Patents by Inventor Liqing Jin

Liqing Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING HEMATOLOGICAL CANCERS TARGETING THE SIRPALPHA - CD47 INTERACTION
    Publication number: 20240084399
    Abstract: The invention relates to modulating the SIRP?-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRP? polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 14, 2024
    Applicants: UNIVERSITY HEALTH NETWORK, THE HOSPITAL FOR SICK CHILDREN
    Inventors: Jean C.Y. WANG, John DICK, Jayne DANSKA, Liqing JIN, Alexandre THEOCHARIDES, Sujeetha RAJAKUMAR
  • Compositions and methods for treating hematological cancers targeting the SIRP? CD47 interaction
    Patent number: 10907209
    Abstract: The invention relates to modulating the SIRP?-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRP? polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.
    Type: Grant
    Filed: May 14, 2010
    Date of Patent: February 2, 2021
    Assignees: UNIVERSITY HEALTH NETWORK, THE HOSPITAL FOR SICK CHILDREN
    Inventors: Jean C. Y. Wang, John Dick, Jayne Danska, Liqing Jin, Alexandre Theocharides, Sujeetha Rajakumar
  • METHOD OF INHIBITION OF LEUKEMIC STEM CELLS
    Publication number: 20200207861
    Abstract: A method for inhibition of leukemic stem cells expressing IL-3R? (CD123), comprises contacting the cells with an antigen binding molecule comprising a Fc region or a modified Fc region having enhanced Fc effector function, wherein the antigen binding molecule binds selectively to IL-3R? (CD123). The invention includes the treatment of a hematologic cancer condition in a patient by administration to the patient of an effective amount of the antigen binding molecule.
    Type: Application
    Filed: July 19, 2019
    Publication date: July 2, 2020
    Applicants: CSL Limited, University Health Network
    Inventors: John Edgar DICK, Liqing Jin, Gino Luigi VAIRO, David Paul Gearing, Samantha Jane Busfield
  • COMPOSITIONS AND METHODS FOR TREATING HEMATOLOGICAL CANCERS TARGETING THE SIRPALPHA CD47 INTERACTION
    Publication number: 20190093174
    Abstract: The invention relates to modulating the SIRP?-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRP? polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.
    Type: Application
    Filed: August 30, 2018
    Publication date: March 28, 2019
    Inventors: Jean C.Y. Wang, John Dick, Jayne Danska, Liqing Jin, Alexandre Theocharides, Sujeetha Rajakumar
  • METHOD OF INHIBITION OF LEUKEMIC STEM CELLS
    Publication number: 20180079818
    Abstract: A method for inhibition of leukemic stem cells expressing IL-3R? (CD123), comprises contacting the cells with an antigen binding molecule comprising a Fc region or a modified Fc region having enhanced Fc effector function, wherein the antigen binding molecule binds selectively to IL-3R? (CD123). The invention includes the treatment of a hematologic cancer condition in a patient by administration to the patient of an effective amount of the antigen binding molecule.
    Type: Application
    Filed: May 5, 2017
    Publication date: March 22, 2018
    Applicants: CSL Limited, University Health Network
    Inventors: John Edgar Dick, Liqing JIN, Gino Luigi VAIRO, David Paul GEARING, Samantha Jane BUSFIELD
  • METHOD OF INHIBITION OF LEUKEMIC STEM CELLS
    Publication number: 20170029515
    Abstract: A method for inhibition of leukemic stem cells expressing IL-3R? (CD123), comprises contacting the cells with an antigen binding molecule comprising a Fc region or a modified Fc region having enhanced Fc effector function, wherein the antigen binding molecule binds selectively to IL-3R? (CD123). The invention includes the treatment of a hematologic cancer condition in a patient by administration to the patient of an effective amount of the antigen binding molecule.
    Type: Application
    Filed: August 10, 2016
    Publication date: February 2, 2017
    Applicants: CSL Limited, University Health Network
    Inventors: John Edgar Dick, Liqing JIN, Gino Luigi VAIRO, David Paul GEARING, Samantha Jane BUSFIELD
  • METHOD OF INHIBITION OF LEUKEMIC STEM CELLS
    Publication number: 20150152185
    Abstract: A method for inhibition of leukemic stem cells expressing IL-3R.alpha.; (CD 123), comprises contacting the cells with an antigen binding molecule comprising a Fc region or a modified Fc region having enhanced Fc effector function, wherein the antigen binding molecule binds selectively to IL-3R.alpha. (CD123). The invention includes the treatment of a hematologic cancer condition in a patient by administration to the patient of an effective amount of the antigen binding molecule.
    Type: Application
    Filed: November 25, 2014
    Publication date: June 4, 2015
    Applicants: CSL LIMITED, UNIVERSITY HEALTH NETWORK
    Inventors: JOHN EDGAR DICK, LIQING JIN, GINO LUIGI VAIRO, DAVID PAUL GEARING, SAMANTHA JANE BUSFIELD
  • METHOD OF INHIBITION OF LEUKEMIC STEM CELLS
    Publication number: 20130230510
    Abstract: A method for inhibition of leukemic stem cells expressing IL-3R.alpha.; (CD 123), comprises contacting the cells with an antigen binding molecule comprising a Fc region or a modified Fc region having enhanced Fc effector function, wherein the antigen binding molecule binds selectively to IL-3R.alpha. (CD123). The invention includes the treatment of a hematologic cancer condition in a patient by administration to the patient of an effective amount of the antigen binding molecule.
    Type: Application
    Filed: December 4, 2012
    Publication date: September 5, 2013
    Applicants: University Health Network, CSL Limited
    Inventors: John Edgar Dick, Liqing Jin, Gino Luigi Vairo, David Paul Gearing, Samantha Jane Busfield
  • Compositions and Methods for Treating Hematological Cancers Targeting the SIRPA CD47 Interaction
    Publication number: 20120189625
    Abstract: The invention relates to modulating the SIRP?-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRP? polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.
    Type: Application
    Filed: May 14, 2010
    Publication date: July 26, 2012
    Applicant: UNIVERSITY HEALTH NETWORK
    Inventors: Jean C.Y. Wang, John Dick, Jayne Danska, Liqing Jin, Alexandre Theocharides, Sujeetha Rajakumar
  • METHOD OF INHIBITION OF LEUKEMIC STEM CELLS
    Publication number: 20110052574
    Abstract: A method for inhibition of leukemic stem cells expressing IL-3R?; (CD 123), comprises contacting the cells with an antigen binding molecule comprising a Fc region or a modified Fc region having enhanced Fc effector function, wherein the antigen binding molecule binds selectively to IL-3R? (CD123). The invention includes the treatment of a hematologic cancer condition in a patient by administration to the patient of an effective amount of the antigen binding molecule.
    Type: Application
    Filed: December 4, 2008
    Publication date: March 3, 2011
    Inventors: John Edgar Dick, Liqing Jin, Gino Luigi Vairo, David Paul Gearing, Samantha Jane Busfield