Abstract: The present invention relates to Tri-Specific Binding Molecules, which are multi-chain polypeptide molecules that possess three Binding Domains and are thus capable of mediating coordinated binding to three epitopes. The Binding Domains may be selected such that the Tri-Specific Binding Molecules are capable of binding to any three different epitopes. Such epitopes may be epitopes of the same antigen or epitopes of two or three different antigens. In a preferred embodiment, one of such epitopes will be capable of binding to CD3, the second of such epitopes will be capable of binding to CD8, and the third of such epitopes will be capable of binding to an epitope of a Disease-Associated Antigen. The invention also provides a novel ROR1-binding antibody, as well as derivatives thereof and uses for such compositions.

Abstract: The present invention relates to a system for effectively identifying pressing line of vehicle and giving an early prompt, comprising an image acquisition module, a lane line extraction module, a distance calculation module and an early-warning judgment module. The image acquisition module acquires front images through an optical camera. The lane line extraction module processes the front images to extract lane lines in each of the images. The distance calculation module calculates a distance between the optical camera and each of left and right lane lines, and calculates the distance between the vehicle and each of the left and right lane lines through the position of the camera in the vehicle and vehicle dimensions. Then, the early-warning judgment module judges whether or not to give a driver an early-warning prompt.