Patents by Inventor Lionel Rousseau
Lionel Rousseau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11534095Abstract: Flexible implant for electrically recording or stimulating a nerve structure, said flexible implant comprising: a first layer of electrically insulating diamond; an electrode of electrically conductive doped diamond, in contact with the first layer of electrically insulating diamond; an electrically conductive layer in contact with the electrode and the first layer, so as to define a conductive track for the electrode; and a second layer of electrically insulating diamond, at least in contact with the electrically conductive layer and a remaining portion of the first layer, all of the above arranged such that: electrically insulating diamond/electrically conductive doped diamond sealing is provided at the electrode (3) by resumption of epitaxial growth; and the electrically conductive layer is encapsulated by the electrode (3), the first layer and the second layer, at the electrode and over the entirety of the remaining surface thereof except over an area defining an electrical contact.Type: GrantFiled: October 25, 2018Date of Patent: December 27, 2022Inventors: Emmanuel Scorsone, Lionel Rousseau
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Publication number: 20220273220Abstract: The present invention relates to an implant adapted to be implanted at least partially in a biological tissue (20). Today's implants remain very susceptible to mechanical damage. The inventors have thus developed an implant having a greater reliability in terms of resistance to mechanical stress than existing implants, while allowing for easy connection with different parts of a biological tissue. This implant comprises an implant body (30) and a set of electrically conductive wires (55), each wire (55) comprising a first portion (65) electrically connected to the body (30), a second portion (70) and a third portion (75) intended to be electrically connected to the tissue (20), The implant (10) comprises a set of arms (25) comprising each an insulating sheath (60) and a bundle (52) of wires (55), each bundle (52) comprising at least two subsets (62) of wires (55).Type: ApplicationFiled: July 15, 2020Publication date: September 1, 2022Inventors: Fannie DARLOT, Gaëlle OFFRANC PIRET, Lionel ROUSSEAU, Paul VILLARD
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Patent number: 11286472Abstract: The present invention relates to the expression and optimization of enzymes involved in the breakdown of lignocellulosic biomass. Disclosed are variants of the exoglucanase 1 of Trichoderma reesei, as well as the use of said variants with improved efficiency in methods for breaking down cellulose and for producing biofuel.Type: GrantFiled: February 21, 2020Date of Patent: March 29, 2022Assignees: IFP Energies nouvelles, ProteusInventors: Cecile Persillon, Christophe Ullmann, Celine Ayrinhac, Olivier Bonzom, Sebastien Fort, Sylvie Armand, Stephanie Pradeau, Antoine Margeot, Lionel Rousseau, Françoise Le Roux
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Publication number: 20210177333Abstract: Flexible implant for electrically recording or stimulating a nerve structure, said flexible implant comprising: a first layer of electrically insulating diamond; an electrode of electrically conductive doped diamond, in contact with the first layer of electrically insulating diamond; an electrically conductive layer in contact with the electrode and the first layer, so as to define a conductive track for the electrode; and a second layer of electrically insulating diamond, at least in contact with the electrically conductive layer and a remaining portion of the first layer, all of the above arranged such that: electrically insulating diamond/electrically conductive doped diamond sealing is provided at the electrode (3) by resumption of epitaxial growth; and the electrically conductive layer is encapsulated by the electrode (3), the first layer and the second layer, at the electrode and over the entirety of the remaining surface thereof except over an area defining an electrical contact.Type: ApplicationFiled: October 25, 2018Publication date: June 17, 2021Applicants: Chambre de Commerce et D'Industrie de Region Paris Ile de France, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Emmanuel Scorsone, Lionel Rousseau
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Publication number: 20200347371Abstract: The present invention relates to the expression and optimisation of enzymes involved in the breakdown of lignocel-lulosic biomass. The present invention specifically relates to variants of the exoglucanase 1 of Trichoderma reesei, as well as to the use of said variants with improved efficiency in methods for breaking down cellulose and for producing biofuel.Type: ApplicationFiled: February 21, 2020Publication date: November 5, 2020Inventors: Cecile PERSILLON, Christophe ULLMANN, Celine AYRINHAC, Olivier BONZOM, Sebastien FORT, Sylvie ARMAND, Stephanie PRADEAU, Antoine MARGEOT, Lionel ROUSSEAU, Françoise LE ROUX
