Patents by Inventor Liping Zhao
Liping Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11963534Abstract: An application of fengycin family lipopeptides in pest control is provided, and Fengycin family lipopeptides are used for pest control, with especially strong killing effects on Homoptera and Coleoptera pests. A method is provided for treating seeds with fengycin to protect seeds and plant organs formed later from pests, so as to protect seeds from pests by coating the fengycin family lipopeptides on the surface of seeds.Type: GrantFiled: November 18, 2022Date of Patent: April 23, 2024Assignee: INSTITUTE OF BIOLOGY, HEBEI ACADEMY OF SCIENCESInventors: Hongwei Liu, Caimiao Yao, Yongfeng Liu, Liping Zhang, Yana Wang, Wenya Zhao
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Publication number: 20240092038Abstract: A device for manufacturing a storage container by integrally winding multiple bundles of fibers in a double-layer spiral circumferential direction. The device includes a rotary drive unit and two radial slide drive units provided at two sides of the rotary drive unit, each of the two radial slide drive units is provided with several spiral winding guide wire tubes in a circumferential array and drives the spiral winding guide wire tubes to perform a radial telescopic movement, the rotary drive unit drives the spiral winding guide wire tubes on the two radial slide drive units to perform a rotation movement, the rotary drive unit is connected to the two radial slide drive units by means of brackets, and a rack plate is connected to one side of each of the two radial slide drive units away from the rotary drive unit.Type: ApplicationFiled: November 14, 2023Publication date: March 21, 2024Inventors: Jianguo LIANG, Qingxue HUANG, Yujie DUAN, Yinhui LI, Chunjiang ZHAO, Jun FENG, Liping BIAN, Haixia ZHANG, Yanchun ZHU, Yuqin XUE
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Publication number: 20240082166Abstract: An oral capsule formulation of a PARP inhibitor and a preparation method. The oral capsule formulation comprises a solid dispersion powder of an active ingredient 5-fluoro-1-(4-fluoro-3-(4-(pyrimidin-2-yl)piperazine-1-carbonyl)benzyl)quinazoline-2,4(1H,3H)-dione, a filler, a disintegrant, a glidant, and a lubricant, wherein less than 10 wt. % of the active ingredient in the solid dispersion powder is in a crystalline form. The defects of the fluidity, hygroscopicity and cohesiveness of the solid dispersion powder which result in the difficulty of production scale up of capsule formulation are addressed, and thus commercial scale production can be achieved, and the prepared capsule exhibits proper dissolution rate, excellent storage stability, meanwhile with a reasonable production cost.Type: ApplicationFiled: March 25, 2022Publication date: March 14, 2024Inventors: Sui Xiong CAI, Ning MA, Liping ZHAO, Chunhui LIU, Zongfeng SHI
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Publication number: 20240059568Abstract: An apparatus, a process and a system for treating petroleum coke are provided. The apparatus includes an activation unit that is an annular furnace reactor. The system includes a first reactor, the apparatus as a second reactor, a washing and separating unit, a cooling unit, a dissolving and separating unit, a washing and drying unit, optionally a regenerating unit, optionally a drying and calcining unit and optionally an evaporation-crystallization unit. The process for producing carbon materials uses the system for treating petroleum coke. The apparatus, the process and the system can achieve continuous production, and have advantages of high activation efficiency and stable properties of the resultant carbon material products.Type: ApplicationFiled: January 10, 2022Publication date: February 22, 2024Inventors: Shudong ZHANG, Changan ZHANG, Yongyi SONG, Jihua LIU, Xiangchen FANG, Rui MA, Haile CAI, Liping ZHAO, Changjian LIAO, Fanfei MENG, Haibo WANG, Qingjun ZHANG, Chao WANG
