Patents by Inventor Lisa A. Collins-Racie

Lisa A. Collins-Racie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT LUBRICIN MOLECULES AND USES THEREOF
    Publication number: 20150343019
    Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided.
    Type: Application
    Filed: February 5, 2015
    Publication date: December 3, 2015
    Inventors: Carl Ralph FLANNERY, Christopher John Corcoran, Bethany Annis Freeman, Lisa A. Collins-Racie
  • Polynucleotides encoding recombinant lubricin molecules and uses thereof
    Patent number: 8987205
    Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: March 24, 2015
    Assignee: Wyeth LLC
    Inventors: Carl Ralph Flannery, Christopher John Corcoran, Bethany Annis Freeman, Lisa A. Collins-Racie
  • Polynucleotides encoding recombinant lubricin molecules and uses thereof
    Patent number: 8420793
    Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: April 16, 2013
    Assignee: Pfizer Inc.
    Inventors: Carl R. Flannery, Christopher J. Corcoran, Bethany A. Freeman, Lisa A. Collins-Racie
  • POLYNUCLEOTIDES ENCODING RECOMBINANT LUBRICIN MOLECULES AND USES THEREOF
    Publication number: 20110189731
    Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided.
    Type: Application
    Filed: February 25, 2011
    Publication date: August 4, 2011
    Inventors: CARL RALPH FLANNERY, CHRISTOPHER JOHN CORCORAN, BETHANY ANNIS FREEMAN, LISA A. COLLINS-RACIE
  • Recombinant lubricin molecules and uses thereof
    Patent number: 7897571
    Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: March 1, 2011
    Assignee: Wyeth LLC
    Inventors: Carl Ralph Flannery, Christopher John Corcoran, Bethany Annis Freeman, Lisa A. Collins-Racie
  • Recombinant lubricin molecules and uses thereof
    Patent number: 7893029
    Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: February 22, 2011
    Assignee: Wyeth LLC
    Inventors: Carl Ralph Flannery, Christopher John Corcoran, Bethany Annis Freeman, Lisa A. Collins-Racie
  • Recombinant Lubricin Molecules and Uses Thereof
    Publication number: 20100080848
    Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided.
    Type: Application
    Filed: November 23, 2009
    Publication date: April 1, 2010
    Applicant: WYETH
    Inventors: Carl Ralph Flannery, Christopher John Corcoran, Bethany Annis Freeman, Lisa A. Collins-Racie
  • RECOMBINANT LUBRICIN MOLECULES AND USES THEREOF
    Publication number: 20100074935
    Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided.
    Type: Application
    Filed: November 19, 2009
    Publication date: March 25, 2010
    Applicant: Wyeth
    Inventors: Carl Ralph Flannery, Christopher John Corcoran, Bethany Annis Freeman, Lisa A. Collins-Racie
  • PROTEIN KINASE C ZETA AS A DRUG TARGET FOR ARTHRITIS AND OTHER INFLAMMATORY DISEASES
    Publication number: 20100062448
    Abstract: The present invention is based on the discovery that ?PKC expression is increased in the tissues of arthritis patients as compared to normal individuals. Accordingly, the present invention provides methods of diagnosing, prognosing, and monitoring the course of arthritis in a patient based on increased ?PKC gene expression in arthritic tissue. The present invention further provides compounds that inhibit the expression of ?PKC for use as remedies in the treatment of arthritis, including, but not limited to, inhibitory polynucleotides and polypeptides, small molecules, and peptide inhibitors. In addition, the present invention provides pharmaceutical formulations and routes of administration for such remedies, as well as methods for assessing their efficacy.
    Type: Application
    Filed: November 11, 2009
    Publication date: March 11, 2010
    Applicant: WYETH
    Inventors: Edward R. LaVallie, Lisa A. Collins-Racie, Maya Arai
  • Recombinant lubricin molecules and uses thereof
    Patent number: 7642236
    Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura are provided.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: January 5, 2010
    Assignee: Wyeth
    Inventors: Carl Ralph Flannery, Christopher John Corcoran, Bethany Annis Freeman, Lisa A. Collins-Racie
  • Protein kinase C zeta as a drug target for arthritis and other inflammatory diseases
    Patent number: 7638482
    Abstract: The present invention is based on the discovery that ?PKC expression is increased in the tissues of arthritis patients as compared to normal individuals. Accordingly, the present invention provides methods of diagnosing, prognosing, and monitoring the course of arthritis in a patient based on increased ?PKC gene expression in arthritic tissue. The present invention further provides compounds that inhibit the expression of ?PKC for use as remedies in the treatment of arthritis, including, but not limited to, inhibitory polynucleotides and polypeptides, small molecules, and peptide inhibitors. In addition, the present invention provides pharmaceutical formulations and routes of administration for such remedies, as well as methods for assessing their efficacy.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: December 29, 2009
    Assignee: Wyeth
    Inventors: Edward R. LaVallie, Lisa A. Collins-Racie, Maya Arai
  • Aggrecanase structure
    Patent number: 7625731
    Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.
