Abstract: A computer-implemented method of adjusting enteral feeding of a patient by an enteral feeding controller, comprising: computing an estimate of energy expenditure of the patient based on oxygen measurements and carbon dioxide measurements of the patient, computing a target composition and target feeding rate for the enteral feeding according to the computed estimate of energy expenditure, when the target composition and target feeding rate differ from a current enteral feeding composition and feeding rate by a requirement, generating instructions for adjustment, by an enteral feeding controller, of the rate of delivery of the enteral feeding according to the target composition, wherein the receiving the oxygen measurement, receiving the carbon dioxide measurement, and computing the estimate of energy expenditure are performing iteratively for every first time interval, and the generating instructions for adjustment are performed for a second time interval that is larger than the first time interval.

Abstract: An add-on device and method for an Endo-Tracheal Tube (ETT), the add-on device including a lengthy body having a major arc-shaped cross section sized and shaped to tightly fit over an ETT, at least one longitudinal cavity passing along the lengthy body, including a distal suction cavity ending with a suction inlet at a distal end of the lengthy body; and a distal suction outlet channel extending from a proximal end of the lengthy body, the channel is a continuous extension of the distal suction cavity and configured to provide suction to the distal suction cavity. The add-on device senses moisture at a distal end of the add-on device, and in case of detection of excessive wetness, provides suction to the distal end of the device through a cavity passing along the device, the suction is provided via a suction outlet channel extending from a proximal end of the device.

Abstract: There is provided system for monitoring spontaneous breathing of a mechanically ventilated target individual, comprising: a feeding tube for insertion into a distal end of an esophagus of the individual, sensor(s) disposed on the feeding tube at a location such that the sensor(s) is located at the distal end of the esophagus of the individual when the feeding tube is in use, wherein the sensor(s) is positioned for sensing values by contact with the tissue of the esophagus including a lower esophageal sphincter (LES) and/or tissue in proximity to the LES, and code for computing an indication of a frequency band of diaphragm movement of the individual according to an analysis of values sensed by the sensor(s), and for adjustment of parameter(s) of a mechanical ventilator for mechanically ventilating the individual, wherein the instructions for adjustment are computed while the feeding tube is in use.

Abstract: An apparatus for monitoring for accumulation of lung fluid comprises a feeding tube having first electrode(s) positioned thereon for electrical contact with tissue of an esophagus of a target patient including a lower esophageal sphincter (LES) and/or tissue in proximity to the LES, second electrode(s) sized and shaped for contacting skin of the target patient, and a non-transitory memory having stored thereon code instructions for applying alternating current(s) to pair(s) of first and second electrodes, measuring a voltage over the pair(s), and computing an estimate of a change of lung fluid relative to a baseline in lung(s) of the target patient according to the applied alternating current and measured voltage, wherein the applying, the measuring, and the computing the estimate of the change in lung fluid are iteratively executed for monitoring the target patient for accumulation of lung fluid while the feeding tube is in use.

Abstract: There is provided a method comprising: computing a target nutritional goal to reach at an end of a time interval based on a real time energy expenditure of a patient, wherein the target nutritional goal comprises a volume to be delivered (VTBD) by the end of the time interval corresponding to a target amount of energy expenditure of the patient over the time interval, computing a target feeding profile defining a target feeding rate for enteral feeding of the patient for reaching the VTBD by the end of the time interval, continuously monitoring the real time energy expenditure, adapting the target nutritional goal and corresponding VTBD to compute a maximum VTBD to reach at the end of the time interval according to the monitoring, and dynamically adapting the target feeding rate and the corresponding target feeding profile for a remaining portion of the time interval for reaching the maximum VTBD.

Abstract: There is provided a system for measuring impedance at multiple locations within a body of a patient, comprising: an elongated probe sized and shaped for being disposed within a cavity of the body of the patient or in an extracorporeal position, at least one pair of parallel transmission wires disposed along a length of the elongated probe, a plurality of impedance elements, each connected to the at least one pair of parallel transmission wires at a respective spaced apart location along the length of the elongated probe in a ladder arrangement, a transmitter configured for injecting an electrical signal to the at least one pair of parallel transmission wires, a receiver configured for measuring a plurality of reflections of the electrical signal from the plurality of impedance elements, and a processor configured for computing an impedance value for each of the impedance elements according to the measured plurality of reflections.