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Patent number: 11842642Abstract: The invention provides designs and methods for a heavy vehicle operations and control system for heavy automated vehicles, which facilitates heavy vehicle operation and control for connected automated vehicle highway (CAVH) systems. The heavy vehicle management system provides heavy vehicles with individually customized information and real-time vehicle control instructions to fulfill the driving tasks such as car following, lane changing, route guidance. The heavy vehicle management system also realizes heavy vehicle related lane design, transportation operations, and management services for both dedicated and non-dedicated lanes. The heavy vehicle management system consists of one or more of the following physical subsystems: (1) Roadside unit (RSU) network, (2) Traffic Control Unit (TCU) and Traffic Control Center (TCC) network, (3) vehicles and onboard units (OBU), (4) traffic operations centers (TOCs), and (5) cloud platform.Type: GrantFiled: June 19, 2019Date of Patent: December 12, 2023Assignee: CAVH LLCInventors: Bin Ran, Yang Cheng, Kun Luan, Haiyan Yu, Yi Shen, Shiyan Xu, Xiaoli Zhang, Hongli Gao, Shaohua Wang, Hongliang Wan, Linchao Li, Linghui Xu, Liling Zhu, Linfeng Zhang, Yifei Wang, Qin Li, Yanyan Qin, Hainan Huang, Dongye Sun, Liping Zhao
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Patent number: 11820995Abstract: A method for creating a new germplasm of a male sterile crop by gene editing and an application thereof are provided. In this method, the gene editing is performed on an exon region of a Ty-5 gene, and a deletion of DNA sequence is introduced by using a repair mechanism of plants themselves to double-strand breaks (DSBs), causing a loss of function of Ty-5 gene, thereby obtaining a male-sterile character. The method can be applied without being limited by crop categories. After the gene editing is performed on Ty-5 genes of various crops, new germplasms can be quickly obtained. The new germplasms have the same agronomic characters as the previous materials, and only differ in sexual aspect, which effectively solves the problem of the lack of male sterile materials and unstable fertility in natural resources.Type: GrantFiled: December 7, 2021Date of Patent: November 21, 2023Assignee: JIANGSU ACADEMY OF AGRICULTURAL SCIENCESInventors: Yinlei Wang, Tongmin Zhao, Wengui Yu, Liping Zhao, Rong Zhou, Liuxia Song
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Publication number: 20230142707Abstract: The present disclosure relates to a fiber mix formulation comprising a mixture of bran, inulin, and digestion resistant maltodextrin useful to restore a healthier gut microbiota and alleviate symptoms in subjects with imbalance of gut microbiota. The mixture of soluble dietary fiber (SDF) and insoluble dietary fiber (ISDF) with a ratio of ISDF:SDF (0.5:1 to 1:0.5), has synergistic effect on gut microbiota composition, promoting the growth of the acetate- and butyrate-producing bacteria and inhibiting the growth of pathogens and detrimental bacteria.Type: ApplicationFiled: April 7, 2021Publication date: May 11, 2023Inventors: Liping ZHAO, Yan LAM, Yongjia GONG, Guojun WU, Cuiping ZHAO
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Patent number: 11607435Abstract: This invention relates to novel probiotic Bifidobacteria strains, particularly, B. pseudocatenulatum strains, and their use as probiotic, and food products, feed products, dietary supplements and pharmaceutical formulations containing them. The bacteria are suitable for the treatment of obesity, diabetes, and related conditions.Type: GrantFiled: February 10, 2017Date of Patent: March 21, 2023Assignee: PERFECT (CHINA) CO., LTD.Inventors: Liping Zhao, Guojun Wu, Menghui Zhang, Chenhong Zhang, Huan Wu
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Patent number: 11471462Abstract: The invention features compositions and methods that are useful for increasing the level or activity of SLC16A11 in a subject, there by treating or preventing type 2 diabetes in the subject.Type: GrantFiled: June 27, 2017Date of Patent: October 18, 2022Assignees: THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGEInventors: Eitan Hoch, Suzanne Beth Rosenberg Jacobs, Victor Rusu, Liping Zhao, Jose M. Mercader Bigas
