Abstract: Systems and methods for treating a patient for a medical condition using an interactive treatment pathway interface associated with the medical condition include receiving, through an interface, patient data representing a medical status of a patient. Treatment pathway data representing a sequence of actions for a particular treatment or diagnosis of a medical condition of the patient are retrieved. The interface guides the particular treatment or diagnosis of the medical condition by a traversal of the treatment pathway. A data trace is generated from additional patient data received during the traversal. The represents the instance of the particular treatment or diagnosis of the medical condition of the patient. The data are used to affect the particular treatment or diagnosis for the medical condition to the patient and inform machine learning operations for diagnosis or treatment of the medical condition.