Abstract: There is provided a urine analysis device for bed side monitoring of a patient, comprising: an inlet sized and shaped for fluid communication with a urine collecting tube that receives urine from a patient; a drip chamber through which the urine flows towards an outlet; at least one sensor that analyzes each drop of urine and estimates a respective volume of each drop; a timing element that measures a reference time for each drop; a program store storing code; and at least one processing unit coupled to the program store for implementing the stored code, the code comprising: code to calculate a urine output flow rate of the urine output flowing through the chamber according to the estimated volume of each drop of the urine and the reference time for each drop; and code to output the urine output flow rate.

Abstract: A computer-implemented method of adjusting enteral feeding of a patient by an enteral feeding controller, comprising: computing an estimate of energy expenditure of the patient based on oxygen measurements and carbon dioxide measurements of the patient, computing a target composition and target feeding rate for the enteral feeding according to the computed estimate of energy expenditure, when the target composition and target feeding rate differ from a current enteral feeding composition and feeding rate by a requirement, generating instructions for adjustment, by an enteral feeding controller, of the rate of delivery of the enteral feeding according to the target composition, wherein the receiving the oxygen measurement, receiving the carbon dioxide measurement, and computing the estimate of energy expenditure are performing iteratively for every first time interval, and the generating instructions for adjustment are performed for a second time interval that is larger than the first time interval.

Abstract: There is provided a system for managing reflux during an enteral feeding, comprising: (i) a non-transitory memory having stored thereon a code for execution by at least one hardware processor of a computing device, the code comprising: code for receiving electrical signals outputted by at least one reflux event sensor disposed within a digestive system of a patient; code for determining a gastric reflux event based on an analysis of the electrical signals; code for outputting instructions to pause enteral feeding of the patient by a feeding controller that regulates enteral feeding of the patient using an enteral feeding tube positioned within the digestive system of the patient; and (ii) an evacuation controller that directs back-flow of digestive contents from the digestive system of the patient to an external evacuation reservoir through an evacuation tube.

Abstract: A computer-implemented method of treating a patient's and automated enteral feeding, comprising: monitoring a plurality of reflux-related parameters and at least one reflux event while the patient is automatically enterally fed by an enteral feeding controller according to a baseline feeding profile including a target nutritional goal, training a classifier component of a model for predicting likelihood of a future reflux event according to an input of scheduled and/or predicted plurality of reflux-related parameters, the classifier trained according to computed correlations between the plurality of reflux-related parameters and the at least one reflux event, feeding scheduled and/or predicted reflux-related parameters into the trained classifier component of the model for outputting risk of likelihood of a future reflux event, and computing, by the model, an adjustment to the baseline feeding profile for reducing likelihood of the future reflux event and for meeting the target nutritional goal.

Abstract: A naso/orogastric device having backflow blocking means and comprises a naso/orogastric tube sized and shaped for being disposed within the esophagus so that at least a distal end thereof being placed in the stomach lumen of a patient, at least one elastic esophageal body, positioned along the naso/orogastric tube, having a pressure dependent volume, at least one esophageal sensor that detects fluid around at least one segment of the naso/orogastric tube, and a pressure regulator that regulates a pressure within the elastic esophageal body according to the detection.

Abstract: There is provided a urine analysis device for bed side monitoring of a patient, comprising: an inlet sized and shaped for fluid communication with a urine collecting tube that receives urine from a patient; a drip chamber through which the urine flows towards an outlet; at least one sensor that analyzes each drop of urine and estimates a respective volume of each drop; a timing element that measures a reference time for each drop; a program store storing code; and at least one processing unit coupled to the program store for implementing the stored code, the code comprising: code to calculate a urine output flow rate of the urine output flowing through the chamber according to the estimated volume of each drop of the urine and the reference time for each drop; and code to output the urine output flow rate.

Abstract: A compound sheath comprising: an endoscopic channel arranged for accepting an elongated endoscopic imaging device; a parallel use channel arranged for accepting a catheter-based tool, and a multi-channel hub that couples to the proximal end of the parallel use channel comprising: a rinse port that couples to a fluid reservoir device that injects fluid; a withdrawal port that couples to a vacuum forming device that removes fluid; a tool port for passing a catheter-based tool; wherein the multi-channel hub establishes a fluid channel for fluid communication between the parallel use channel and the rinse port or the withdrawal port, and a mechanical channel for passing therethrough a catheter-based tool between the parallel use channel and the tool port such that fluid from the rinse port or the withdrawal port and the catheter-based tool of the tool port are simultaneously passing all along the parallel use channel.