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Patent number: 11373730Abstract: A method in which a microorganism operational taxonomic unit (OTU) in a sample is defined based on a DNA sequence of a system generation information gene of microorganism in the sample. In the method, qualified sequence segments are obtained by means of processing and reading of an original sequence; the segments are sorted according to a relative abundance value of each segment; and only the qualified sequences with the high abundance values are used to obtain the temporary OTU. The qualified sequences with the low abundance values are reallocated; and the qualified sequence can be distributed to the proper temporary OTU respectively when a sequence similarity degree between the qualified sequence and an OTU sequence reaches at least 97%. The present disclosure also provides a sequence-assisted microorganism separation method.Type: GrantFiled: November 16, 2018Date of Patent: June 28, 2022Assignee: Perfect (China) Co., Ltd.Inventors: Liping Zhao, Jing Wang, Menghui Zhang
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Publication number: 20220112513Abstract: A method for creating a new germplasm of a male sterile crop by gene editing and an application thereof are provided. In this method, the gene editing is performed on an exon region of a Ty-5 gene, and a deletion of DNA sequence is introduced by using a repair mechanism of plants themselves to double-strand breaks (DSBs), causing a loss of function of Ty-5 gene, thereby obtaining a male-sterile character. The method can be applied without being limited by crop categories. After the gene editing is performed on Ty-5 genes of various crops, new germplasms can be quickly obtained. The new germplasms have the same agronomic characters as the previous materials, and only differ in sexual aspect, which effectively solves the problem of the lack of male sterile materials and unstable fertility in natural resources.Type: ApplicationFiled: December 7, 2021Publication date: April 14, 2022Applicant: JIANGSU ACADEMY OF AGRICULTURAL SCIENCESInventors: Yinlei WANG, Tongmin ZHAO, Wengui YU, Liping ZHAO, Rong ZHOU, Liuxia SONG
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Patent number: 11236358Abstract: A method for creating a new germplasm of a male sterile crop by gene editing and an application thereof are provided. In this method, the gene editing is performed on an exon region of a Ty-5 gene, and a deletion of DNA sequence is introduced by using a repair mechanism of plants themselves to double-strand breaks (DSBs), causing a loss of function of Ty-5 gene, thereby obtaining a male-sterile character. The method can be applied without being limited by crop categories. After the gene editing is performed on Ty-5 genes of various crops, new germplasms can be quickly obtained. The new germplasms have the same agronomic characters as the previous materials, and only differ in sexual aspect, which effectively solves the problem of the lack of male sterile materials and unstable fertility in natural resources.Type: GrantFiled: September 20, 2018Date of Patent: February 1, 2022Assignee: JIANGSU ACADEMY OF AGRICULTURAL SCIENCESInventors: Yinlei Wang, Tongmin Zhao, Wengui Yu, Liping Zhao, Rong Zhou, Liuxia Song
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Publication number: 20210236273Abstract: Tubular prostheses are provided for use in airways, upper digestive, and urinary tracts. Each of these uses has its own specific sets of biological specifications, based on what it must contain and exclude and the physical and chemical pressures and stresses to which it is subjected. The prostheses may be made from allogeneic cells. Thus they can be manufactured and stored prior to an individual's personal need arising.Type: ApplicationFiled: April 21, 2021Publication date: August 5, 2021Applicants: Humacyte, Inc., Yale UniversityInventors: Laura Niklason, Angela Huang, Liping Zhao, Shannon Dahl
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Patent number: 11058534Abstract: Tubular prostheses are provided for use in airways, upper digestive, and urinary tracts. Each of these uses has its own specific sets of biological specifications, based on what it must contain and exclude and the physical and chemical pressures and stresses to which it is subjected. The prostheses may be made from allogeneic cells. Thus they can be manufactured and stored prior to an individual's personal need arising.Type: GrantFiled: November 7, 2018Date of Patent: July 13, 2021Assignees: Humacyte, Inc, Yale UniversityInventors: Laura Niklason, Angela Huang, Liping Zhao, Shannon Dahl
