Patents by Inventor Lisa HARMS

Lisa HARMS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of virus-receptive pluripotent stem cell (PSC)-derived hepatocytes
    Patent number: 10093903
    Abstract: The present disclosure provides methods for maturing hepatocytes comprising culturing with cyclic adenosine monophosphate and a Janus kinase inhibitor. There is also provided a method for screening inhibitors of hepatitis B virus infection and/or replication.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: October 9, 2018
    Assignee: FUJIFILM Cellular Dynamics, Inc.
    Inventors: Christian Kannemeier, Elisabeth Enghofer, Lisa Harms
  • Generation of keratinocytes from pluripotent stem cells and maintenance of keratinocyte cultures
    Patent number: 10047341
    Abstract: Provided herein are methods for the generation of functional keratinocyte stem cells that are differentiated directly from human ESCs/iPSCs in a chemically defined serum-free cell culture system, as well as cells derived therefrom and methods of use thereof. Also provided are methods for culturing primary keratinocytes.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: August 14, 2018
    Assignee: FUJIFILM Cellular Dynamics, Inc.
    Inventors: Junying Yu, Ying Zhang, Lisa Harms
  • PRODUCTION OF VIRUS-RECEPTIVE PLURIPOTENT STEM CELL (PSC)-DERIVED HEPATOCYTES
    Publication number: 20170107485
    Abstract: The present disclosure provides methods for maturing hepatocytes comprising culturing with cyclic adenosine monophosphate and a Janus kinase inhibitor. There is also provided a method for screening inhibitors of hepatitis B virus infection and/or replication.
    Type: Application
    Filed: October 19, 2016
    Publication date: April 20, 2017
    Inventors: Christian KANNEMEIER, Elisabeth ENGHOFER, Lisa HARMS
  • GENERATION OF KERATINOCYTES FROM PLURIPOTENT STEM CELLS AND MAINTENANCE OF KERATINOCYTE CULTURES
    Publication number: 20160102289
    Abstract: Provided herein are methods for the generation of functional keratinocyte stem cells that are differentiated directly from human ESCs/iPSCs in a chemically defined serum-free cell culture system, as well as cells derived therefrom and methods of use thereof. Also provided are methods for culturing primary keratinocytes.
    Type: Application
    Filed: October 13, 2015
    Publication date: April 14, 2016
    Applicant: CELLULAR DYNAMICS INTERNATIONAL, INC.
    Inventors: Junying YU, Ying ZHANG, Lisa HARMS