Abstract: The present invention relates to the field of bio-pharmaceuticals and, in particular, to an anti-Siglec-15 antibody or an antigen binding fragment thereof, a nucleic acid sequence encoding the anti-Siglec-15 antibody of the present invention or an antigen binding fragment thereof, an expression vector containing the nucleic acid sequence, a host cell containing the expression vector, a composition or a bispecific antibody comprising the anti-Siglec-15 antibody of the present invention or an antigen binding fragment thereof, an immune conjugate comprising the anti-Siglec-15 antibody of the present invention or an antigen binding fragment thereof linked to a therapeutic agent, as well as use of the anti-Siglec-15 antibody of the present invention or an antigen binding fragment thereof in the preparation of a medicament for treatment of cancer.

Abstract: Some embodiments of a disclosure provide a piston limiting structure, a compressor, and a heat exchange apparatus. The piston limiting structure includes: a cylinder, having a piston hole perpendicular to an axial direction of the cylinder and penetrating the cylinder, wherein a projection of the piston hole in a penetrating direction is circular; a piston, disposed in the piston hole and slid in the piston hole, wherein a side wall of the piston is provided with a limiting surface, and the limiting surface does not penetrate two ends of the side wall of the piston along an axial length of the piston; and a limiting member, wherein the cylinder is provided with a limiting hole penetrating from an outer wall of the cylinder to the piston hole, the limiting member is mounted in the limiting hole, and the limiting member abuts against the limiting surface.

Abstract: A method and apparatus for differentially optimizing a quality of service (QoS) includes: establishing a system model of a multi-task unloading framework; acquiring a mode for users executing a computation task, executing, according to the mode for users executing the computation task, the system model of the multi-task unloading framework; and optimizing a quality of service (QoS) on the basis of a multi-objective optimization method for a multi-agent deep reinforcement learning.

Abstract: A method and apparatus for differentially optimizing a quality of service (QoS) includes: establishing a system model of a multi-task unloading framework; acquiring a mode for users executing a computation task, executing, according to the mode for users executing the computation task, the system model of the multi-task unloading framework; and optimizing a quality of service (QoS) on the basis of a multi-objective optimization method for a multi-agent deep reinforcement learning.

Abstract: Some embodiments of a disclosure provide a piston limiting structure, a compressor, and a heat exchange apparatus. The piston limiting structure includes: a cylinder, having a piston hole perpendicular to an axial direction of the cylinder and penetrating the cylinder, wherein a projection of the piston hole in a penetrating direction is circular; a piston, disposed in the piston hole and slid in the piston hole, wherein a side wall of the piston is provided with a limiting surface, and the limiting surface does not penetrate two ends of the side wall of the piston along an axial length of the piston; and a limiting member, wherein the cylinder is provided with a limiting hole penetrating from an outer wall of the cylinder to the piston hole, the limiting member is mounted in the limiting hole , and the limiting member abuts against the limiting surface.

Abstract: Provided is a piston limiting structure, including: a cylinder, a piston, and a flange provided with a limiting piece, the cylinder has a piston hole perpendicular to an axial direction of the cylinder and penetrating through the cylinder, and a projection of the piston hole in a penetrating direction is circular; the piston is disposed in the piston hole in a form-fit manner and is slid in the piston hole in a reciprocating manner, a side wall of the piston is provided with a thrust groove, a bottom surface of the thrust groove forms a thrust surface on the side wall of the piston, and the thrust groove does not penetrate through two ends of the side wall of the piston along an axial length of the piston; and the limiting piece abuts against the thrust surface.

Abstract: Disclosed is a compressor, including a crankshaft (10), and a first cylinder (20), a second cylinder (30) and a third cylinder (40) arranged sequentially in an axial direction of the crankshaft (10). The first cylinder (20) is a high-pressure cylinder, and the second cylinder (30) and the third cylinder (40) are low-pressure cylinders. The compressor also comprises a capacity variation switching mechanism (50) for controlling loading and unloading of the third cylinder (40). The compressor has a full operation mode and a partial operation mode. By means of the capacity variation switching mechanism (50) provided in the compressor, at least one cylinder is allowed to be put into use or unloaded under the action of the capacity variation switching mechanism (50), thus enabling a capacity variation switching function of the compressor to meet operational requirements of different operating conditions.