Patents by Inventor Lisa Frost

Lisa Frost has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production Processes of S- and O-Diacylated Gamma-Glutamyl-Cysteamine Prodrugs
    Publication number: 20220106267
    Abstract: Methods are provided for the synthesis of a compound of formula (X). R2 is selected from —H, —C1-C4-alkyl, —C2-C4-alkenyl and C1-C4-aryl; R3 is selected from —C(O)H and —C(O)C1-C4-alkyl; and A is a pharmaceutically acceptable anion (e.g. a halide). Also provided are intermediate compounds formed during the synthesis.
    Type: Application
    Filed: February 14, 2020
    Publication date: April 7, 2022
    Inventors: Rosaleen Joy Anderson, Lisa Frost, Neil Barnwell, Matthew Levick, Ivan Hales, Michael Dunn
  • N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors
    Publication number: 20070299107
    Abstract: The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives.
    Type: Application
    Filed: March 16, 2007
    Publication date: December 27, 2007
    Inventors: John Toscano, Frederick Brookfield, Andrew Cohen, Stephen Courtney, Lisa Frost, Vincent Kalish