    Type: Grant
    Filed: August 24, 2006
    Date of Patent: December 1, 2009
    Assignee: Wyeth
    Inventors: Lydia Mosyak, Thomas Saltmarsh Rush, III, Stephane Hubert Olland, Edward R. LaVallie, Lisa A. Collins-Racie, Christopher John Corcoran, Stewart Andrews Mackie
  • Aggrecanase structure
    Patent number: 7615363
    Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.
    Type: Grant
    Filed: August 24, 2006
    Date of Patent: November 10, 2009
    Assignee: Wyeth
    Inventors: Lidia Mosyak, Thomas Saltmarsh Rush, III, Xiaotian Zhong, Thomas E. McDonagh, Katy E. Georgiadis, Phaik-Eng Sum, Edward R. LaVallie, Lisa A. Collins-Racie, Christopher John Corcoran, Ravindra Kumar, Tracy Hebert, Stephane Hubert Olland, Stewart Andrews Mackie
  • USE OF RXR AGONISTS FOR THE TREATMENT OF OSTEOARTHRITIS
    Publication number: 20090209601
    Abstract: Disclosed herein are methods of preventing and treating osteoarthritis through the use of RXR agonists.
    Type: Application
    Filed: February 11, 2009
    Publication date: August 20, 2009
    Applicant: Wyeth
    Inventors: Sunil Nagpal, Zhiyong Yang, Elisabeth Morris, Edward R. Lavallie, Lisa A. Collins-Racie
  • EXPRESSION OF ORPHAN GPR64 IN INFLAMMATORY DISEASES
    Publication number: 20090202474
    Abstract: Methods of screening for agents for treating inflammatory diseases are provided. The methods involve screening for agents that modulate the activity or expression of GPR64, which has been discovered herein to play a role in inflammatory diseases. Methods for treating an inflammatory disease, as well as methods of modulating the activity or expression of GPR64, methods of screening for an inflammatory disease in a subject, pharmaceutical compositions, a nucleic acid variant, and antibodies are also provided.
    Type: Application
    Filed: November 19, 2008
    Publication date: August 13, 2009
    Applicant: WYETH
    Inventors: Priya CHOCKALINGAM, Manas K. MAJUMDAR, Debra D. PITTMAN, Julia BILLIARD, Edward Roland LAVALLIE, Jeffrey L. FELDMAN, Lisa COLLINS-RACIE, Vishnuvardhan DAESETY, Robert MORAN, Elisabeth A. MORRIS, Paul YAWORSKY
  • Use of LXR agonists for the treatment of osteoarthritis
    Publication number: 20090012053
    Abstract: Disclosed herein are methods of preventing and treating osteoarthritis through the use of LXR agonists.
    Type: Application
    Filed: September 18, 2007
    Publication date: January 8, 2009
    Applicant: Wyeth
    Inventors: Sunil Nagpal, Zhiyong Yang, Elisabeth Morris, Edward R. LaVallie, Lisa A. Collins-Racie
  • Secreted proteins and polynucleotides encoding them
    Publication number: 20080139452
    Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.
    Type: Application
    Filed: December 13, 2007
    Publication date: June 12, 2008
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Kenneth Jacobs, John M. McCoy, Edward R. LaVallie, Lisa A. Collins-Racie, David Merberg, Michael J. Agostino, Robert Steininger, Vikki Spaulding, Gordon G. Wong, Hilary F. Clark, Kim Fechtel, Cheryl Evans, Maurice Treacy
  • Secreted proteins and polynucleotides encoding them
    Patent number: 7344861
    Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.
    Type: Grant
    Filed: April 3, 2006
    Date of Patent: March 18, 2008
    Assignee: Ono Pharmaceutical Co., Ltd.
    Inventors: Kenneth Jacobs, John M. McCoy, Edward R. LaVallie, Lisa A. Collins-Racie, David Merberg, Michael J. Agostino, Robert J. Steininger, II, Vikki Spaulding, Gordon G. Wong, Hilary F. Clark, Kim Fechtel, Cheryl Evans, Maurice Treacy
  • Recombiant lubricin molecules and uses thereof
    Publication number: 20070191268
    Abstract: Recombinant lubricin molecules and uses thereof Novel recombinant lubricin molecules and their uses as lubricants anti-adhesive agents and/or intra-articular supplements for, e.g., synvial joints, meniscus, tendon, peritoneum, pericardium and pleura are provided.
    Type: Application
    Filed: August 13, 2004
    Publication date: August 16, 2007
    Applicant: WYETH
    Inventors: Carl Flannery, Christopher Corcoran, Bethany Freeman, Lisa Collins-Racie
  • AGGRECANASE STRUCTURE
    Publication number: 20070178574
    Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.
    Type: Application
    Filed: August 24, 2006
    Publication date: August 2, 2007
    Applicant: WYETH
    Inventors: Lydia Mosyak, Thomas Rush, Xiaotian Zhong, Thomas McDonagh, Katy Georgiadis, Phaik-Eng Sum, Edward LaVallie, Lisa Collins-Racie, Christopher Corcoran, Ravindra Kumar, Tracy Hebert, Stephane Olland, Stewart Mackie