Patents by Inventor Liqin Chen
Liqin Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11945792Abstract: The present invention relates to various crystalline forms of 6-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide. The present invention also relates to pharmaceutical compositions comprising the crystalline forms.Type: GrantFiled: March 3, 2021Date of Patent: April 2, 2024Assignee: Beijing Innocare Pharma Tech Co., LtdInventors: Xiangyang Chen, Zuopeng Wang, Liqin Yu
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Patent number: 8137600Abstract: Injection molding systems and methods useful for making microcellular foamed materials are provided as well as microcellular articles. Pressure drop rate and shear rate are important features in some embodiments, and the invention provides systems for controlling these parameters in an injection molding system. Another aspect involves an injection molding system including a nucleator that is upstream of a pressurized mold. Another aspect involves an extrusion system with the reciprocating screw for forming a single phase solution of non-nucleated blowing agent and polymeric material. Another aspect involves very thin walled microcellular material and very thin walled polymeric material. Another aspect provides a method for producing high weight reductions in very thin-walled parts with surfaces that have no noticeable differences from non-foamed parts.Type: GrantFiled: August 20, 2007Date of Patent: March 20, 2012Assignee: Trexel, Inc.Inventors: David E. Pierick, Jere R. Anderson, Sung Woon Cha, Liqin Chen, James F. Stevenson, Dana E. Laing
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Patent number: 7473799Abstract: A process for the preparation of disubstituted adamantine derivatives characterized by the factor that the aromatic receptors can be a series of halide anisole, phenol, toluene, naphthalene, thiophene, or furan and their substituted derivatives. The synthesized disubstituted adamantine derivatives were subsequently converted into a new class of synthetic retinoids of pharmaceutical importance.Type: GrantFiled: January 29, 2007Date of Patent: January 6, 2009Assignee: Nanjing University of Aeronautics and AstronauticsInventors: Liqin Chen, Lei Tian, Xiaoquan Yao
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Publication number: 20080226892Abstract: Polymer molding processes, such as injection-molding processes, include use of a viscosity-reducing supercritical fluid additive resulting in less breakage of reinforcing fibers upon introduction into the mold.Type: ApplicationFiled: March 20, 2008Publication date: September 18, 2008Applicant: Trexel, Inc.Inventors: Levi A. Kishbaugh, Kevin J. Levesque, Albert H. Guillemette, Liqin Chen, Jingyi Xu, Kelvin T. Okamoto
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Publication number: 20080108848Abstract: A process for the preparation of disubstituted adamantine derivatives characterized by the factor that the aromatic receptors can be a series of halide anisole, phenol, toluene, naphthalene, thiophene, or furan and their substituted derivatives. The synthesized disubstituted adamantine derivatives were subsequently converted into a new class of synthetic retinoids of pharmaceutical importance.Type: ApplicationFiled: January 29, 2007Publication date: May 8, 2008Inventors: Liqin Chen, Lei Tian, Xiaoquan Yao
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Patent number: 7364788Abstract: Polymer molding processes, such as injection-molding processes, include use of a viscosity-reducing supercritical fluid additive resulting in less breakage of reinforcing fibers upon introduction into the mold.Type: GrantFiled: December 23, 2003Date of Patent: April 29, 2008Assignee: Trexel, Inc.Inventors: Levi A. Kishbaugh, Kevin J. Levesque, Albert H. Guillemette, Liqin Chen, Jingyi Xu, Kelvin T. Okamoto
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Patent number: 7361294Abstract: Injection molding systems and methods useful for making microcellular foamed materials are provided as well as microcellular articles. Pressure drop rate and shear rate are important features in some embodiments, and the invention provides systems for controlling these parameters in an injection molding system. Another aspect involves an injection molding system including a nucleator that is upstream of a pressurized mold. Another aspect involves an extrusion system with the reciprocating screw for forming a single phase solution of non-nucleated blowing agent and polymeric material. Another aspect involves very thin walled microcellular material and very thin walled polymeric material. Another aspect provides a method for producing high weight reductions in very thin-walled parts with surfaces that have no noticeable differences from non-foamed parts.Type: GrantFiled: February 2, 2005Date of Patent: April 22, 2008Assignee: Trexel, Inc.Inventors: David E. Pierick, Jere R. Anderson, Sung Woon Cha, Liqin Chen, James F. Stevenson, Dana E. Laing
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Publication number: 20080090885Abstract: A method for synthesis of losartan 5-carboxylic acid (EXP-3174).Type: ApplicationFiled: January 29, 2007Publication date: April 17, 2008Inventors: Liqin Chen, Jian Li, Yingzhong Shen
