Patents by Inventor Lisa Diane Reiss

Lisa Diane Reiss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solubility tags for the expression and purification of bioactive peptides
    Patent number: 7794979
    Abstract: Peptide tags, referred to here as inclusion body tags, are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a product that is insoluble and contained within inclusion bodies in the cell and/or cell lysate. The inclusion bodies may then be purified and the protein of interest may be isolated after cleavage from the inclusion body tag.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: September 14, 2010
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Qiong Cheng, Linda Jane Decarolis, Stephen R. Fahnestock, Tanja Maria Gruber, Lisa Diane Reiss, Pierre E. Rouviere
  • SOLUBILITY TAGS FOR THE EXPRESSION AND PURIFICATION OF BIOACTIVE PEPTIDES
    Publication number: 20100136621
    Abstract: Peptide tags, referred to here as inclusion body tags, are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a product that is insoluble and contained within inclusion bodies in the cell and/or cell lysate. The inclusion bodies may then be purified and the protein of interest may be isolated after cleavage from the inclusion body tag.
    Type: Application
    Filed: January 25, 2010
    Publication date: June 3, 2010
    Applicant: E.I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Qiong Cheng, Linda Jane Decarolis, Stephen R. Fahnestock, Tanja Maria Gruber, Lisa Diane Reiss, Pierre E. Rouviere
  • Solubility tags for the expression and purification of bioactive peptides
    Patent number: 7678883
    Abstract: Peptide tags, referred to here as inclusion body tags, are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a product that is insoluble and contained within inclusion bodies in the cell and/or cell lysate. The inclusion bodies may then be purified and the protein of interest may be isolated after cleavage from the inclusion body tag.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: March 16, 2010
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Qiong Cheng, Linda Jane Decarolis, Stephen R. Fahnestock, Tanja Maria Gruber, Lisa Diane Reiss, Pierre E. Rouviere
  • SOLUBILITY TAGS FOR THE EXPRESSION AND PURIFICATION OF BIOACTIVE PEPTIDES
    Publication number: 20090029412
    Abstract: Peptide tags, referred to here as inclusion body tags, are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a product that is insoluble and contained within inclusion bodies in the cell and/or cell lysate. The inclusion bodies may then be purified and the protein of interest may be isolated after cleavage from the inclusion body tag.
    Type: Application
    Filed: July 25, 2007
    Publication date: January 29, 2009
    Inventors: Qiong Cheng, Linda Jane Decarolis, Stephen R. Fahnestock, Tanja Maria Gruber, Lisa Diane Reiss