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Patent number: 10745679Abstract: The present invention relates to the expression and optimization of enzymes involved in the breakdown of lignocellulosic biomass. Disclosed are variants of the exoglucanase 1 of Trichoderma reesei, as well as the use of said variants with improved efficiency in methods for breaking down cellulose and for producing biofuel.Type: GrantFiled: June 12, 2015Date of Patent: August 18, 2020Assignees: IFP Energies Nouvelles, Centre National De La Recherche Scientifique—CNRS, ProteusInventors: Cecile Persillon, Christophe Ullmann, Celine Ayrinhac, Olivier Bonzom, Sebastien Fort, Sylvie Armand, Stephanie Pradeau, Antoine Margeot, Lionel Rousseau, Françoise Le Roux
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Patent number: 10639472Abstract: The invention relates to a process for manufacturing at least one implant for focal electrical stimulation of a nervous structure, said implant being of the type including in a supporting structure a network of cavities at the bottom of which are placed microelectrodes, the cavities being bounded by walls erected and located around the microelectrodes, the supporting structure being produced beforehand by implementing the following steps: deposition and etching, in a planar manner, on an insulating substrate, of electrical contacts, of electrical tracks and of microelectrodes, first tracks electrically connecting the microelectrodes and the electrical contacts, second electrical tracks being electrically connected to a ground.Type: GrantFiled: November 19, 2015Date of Patent: May 5, 2020Assignees: Chambre de Commerce et D'Industrie de Region Paris Ile de France (ESIEE Paris), Universite Pierre Et Marie Curie (Paris 6), Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante et de la Recherche Medicale (INSERM)Inventors: Lionel Rousseau, Gaëlle Lissorgues, Myline Cottance, Serge Picaud, Julie Degardin
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Publication number: 20190083776Abstract: The invention relates to a process for manufacturing at least one implant for focal electrical stimulation of a nervous structure, said implant being of the type including in a supporting structure a network of cavities at the bottom of which are placed microelectrodes, the cavities being bounded by walls erected and located around the microelectrodes, the supporting structure being produced beforehand by implementing the following steps: deposition and etching, in a planar manner, on an insulating substrate, of electrical contacts, of electrical tracks and of microelectrodes, first tracks electrically connecting the microelectrodes and the electrical contacts, second electrical tracks being electrically connected to a ground.Type: ApplicationFiled: November 19, 2015Publication date: March 21, 2019Applicants: Chambre de Commerce et D'Industrie de Region Paris Ile de France (ESIEE Paris), Universite Pierre Et Marie Curie (Paris 6), Centre National de la Recherche Scientifique (CNRS ), Institut National de la Sante et de la Recherche M edicale (INSERM)Inventors: Lionel Rousseau, Gaëlle Lissorgues, Myline Cottance, Serge Picaud, Julie Degardin
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Publication number: 20180209941Abstract: A device for detecting and/or measuring out one or more chemical compounds and a cell for forming the device, the device including at least one first and one second vibrating surface, each having a resonance frequency which varies when placed in presence of at least one chemical compound to be detected, and at least one first system actuating the first and the second vibrating surface to vibrate the first vibrating surface. The first actuating system is configured to generate a first mechanical wave remote from the first and the second vibrating surface, the first actuating system arranged in the device such that the first mechanical wave is transmitted to the first and the second vibrating surfaces to vibrate the first and the second vibrating surfaces.Type: ApplicationFiled: April 2, 2015Publication date: July 26, 2018Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Emmanuel SCORSONE, Bertrand BAZIN, Farbod GHASSEMI, Gaelle LISSORGUES, Rafa MANAI, Krishna PERSAUD, Lionel ROUSSEAU
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Publication number: 20170152497Abstract: The present invention relates to the expression and optimisation of enzymes involved in the breakdown of lignocellulosic biomass. The present invention specifically relates to variants of the exoglucanase 1 of Trichoderma reesei, as well as to the use of said variants with improved efficiency in methods for breaking down cellulose and for producing biofuel.Type: ApplicationFiled: June 12, 2015Publication date: June 1, 2017Inventors: Cecile PERSILLON, Christophe ULLMANN, Celine AYRINHAC, Olivier BONZOM, Sebastien FORT, Sylvie ARMAND, Stephanie PRADEAU, Antoine MARGEOT, Lionel ROUSSEAU, Françoise LE ROUX
