Patents by Inventor Lisa Flanagan Monuki

Lisa Flanagan Monuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidic device for cell and particle separation
    Patent number: 7964078
    Abstract: A microfluidic separation device includes a microchannel formed in a substrate and being defined at least by a bottom surface, a first side wall, and second side wall. Fluid containing particles or cells is flowed through the microchannel from an upstream end to a downstream end. The downstream end terminates in a plurality of branch channels. A plurality of vertically-oriented electrodes are disposed on the first wall and on the second wall opposite to the first wall. A voltage source is connected to the plurality of opposing electrodes to drive the electrodes. The opposing, vertically-oriented electrodes may be used to focus a heterogeneous population of particles or cells for subsequent downstream separation via additional electrodes placed on one of the side walls. Alternatively, the opposing, vertically-oriented electrodes may be used to spatially separate a heterogeneous population of particles or cells for later collection in one or more of the branch channels.
    Type: Grant
    Filed: February 2, 2007
    Date of Patent: June 21, 2011
    Assignee: The Regents of the University of California
    Inventors: Abraham P. Lee, Lisen Wang, Lisa Flanagan Monuki, Edwin S. Monuki, Svyatoslav A. Marchenko
  • MICROFLUIDIC DEVICE FOR CELL AND PARTICLE SEPARATION
    Publication number: 20070125941
    Abstract: A microfluidic separation device includes a microchannel formed in a substrate and being defined at least by a bottom surface, a first side wall, and second side wall. Fluid containing particles or cells is flowed through the microchannel from an upstream end to a downstream end. The downstream end terminates in a plurality of branch channels. A plurality of vertically-oriented electrodes are disposed on the first wall and on the second wall opposite to the first wall. A voltage source is connected to the plurality of opposing electrodes to drive the electrodes. The opposing, vertically-oriented electrodes may be used to focus a heterogeneous population of particles or cells for subsequent downstream separation via additional electrodes placed on one of the side walls. Alternatively, the opposing, vertically-oriented electrodes may be used to spatially separate a heterogeneous population of particles or cells for later collection in one or more of the branch channels.
    Type: Application
    Filed: February 2, 2007
    Publication date: June 7, 2007
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Abraham Lee, Lisen Wang, Lisa Flanagan Monuki, Edwin Monuki, Svyatoslav Marchenko