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Publication number: 20080050576Abstract: Injection molding systems and methods useful for making microcellular foamed materials are provided as well as microcellular articles. Pressure drop rate and shear rate are important features in some embodiments, and the invention provides systems for controlling these parameters in an injection molding system. Another aspect involves an injection molding system including a nucleator that is upstream of a pressurized mold. Another aspect involves an extrusion system with the reciprocating screw for forming a single phase solution of non-nucleated blowing agent and polymeric material. Another aspect involves very thin walled microcellular material and very thin walled polymeric material. Another aspect provides a method for producing high weight reductions in very thin-walled parts with surfaces that have no noticeable differences from non-foamed parts.Type: ApplicationFiled: August 20, 2007Publication date: February 28, 2008Applicant: Trexel, Inc.Inventors: David Pierick, Jere Anderson, Sung Cha, Liqin Chen, James Stevenson, Dana Laing
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Publication number: 20060035988Abstract: Injection molding systems and methods useful for making microcellular foamed materials are provided as well as microcellular articles. Pressure drop rate and shear rate are important features in some embodiments, and the invention provides systems for controlling these parameters in an injection molding system. Another aspect involves an injection molding system including a nucleator that is upstream of a pressurized mold. Another aspect involves an extrusion system with the reciprocating screw for forming a single phase solution of non-nucleated blowing agent and polymeric material. Another aspect involves very thin walled microcellular material and very thin walled polymeric material. Another aspect provides a method for producing high weight reductions in very thin-walled parts with surfaces that have no noticeable differences from non-foamed parts.Type: ApplicationFiled: February 2, 2005Publication date: February 16, 2006Applicant: Trexel, Inc.Inventors: David Pierick, Jere Anderson, Sung Cha, Liqin Chen, James Stevenson, Dana Laing
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Publication number: 20050163881Abstract: Injection molding systems and methods useful for making microcellular foamed materials are provided as well as microcellular articles. Pressure drop rate and shear rate are important features in some embodiments, and the invention provides systems for controlling these parameters in an injection molding system. Another aspect involves an injection molding system including a nucleator that is upstream of a pressurized mold. Another aspect involves an extrusion system with the reciprocating screw for forming a single phase solution of non-nucleated blowing agent and polymeric material. Another aspect involves very thin walled microcellular material and very thin walled polymeric material. Another aspect provides a method for producing high weight reductions in very thin-walled parts with surfaces that have no noticeable differences from non-foamed parts.Type: ApplicationFiled: February 2, 2005Publication date: July 28, 2005Applicant: Trexel, Inc.Inventors: David Pierick, Jere Anderson, Sung Cha, Liqin Chen, James Stevenson, Dana Laing
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Patent number: 6884823Abstract: Injection molding systems and methods useful for making microcellular foamed materials are provided as well as microcellular articles. Pressure drop rate and shear rate are important features in some embodiments, and the invention provides systems for controlling these parameters in an injection molding system. Another aspect involves an injection molding system including a nucleator that is upstream of a pressurized mold. Another aspect involves an extrusion system with the reciprocating screw for forming a single phase solution of non-nucleated blowing agent and polymeric material. Another aspect involves very thin walled microcellular material and very thin walled polymeric material. Another aspect provides a method for producing high weight reductions in very thin-walled parts with surfaces that have no noticeable differences from non-foamed parts.Type: GrantFiled: June 18, 1999Date of Patent: April 26, 2005Assignee: Trexel, Inc.Inventors: David E. Pierick, Jere R. Anderson, Sung W. Cha, Liqin Chen, James F. Stevenson, Dana E. Laing
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Publication number: 20050042434Abstract: Polymer molding processes, such as injection-molding processes, include use of a viscosity-reducing supercritical fluid additive resulting in less breakage of reinforcing fibers upon introduction into the mold.Type: ApplicationFiled: December 23, 2003Publication date: February 24, 2005Applicant: Trexel, Inc.Inventors: Levi Kishbaugh, Kevin Levesque, Albert Guillemette, Liqin Chen, Jingyi Xu, Kelvin Okamoto
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Publication number: 20040115418Abstract: Foams with low water absorption are provided, along with thermoplastic elastomeric foam materials and methods of forming the same. In some embodiments, the TPE foams have a low water absorption. Microcellular foams are included. Processing conditions (e.g., blowing agent type and content, die geometry, exit melt temperature, among others) may be controlled to produce foams having desirable characteristics, such as low water absorption.Type: ApplicationFiled: August 22, 2003Publication date: June 17, 2004Applicant: Trexel, Inc.Inventors: Jere R. Anderson, Kent G. Blizard, Liqin Chen, Kelvin T. Okamoto