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Patent number: 9559290Abstract: A method for producing a piezoelectric sensor, includes the following steps: producing, on a rigid support (10), a stack of sensor layers (2, 4, 5, 12), the sensor layers including a layer of piezoelectric material (5) included between a first electrode (6, 7) and a second electrode (8, 9), the first electrode not being in contact with the second electrode, then, while the sensor layers (2, 4, 5, 12) are still held by the rigid support (10), covering the sensor layers with a polymer layer (11), then removing the stack of sensor layers from the rigid support (10), such that the sensor layers covered by the polymer layer (11) are no longer carried by the rigid support (10).Type: GrantFiled: May 23, 2014Date of Patent: January 31, 2017Assignees: CHAMBRE DE COMMERCE ET D'INDUSTRIE DE REGION PARIS ILE DE FRANCE, BODY CAPInventors: Laurie Valbin, Lionel Rousseau, Fabrice Verjus
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Publication number: 20160287113Abstract: A microelectrode (2) for neural interfacing applications comprises a first substrate layer (4), a second attachment layer (6), and a third layer (8) forming the active part of the electrode (2) of which the material consists of synthetic diamond made in electrically conductive by doping with atoms chosen from boron, nitrogen and phosphorus atoms. The material of the third layer (8) is a textured material that comprises a compact assembly, in the form of a brush, of tubes (26) each comprising, in the form of at in least one peripheral outer layer, polycrystalline diamond made electrically conductive by doping. The tubes (26) are separated from each other at the first fixed ends (28) of same and project the free ends (30) of same away from the first and second layers (4, 6) in a direction that is substantially vertical relative to the extension plane (20) of the second layer (6). A method for producing said microelectrode is also described.Type: ApplicationFiled: October 14, 2014Publication date: October 6, 2016Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Clément Hebert, Emmanuel Scorsone, Jean-Paul Mazellier, Lionel Rousseau
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Publication number: 20160172578Abstract: A method for producing a piezoelectric sensor, includes the following steps: producing, on a rigid support (10), a stack of sensor layers (2, 4, 5, 12), the sensor layers including a layer of piezoelectric material (5) included between a first electrode (6, 7) and a second electrode (8, 9), the first electrode not being in contact with the second electrode, then, while the sensor layers (2, 4, 5, 12) are still held by the rigid support (10), covering the sensor layers with a polymer layer (11), then removing the stack of sensor layers from the rigid support (10), such that the sensor layers covered by the polymer layer (11) are no longer carried by the rigid support (10).Type: ApplicationFiled: May 23, 2014Publication date: June 16, 2016Inventors: Laurie VALBIN, Lionel ROUSSEAU, Fabrice VERJUS
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Patent number: 8801942Abstract: A method for manufacturing an intraocular retinal implant including: providing a mold capable of supporting growth of a layer of doped diamond, the mold including, on one face, elements all depressed or all projecting with respect to the surface of the face, and constituting a pattern cavity for the electrodes of the implant which it is desired to obtain; producing the doped diamond electrodes by growing a layer of doped diamond in all or part of a space occupied by the pattern cavity elements; forming a first insulating layer on the face of the mold including the pattern cavity; producing interconnection lines by depositing an electrically conductive material at least in spaces not covered by the first insulating layer; forming a second insulating layer on the mold face including the pattern cavity, the second layer covering the interconnection lines, the first and second insulating layers forming a flexible plate of the implant; removing the mold.Type: GrantFiled: June 8, 2011Date of Patent: August 12, 2014Assignees: Commissariat a l'energie atomique et aux energies alternatives, Chambre de Commerce et d'Industrie de Paris (ESIEE Paris)Inventors: Emmanuel Scorsone, Philippe Bergonzo, Gaelle Lissorgues, Lionel Rousseau, Michel Bonnauron, Christine Alice Regine Helene Terrades, Serge Anne Daniel Bonnauron, Lucas Claude Jean Francois Bonnauron, Tanguy Richard Yves Bonnauron
