Abstract: A device for diagnosing the ventilatory efficacy of a patient under respiratory assistance, said device being intended to cooperate with a system for ventilating the patient, the device having: a bidirectional thermal mass sensor for measuring, in real time, the air flows during insufflation and during exhalation, an electronic casing connected to said sensor and configured to receive and process data relating to the air flows measured by the sensor, the electronic casing having: i. a user interface comprising a display device and data input means, ii. a data-processing center, the data-processing center functioning according to programmed algorithms for acquiring, processing and displaying the data, for analyzing the efficacy of the ventilation in real time, and for managing alarms, and iii. means for supplying electricity.

Abstract: A device for diagnosing the ventilatory efficacy of a patient under respiratory assistance, said device being intended to cooperate with a system for ventilating the patient, the device having: a bidirectional thermal mass sensor for measuring, in real time, the air flows during insufflation and during exhalation, an electronic casing connected to said sensor and configured to receive and process data relating to the air flows measured by the sensor, the electronic casing having: i. a user interface comprising a display device and data input means, ii. a data-processing center, the data-processing center functioning according to programmed algorithms for acquiring, processing and displaying the data, for analyzing the efficacy of the ventilation in real time, and for managing alarms, and iii. means for supplying electricity.

Abstract: The invention relates to a secure system for the perfusion of a body liquid, enabling a final control of compatibility of a treatment with the patient and/or the medical situation previously diagnosed by a doctor, in a simple, efficient and energy-saving manner. To this end, the system includes a fluidic circuit of a perfusion having a perfusion catheter, a perfusion tubing and a container for the determined perfusion product to be perfused to a patient. The system is also configured to take a body liquid sample from a patient and to analyze and compare the body liquid sample to the determined perfusion product so as to control the flow of the perfusion product.

Abstract: The invention relates to a device (200) for taking a sample of a body fluid, such as blood, to be incorporated into a fluid circuit of a perfusion (100) of a patient who has a perfusion catheter (104), said device having a tubular structure (202) for connecting to the fluid circuit of the perfusion, provided with a zone for intubation, during use, of a sampling channel (300) comprising a distal end (301); and a means (203) for holding, during use, in the tubular structure, the part of the sampling channel (300) comprising a distal end (301) in such a way that the distal end (301) is oriented towards the perfusion catheter (104), in the direction of flow (F1) of the perfusion product (102), from a perfusion product reservoir (101) towards the perfusion catheter (104).

Abstract: The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular matrix; at least one pluridimensional medium is soaked with said mixture; from the components of the mixture, a lattice comprising at least one element of an extracellular matrix is produced, at least at the medium; at least part of the components of said mixture is attached to the structure of the medium; the shrinking of at least the lattice is prevented and at least said lattice is tensioned on said medium; fibroblasts are integrated into the lattice and at least one cell culture of said fibroblasts is carried out, at least in the lattice. The invention also relates to a method for producing a skin equivalent that comprises at least one dermal equivalent formed by an unshrunken tissue equivalent and at least one epidermal equivalent.

Abstract: A screening tool includes: a compression body for engaging with a portion of a limb of the patient to be compressed; a compression element for compressing the contact surface against the portion of the patient's limb to be compressed; a measurement element for structurally and functionally engaging with a portion of the limb to be examined, as well as generating, via the optical detection of one or more component(s) of the blood, a measurement signal that is characteristic of an arterial pulse in the portion of the limb to be examined during a measurement phase. The compression element generates a measurement pressure substantially equal to a threshold pressure value during the entire measurement phase, and the screening tool also includes: a calculation element for transmitting a negative signal when the arterial pulse is greater than a threshold diagnostic value, and a positive signal it is lower than the threshold value.

Abstract: The invention relates to a secure system for the perfusion of a body liquid, enabling a final control of compatability of a treatment with the patient and/or the medical situation previously diagnosed by a doctor, in a simple, efficient and energy-saving manner.

Abstract: The invention relates to a device (200) for taking a sample of a body fluid, such as blood, to be incorporated into a fluid circuit of a perfusion (100) of a patient who has a perfusion catheter (104), said device having a tubular structure (202) for connecting to the fluid circuit of the perfusion, provided with a zone for intubation, during use, of a sampling channel (300) comprising a distal end (301); and a means (203) for holding, during use, in the tubular structure, the part of the sampling channel (300) comprising a distal end (301) in such a way that the distal end (301) is oriented towards the perfusion catheter (104), in the direction of flow (F1) of the perfusion product (102), from a perfusion product reservoir (101) towards the perfusion catheter (104).

Abstract: A diffusion insert (1) for a membrane (5), includes a cup (2) defining a donor compartment (20) receiving a donor solution, the base thereof defining an axial port (22) sealed by the membrane (5), a clamping element (3) to pin down the membrane (5), an element for axially locking (4) the clamping element (3), a deformation element (6) capable of deforming the membrane (5) and of protecting the lateral movement directly tangential to the deformation element (6), characterized in that the insert includes a return element (7) for deforming and radially stretching the membrane (5) in a controlled manner. A kit, a cell, a diffusion unit, and a diffusion method for implementing the diffusion insert are also disclosed.

Abstract: The invention relates to a disposable device comprising all of the reagents necessary for the detection of one or more particles of interest, and which can be incorporated in a detection system including simple means for the automatic management of fluids. For this purpose, the invention relates to a disposable device for the detection of one or more particles of interest present in a liquid sample, said device comprising a substrate provided with: a chamber for capturing the particle(s) of interest to be detected; a fluid channel connecting, upstream, the capture chamber to a buffer solution container, a liquid sample injection means and a container of labelling probes that can be secured to the particle(s) of interest to be detected; and a fluid channel connecting, downstream, the capture chamber to a container for the recovery of liquids which, during use, can flow from the capture chamber.

Abstract: The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular matrix; at least one pluridimensional medium is soaked with said mixture; from the components of the mixture, a lattice comprising at least one element of an extracellular matrix is produced, at least at the medium; at least part of the components of said mixture is attached to the structure of the medium; the shrinking of at least the lattice is prevented and at least said lattice is tensioned on said medium; fibroblasts are integrated into the lattice and at least one cell culture of said fibroblasts is carried out, at least in the lattice. The invention also relates to a method for producing a skin equivalent that comprises at least one dermal equivalent formed by an unshrunken tissue equivalent and at least one epidermal equivalent.