Abstract: This disclosure relates to bivalent compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the bivalent compounds, and to methods of use the bivalent compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such bivalent compounds.

Abstract: The present application provides methods, imaging agents and kits for determination of the distribution and expression levels of an immune checkpoint ligand (such as PD-L1 or a PD-L1 like ligand) in an individual having a disease or condition. Anti-PD-L1 antibody agents are also provided.

Abstract: Provided are anti-PD-1 antibodies or fragments thereof. Methods of using the antibodies or fragments thereof for treating and diagnosing diseases such as cancer, infection or immune disorders are also provided.

Abstract: Examples disclosed herein relate to data objects associated with private set intersection (PSI). Some examples disclosed herein may enable identifying a set of server elements and a set of data objects. Each data object of the set of data objects may be associated with at least one server element of the set of server elements. Some examples further enable sending the set of server elements and the set of data objects to a client computing device that has a set of client elements. A private set intersection (PSI) between the set of server elements and the set of client elements may be inaccessible by the client computing device, and a subset of the set of data objects that are associated with the PSI may be accessible by the client computing device.

Abstract: In one example in accordance with the present disclosure, a method may receiving a plaintext to be encrypted. The plaintext may include a first block, a second block and a third block. The method may include generating a preliminary ciphertext based on the first block and the second block and generating, using an encryption key, a first ciphertext using an encryption operation receiving the third block and the preliminary ciphertext as inputs. The method may also include generating, using the encryption key, a first finalized ciphertext using the encryption operation receiving the first block and the first ciphertext as inputs and generating, using the encryption key, a second finalized ciphertext using the encryption operation receiving the second block and the first finalized ciphertext as inputs.

Abstract: The present invention discloses a molecular detection kit for SARS-CoV-2 virus including 2× RT-qPCR mix, upstream primer detF, downstream primer detR, probe, positive control, negative control. The kit has good detection specificity and stability, high sensitivity, and strong anti-interference ability for nucleic acid from the virus host. It has the advantages of simple operation and short time consumption. Moreover, the preparation of positive control is convenient and the cost is low. It can be widely used in early screening of SARS-CoV-2 virus, as well as for epidemic control, scientific research and other fields.

Abstract: Example implementations relate to attestation. For example, in an implementation, a target device attestation request is transmitted to a target device, where the target device attestation request includes an identity-based encryption (IBE) ciphertext and a retrieval index. The ciphertext is a nonce encrypted using a trusted platform module (TPM) public key together with an IBE public key. The TPM public key is retrieved from a TPM of the target device, and the IBE public key is an expected value presumed to be stored at the TPM.

Abstract: The present disclosure relates to generating an identifier, an encrypted value that is an original value encrypted, and a Message Authentication Code (MAC) at a server device, and to generating a message including a message header and a message body, said message header including the identifier and the MAC, and said message body including the encrypted value, and said that the MAC key used to compute the message authentication code is included in the original value to be encrypted, and further relates to transmitting the message to a client device.

Abstract: An example non-transitory computer-readable medium includes instructions that, when executed by a processor, cause the processor to receive a request for data. The instructions also cause the processor to determine a region containing the data based on the metadata. The instructions cause the processor to traverse a tree in the metadata to determine key generation information relating a decryption key for the region to a root key.

Abstract: In some examples, a non-transitory machine readable storage medium has machine readable instructions to cause a computer processor to segment a datastream into a plurality of equal length blocks each of which has a fixed length, separately encrypt each equal length block using a first encryption key, swap a subset of bits of a first encrypted equal length block with a subset of bits of a second encrypted equal length block such that both of the blocks each have a length equal to the fixed length, and separately encrypt each block using a second encryption key.

Abstract: Utilizing error correction (ECC) for secure secret sharing includes computing an encrypted key using a key and a number of random values, computing, based on a first ECC scheme, a key ECC for the encrypted key and the random values, and storing a number of key fragments on a number of storage servers, the number of key fragments includes the encrypted key, the random values, and the key ECC.

Abstract: In an example, memory address encryption is facilitated for transactions between electronic circuits in a memory fabric. An electronic circuit may obtain a transaction integrity key and a transaction encryption key. The electronic circuit may encrypt an address using the transaction encryption key and a compute a truncated message authentication code (MAC) using the transaction integrity key.

Abstract: In an example, transactions are secured between electronic circuits in a memory fabric. An electronic circuit may receive a transaction integrity key. The electronic circuit may compute a truncated message authentication code (MAC) using the received transaction integrity key and attach the truncated MAC to a security message header (SMH) of the transaction.

Abstract: Examples set out herein provide a method comprising using first cryptographic key data specific to a computing device to verify a package of machine readable instructions to run on the computing device. The verified package may be executed to generate a random number using a true random number generator of the computing device, and to store the generated random number. Second cryptographic key data may be generated by a pseudorandom number generator of the computing device based on a seed comprising a combination of the random number as a first seed portion and a second seed portion. A portion of the second cryptographic key data may be sent to a certifying authority. The method may further comprising receiving a certification value based on the sent portion of the second cryptographic key data from the certifying authority and storing the certification value.

Abstract: Example embodiments relate to combining hashes of data blocks. The examples disclosed herein calculate a hash value for each data block in a sequence of data blocks. The hash values are combined into a combined value, where the combined value has the same sequence as the sequence of data blocks. A master hash value is then calculated for the combined value.

Abstract: There is provided an example memory system comprising a plurality of memory modules, each memory module comprising a persistent memory to store root key information and encrypted primary data; a volatile memory to store a working key for encrypting data, the encrypted primary data stored in the persistent memory being encrypted using the working key; and a control unit to provide load and store access to the primary data. The memory system further comprises a working key recovery mechanism to retrieve first root key information from a first module and second root key information from a second module; and compute the working key for a given module based on the retrieved first root key information and the retrieved second root key information.

Abstract: A blockchain includes blocks that each store a hash value computed using a hash function from data of the block. Another hash value is computed for each block using a different hash function, and added to the block within the blockchain. New blocks subsequently added to the blockchain have hash values computed using just the different hash function.

Abstract: Storing and retrieving ciphertext in data storage can include determining a first ciphertext value for a first data chunk to be saved to a client-server data storage system using an encrypted chunk hash value associated with the first data chunk as an initial value, and storing the first data chunk on a server in the client-server data storage system in response to determining that the first ciphertext value is a unique ciphertext value. Also, storing and retrieving ciphertext in data storage can include decrypting a ciphertext value for a second data chunk received from a client in the client-server data storage system and based on an encrypted chunk hash value associated with the second data chunk, and sending the second data chunk to the client in response to determining that the decrypted ciphertext value corresponds to an original data chunk saved to the server by the client.

Abstract: Examples disclosed herein relate to data objects associated with private set intersection (PSI). Some examples disclosed herein may enable identifying a set of server elements and a set of data objects. Each data object of the set of data objects may be associated with at least one server element of the set of server elements. Some examples further enable sending the set of server elements and the set of data objects to a client computing device that has a set of client elements. A private set intersection (PSI) between the set of server elements and the set of client elements may be inaccessible by the client computing device, and a subset of the set of data objects that are associated with the PSI may be accessible by the client computing device.

Abstract: An example non-transitory computer-readable medium includes instructions that, when executed by a processor, cause the processor to receive a request for data. The instructions also cause the processor to determine a region containing the data based on the metadata. The instructions cause the processor to traverse a tree in the metadata to determine key generation information relating a decryption key for the region to a root key.