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Publication number: 20040038018Abstract: Foams with low water absorption are provided, along with thermoplastic elastomeric foam materials and methods of forming the same. In some embodiments, the TPE foams have a low water absorption. Microcellular foams are included. Processing conditions (e.g., blowing agent type and content, die geometry, exit melt temperature, among others) may be controlled to produce foams having desirable characteristics, such as low water absorption.Type: ApplicationFiled: August 22, 2002Publication date: February 26, 2004Applicant: Trexel, Inc.Inventors: Jere R. Anderson, Kent G. Blizard, Liqin Chen, Kelvin T. Okamoto
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Publication number: 20010018121Abstract: The present invention provides microcellular articles, as well as methods and apparatuses for producing polymeric foams, and, in particular microcellular material. The methods involve forming a gas blanket within a polymer processing die that prevents contact between the polymer melt and surfaces of the die during extrusion. In one set of embodiments, the gas blanket is provided by gas diffusing out of surfaces of the nucleated polymer material. In other embodiments, the gas blanket is formed by introducing a gas from an external source into the polymer flow channel within the die. The dies, according to the invention, are specially configured to generate and to support the gas blanket. The extruded foams are free of surface defects that, typically, arise from contact between the polymer melt and the die surfaces.Type: ApplicationFiled: March 26, 2001Publication date: August 30, 2001Inventors: Kelvin T. Okamoto, Liqin Chen, Theodore A. Burnham, Richard S. Straff
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Patent number: 5672451Abstract: Disclosed is a migration imaging member which comprises (a) a substrate, (b) a conductive layer comprising indium tin oxide dispersed in a polymeric binder, (c) a siloxane film charge blocking layer comprising a hydrolysis reaction product of a silane of the formula ##STR1## wherein R.sub.1 is an alkylidene group, R.sub.2 and R.sub.3 are each, independent of the other, a hydrogen atom, an alkyl group, a phenyl group, or a poly(ethyleneamino) group, and R.sub.4, R.sub.5, and R.sub.6 are each, independent of the others, alkyl groups, said siloxane having reactive hydroxyl and ammonium groups attached to silicon atoms, and (d) a softenable layer comprising a softenable material and a photosensitive migration marking material. Optionally an antistatic layer comprising indium tin oxide dispersed in a polymeric binder is situated on the surface of the substrate spaced from the softenable layer.Type: GrantFiled: April 11, 1996Date of Patent: September 30, 1997Assignee: Xerox CorporationInventors: Man C. Tam, Liqin Chen, Edward G. Zwartz, Daniel Bihon, Marie-Eve Perron
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Patent number: 5648542Abstract: A process for the preparation of triarylamines which comprises the reaction of an aniline and a haloaromatic component in the presence of a ligand copper catalyst, and wherein the ligand is selected from the group consisting of monodentate tertiary amines and bidentate tertiary amines, and which reaction is accomplished at a temperature of from about 120.degree. C. to about 150.degree. C.Type: GrantFiled: February 29, 1996Date of Patent: July 15, 1997Assignee: Xerox CorporationInventors: H. Bruce Goodbrand, Liqin Chen, Dale S. Renfer
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Patent number: 5563014Abstract: Disclosed is a migration imaging member comprising (a) a substrate, (b) a softenable layer comprising a softenable material and a photosensitive migration marking material, and (c) a transparentizing agent which transparentizes migration marking material in contact therewith contained in at least one layer of the migration imaging member.Type: GrantFiled: May 15, 1995Date of Patent: October 8, 1996Assignee: Xerox CorporationInventors: Shadi L. Malhotra, Liqin Chen, Marie-Eve Perron
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Patent number: 5514505Abstract: Disclosed is a process which comprises (a) providing a migration imaging member comprising (1) a substrate and (2) a softenable layer comprising a softenable material and a photosensitive migration marking material present in the softenable layer as a monolayer of particles situated at or near the surface of the softenable layer spaced from the substrate; (b) uniformly charging the imaging member; (3) imagewise exposing the charged imaging member to activating radiation at a wavelength to which the migration marking material is sensitive; (d) subsequent to step (c), causing the softenable material to soften and enabling a first portion of the migration marking material to migrate through the softenable material toward the substrate in an imagewise pattern while a second portion of the migration marking material remains substantially unmigrated within the softenable layer; and (e) contacting the second portion of the migration marking material with a transparentizing agent which transparentizes migration markiType: GrantFiled: May 15, 1995Date of Patent: May 7, 1996Assignee: Xerox CorporationInventors: William W. Limburg, Joseph Mammino, George Liebermann, Clifford H. Griffiths, Michael M. Shahin, Shadi L. Malhotra, Liqin Chen, Marie-Eve Perron