Abstract: A medical pump, comprising: a fluid housing having a plurality of intake openings, sealed by at least one intake valve, and an outlet opening sealed by an outlet valve; a piston which is sealing the fluid housing and connected to a drive mechanism, the drive mechanism pulls the piston to draw fluid from one of the plurality of intake openings and pushes the piston to discharge the fluid into the outlet opening; and a selecting valve enclosing at least two tubes, each providing fluid to one of the plurality of intake openings, wherein the selecting valve closes one of the at least two tubes while opening another of the at least two tubes.

Abstract: A naso/orogastric device having backflow blocking means and comprises a naso/orogastric tube sized and shaped for being disposed within the esophagus so that at least a distal end thereof being placed in the stomach lumen of a patient, at least one elastic esophageal body, positioned along the naso/orogastric tube, having a pressure dependent volume, at least one esophageal sensor that detects fluid around at least one segment of the naso/orogastric tube, and a pressure regulator that regulates a pressure within the elastic esophageal body according to the detection.

Abstract: An add-on device and method for an Endo-Tracheal Tube (ETT), the add-on device including a lengthy body having a major arc-shaped cross section sized and shaped to tightly fit over an ETT, at least one longitudinal cavity passing along the lengthy body, including a distal suction cavity ending with a suction inlet at a distal end of the lengthy body; and a distal suction outlet channel extending from a proximal end of the lengthy body, the channel is a continuous extension of the distal suction cavity and configured to provide suction to the distal suction cavity. The add-on device senses moisture at a distal end of the add-on device, and in case of detection of excessive wetness, provides suction to the distal end of the device through a cavity passing along the device, the suction is provided via a suction outlet channel extending from a proximal end of the device.

Abstract: A catheter, comprising: a flexible tubular member having at least one lumen therethrough and a proximal end and a distal end; a plurality of conductive cables extending through at least one of the at least one lumen; and at least one electrically operated component, attached at the distal end and powered by at least one electrical current driven on at least one of the plurality of conductive cables. Some of the plurality of conductive cables are attached to the distal end such that the flexible tubular member is deformed by exerting at the proximal end a tensile force on one of the some of the plurality of conductive cables and a compressive force on another of the some of the plurality of conductive cables, while the at least one electrical current is driven on the some of the plurality of conductive cables.

Abstract: An apparatus for monitoring for accumulation of lung fluid comprises a feeding tube having first electrode(s) positioned thereon for electrical contact with tissue of an esophagus of a target patient including a lower esophageal sphincter (LES) and/or tissue in proximity to the LES, second electrode(s) sized and shaped for contacting skin of the target patient, and a non-transitory memory having stored thereon code instructions for applying alternating current(s) to pair(s) of first and second electrodes, measuring a voltage over the pair(s), and computing an estimate of a change of lung fluid relative to a baseline in lung(s) of the target patient according to the applied alternating current and measured voltage, wherein the applying, the measuring, and the computing the estimate of the change in lung fluid are iteratively executed for monitoring the target patient for accumulation of lung fluid while the feeding tube is in use.

Abstract: There is provided a system for managing reflux during an enteral feeding, comprising: (i) a non-transitory memory having stored thereon a code for execution by at least one hardware processor of a computing device, the code comprising: code for receiving electrical signals outputted by at least one reflux event sensor disposed within a digestive system of a patient; code for determining a gastric reflux event based on an analysis of the electrical signals; code for outputting instructions to pause enteral feeding of the patient by a feeding controller that regulates enteral feeding of the patient using an enteral feeding tube positioned within the digestive system of the patient; and (ii) an evacuation controller that directs back-flow of digestive contents from the digestive system of the patient to an external evacuation reservoir through an evacuation tube.

Abstract: An add-on device and method for an Endo-Tracheal Tube (ETT), the add-on device including a lengthy body having a major arc-shaped cross section sized and shaped to tightly fit over an ETT, at least one longitudinal cavity passing along the lengthy body, including a distal suction cavity ending with a suction inlet at a distal end of the lengthy body; and a distal suction outlet channel extending from a proximal end of the lengthy body, the channel is a continuous extension of the distal suction cavity and configured to provide suction to the distal suction cavity. The add-on device senses moisture at a distal end of the add-on device, and in case of detection of excessive wetness, provides suction to the distal end of the device through a cavity passing along the device, the suction is provided via a suction outlet channel extending from a proximal end of the device.