    Abstract: The present invention relates to an optimized baculovirus construct useful for the production of virus (-like) particles or viral vectors, in particular viral vectors for gene therapy.
    Type: Application
    Filed: July 27, 2012
    Publication date: December 4, 2014
    Applicant: Genethon
    Inventors: Lionel Galibert, Otto-Wilhelm Merten, Monique Van Oers, Christel Riviere
  • Publication number: 20140349374
    Abstract: The invention concerns a recombinant baculovirus genome useful for the expression of gene therapy vectors by means of a single infection.
    Type: Application
    Filed: July 27, 2012
    Publication date: November 27, 2014
    Applicant: Genethon
    Inventors: Lionel Galibert, Otto-Wilhelm Merten, Aurélien Jacob