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Patent number: 8774938Abstract: The invention relates to an implant which includes, in order to electrically stimulate a nerve structure, in particular the retina, an electrically insulating substrate (1), a array of recesses (2) formed in an upper surface of the substrate, stimulation electrodes (3) arranged at the bottom of the recesses, and an electrically conductive layer forming a ground plane (4) at the upper portion of the recesses. The sizes of the recesses and of the electrodes of the implant are such that the spatial selectivity of the stimulation current applied to the nerve structure is maximized.Type: GrantFiled: April 29, 2011Date of Patent: July 8, 2014Assignee: Universite Pierre et Marie Curie (Paris 6)Inventors: Henri Lorach, Milan Djilas, Blaise Yvert, Philippe Bergonzo, Gaelle Lissorgues, Lionel Rousseau, Ryad Benjamin Benosman, Serge Picaud, Jose Sahel, Siohoi Ieng
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Publication number: 20130225968Abstract: The invention relates to a sensing means for a contact lens used in a physiological parameter measuring system comprising one or two contact lenses, wherein to improve the comfort of wear for a patient each contact lens comprises an antenna and a purely passive sensing means. The invention also relates to a corresponding method and a method to fabricate the sensing means and the contact lens.Type: ApplicationFiled: July 28, 2011Publication date: August 29, 2013Applicant: OPHTIMALIAInventors: Philippe Auvray, Gaelle Lissorgues, Lionel Rousseau
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Publication number: 20130096660Abstract: The invention relates to an implant which includes, in order to electrically stimulate a nerve structure, in particular the retina, an electrically insulating substrate (1), a array of recesses (2) formed in an upper surface of the substrate, stimulation electrodes (3) arranged at the bottom of the recesses, and an electrically conductive layer forming a ground plane (4) at the upper portion of the recesses.Type: ApplicationFiled: April 29, 2011Publication date: April 18, 2013Applicant: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)Inventors: Henri Lorach, Milan Djilas, Blaise Yvert, Philippe Bergonzo, Gaelle Lissorgues, Lionel Rousseau, Ryad Benjamin Benosman, Serge Picaud, Jose Sahel, Siohoi Ieng
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Patent number: 8352045Abstract: The disclosure relates to a device for stimulating living tissue, comprising an array of stimulating microelectrodes that are placed in a defined configuration side by side and able to be selected by applying an electrical signal for stimulation by one of the microelectrodes. According to the disclosure, an additional conducting surface for application against the living tissue, is provided in the vicinity of a defined plurality of sections for local application of microelectrodes, connecting structures being provided for electrical connection between the zones, and the additional conducting surface being also connected to a lead and being formed so as to ensure local stimulation via a microelectrode.Type: GrantFiled: October 20, 2008Date of Patent: January 8, 2013Assignees: Centre National de la Recherche Scientifique (CNRS), Group Ecole Superieure d'Ingenieurs en Electronique et Electrotechnique, Universite de Bordeaux 1Inventors: Sébastien Joucla, Blaise Yvert, Lionel Rousseau
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Patent number: 8038342Abstract: The present invention relates to a method for determining the kinetics of gas hydrate formation in a fluid comprising water, wherein the following stages are carried out: a sample of the fluid is provided in form of a water-in-oil stable emulsion, DSC measurements are performed on the sample to obtain at least one peak corresponding to the gas hydrate conversion energy in the water drops of said emulsion, kinetic characteristics of the formation of hydrates in said fluid are deduced from the peak.Type: GrantFiled: May 24, 2006Date of Patent: October 18, 2011Assignee: Institut Francais du PetroleInventors: Christine Dalmazzone, Benjamin Herzhaft, Lionel Rousseau
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Publication number: 20110208029Abstract: The disclosure relates to a device for stimulating living tissue, comprising an array of stimulating microelectrodes that are placed in a defined configuration side by side and able to be selected by applying an electrical signal for stimulation by one of the microelectrodes. According to the disclosure, an additional conducting surface for application against the living tissue, is provided in the vicinity of a defined plurality of sections for local application of microelectrodes, connecting means being provided for electrical connection between the zones, and the additional conducting surface being also connected to a lead and being formed so as to ensure local stimulation via a microelectrode.Type: ApplicationFiled: October 20, 2008Publication date: August 25, 2011Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENFIFIQUE (CNRS), GROUPE ECOLE SUPERIEURE D'INGENIEURS EN ELECTRONIQUE ET ELECTROTECHNIQUE, UNIVERSITE DE BORDEAUX 1Inventors: Sébastien Joucla, Blaise Yvert, Lionel Rousseau