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Publication number: 20210115470Abstract: A method for creating a new germplasm of a male sterile crop by gene editing and an application thereof are provided. In this method, the gene editing is performed on an exon region of a Ty-5 gene, and a deletion of DNA sequence is introduced by using a repair mechanism of plants themselves to double-strand breaks (DSBs), causing a loss of function of Ty-5 gene, thereby obtaining a male-sterile character. The method can be applied without being limited by crop categories. After the gene editing is performed on Ty-5 genes of various crops, new germplasms can be quickly obtained. The new germplasms have the same agronomic characters as the previous materials, and only differ in sexual aspect, which effectively solves the problem of the lack of male sterile materials and unstable fertility in natural resources.Type: ApplicationFiled: September 20, 2018Publication date: April 22, 2021Applicant: JIANGSU ACADEMY OF AGRICULTURAL SCIENCESInventors: Yinlei WANG, Tongmin ZHAO, Wengui YU, Liping ZHAO, Rong ZHOU, Liuxia SONG
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Publication number: 20200377945Abstract: The present invention provides a method for assessing the presence or the risk of development of type 2 diabetes mellitus in a subject based on abundance data of several CAGs. Also provided is a method for evaluating efficacy of diet intervention or disease treatment in a subject having type 2 diabetes mellitus based on abundance data of these CAGs.Type: ApplicationFiled: January 29, 2019Publication date: December 3, 2020Applicant: PERFECT (CHINA) CO., LTDInventors: Liping ZHAO, Chenhong ZHANG, Guojun WU, Menghui ZHANG
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Patent number: 10820016Abstract: Provided is an encoding and decoding method and device for data compression. The encoding method includes: adaptively selecting a constrained string mode from a plurality of preset constrained string modes; and performing, according to the selected constrained string mode, string-matching encoding on a coding block to obtain information of a constrained string encoded in the selected constrained string mode and to obtain a bitstream of a syntax element of the constrained string encoded in the selected constrained string mode.Type: GrantFiled: February 10, 2017Date of Patent: October 27, 2020Assignees: Tongji University, ZTE CorporationInventors: Tao Lin, Liping Zhao, Kailun Zhou, Shuhui Wang, Ming Li, Ping Wu, Zhao Wu
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Publication number: 20200069746Abstract: This invention relates to novel probiotic Bifidobacteria strains, particularly, B. pseudocatenulatum strains, and their use as probiotic, and food products, feed products, dietary supplements and pharmaceutical formulations containing them. The bacteria are suitable for the treatment of obesity, diabetes, and related conditions.Type: ApplicationFiled: February 10, 2017Publication date: March 5, 2020Inventors: Liping ZHAO, Guojun WU, Menghui ZHANG, Chenhong ZHANG, Huan WU
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Publication number: 20190392712Abstract: The invention provides designs and methods for a heavy vehicle operations and control system for heavy automated vehicles, which facilitates heavy vehicle operation and control for connected automated vehicle highway (CAVH) systems. The heavy vehicle management system provides heavy vehicles with individually customized information and real-time vehicle control instructions to fulfill the driving tasks such as car following, lane changing, route guidance. The heavy vehicle management system also realizes heavy vehicle related lane design, transportation operations, and management services for both dedicated and non-dedicated lanes. The heavy vehicle management system consists of one or more of the following physical subsystems: (1) Roadside unit (RSU) network, (2) Traffic Control Unit (TCU) and Traffic Control Center (TCC) network, (3) vehicles and onboard units (OBU), (4) traffic operations centers (TOCs), and (5) cloud platform.Type: ApplicationFiled: June 19, 2019Publication date: December 26, 2019Inventors: Bin Ran, Yang Cheng, Kun Luan, Haiyan Yu, Yi Shen, Shiyan Xu, Xiaoli Zhang, Hongli Gao, Shaohua Wang, Hongliang Wan, Linchao Li, Linghui Xu, Liling Zhu, Linfeng Zhang, Yifei Wang, Qin Li, Yanyan Qin, Hainan Huang, Dongye Sun, Liping Zhao
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Patent number: D870579Type: GrantFiled: August 8, 2018Date of Patent: December 24, 2019Assignee: OHAUS Instruments (Changzhou) Co. Ltd.Inventors: Zehua Zong, Liping Zhao