Patents by Inventor Lisa-Jo Ann CLARIZIA

Lisa-Jo Ann CLARIZIA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for raising antibodies
    Patent number: 11603400
    Abstract: The present invention generally relates to methods of generating antibodies against a species of pathogen that involve identifying the pathogen that is most genetically representative of member of pathogen species and using the identified pathogen to generate an antibody.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: March 14, 2023
    Assignee: DNAE Group Holdings Limited
    Inventors: Colin Dykes, Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Meghan E. Norvell
  • Isolating a target analyte from a body fluid
    Patent number: 11448646
    Abstract: The invention generally relates to using magnetic particles and magnets to isolate a target analyte from a body fluid sample. In certain embodiments, methods of the invention involve introducing magnetic particles including a target-specific binding moiety to a body fluid sample in order to create a mixture, incubating the mixture to allow the particles to bind to a target, applying a magnetic field to capture target/magnetic particle complexes on a surface, and washing with a wash solution that reduces particle aggregation, thereby isolating target/magnetic particle complexes.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: September 20, 2022
    Assignee: DNAE Group Holdings Limited
    Inventors: Lisa-Jo Ann Clarizia, Eddie W. Adams, Sergey A. Dryga
  • Analyzing bacteria without culturing
    Patent number: 10677789
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: June 9, 2020
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • Methods for isolating a target analyte from a heterogenous sample
    Patent number: 10416155
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: September 17, 2019
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • METHODS FOR RAISING ANTIBODIES
    Publication number: 20190153075
    Abstract: The present invention generally relates to methods of generating antibodies against a species of pathogen that involve identifying the pathogen that is most genetically representative of member of pathogen species and using the identified pathogen to generate an antibody.
    Type: Application
    Filed: June 18, 2018
    Publication date: May 23, 2019
    Inventors: Colin W. Dykes, Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Meghan Norvell
  • METHODS FOR ISOLATING A TARGET ANALYTE FROM A HETEROGENOUS SAMPLE
    Publication number: 20180252709
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Application
    Filed: May 2, 2018
    Publication date: September 6, 2018
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Methods for raising antibodies
    Patent number: 10000557
    Abstract: The present invention generally relates to methods of generating antibodies against a species of pathogen that involve identifying the pathogen that is most genetically representative of member of pathogen species and using the identified pathogen to generate an antibody.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: June 19, 2018
    Assignee: DNAE Group Holdings Limited
    Inventors: Colin Dykes, Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Meghan Norvell
  • ISOLATING A TARGET ANALYTE FROM A BODY FLUID
    Publication number: 20180149642
    Abstract: The invention generally relates to using magnetic particles and magnets to isolate a target analyte from a body fluid sample. In certain embodiments, methods of the invention involve introducing magnetic particles including a target-specific binding moiety to a body fluid sample in order to create a mixture, incubating the mixture to allow the particles to bind to a target, applying a magnetic field to capture target/magnetic particle complexes on a surface, and washing with a wash solution that reduces particle aggregation, thereby isolating target/magnetic particle complexes.
    Type: Application
    Filed: January 12, 2018
    Publication date: May 31, 2018
    Inventors: Lisa-Jo Ann Clarizia, Eddie W. Adams, Sergey A. Dryga
  • METHODS FOR ISOLATING A TARGET ANALYTE FROM A HETEROGENOUS SAMPLE
    Publication number: 20180143189
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Application
    Filed: January 5, 2018
    Publication date: May 24, 2018
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • ANALYZING BACTERIA WITHOUT CULTURING
    Publication number: 20180136205
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Application
    Filed: January 10, 2018
    Publication date: May 17, 2018
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • Methods for isolating a target analyte from a heterogenous sample
    Patent number: 9970931
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: May 15, 2018
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Analyzing bacteria without culturing
    Patent number: 9869671
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: January 16, 2018
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • Methods for isolating a target analyte from a heterogenous sample
    Patent number: 9863940
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: January 9, 2018
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • METHODS FOR ISOLATING A TARGET ANALYTE FROM A HETEROGENOUS SAMPLE
    Publication number: 20170261501
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Application
    Filed: May 30, 2017
    Publication date: September 14, 2017
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • ANALYZING BACTERIA WITHOUT CULTURING
    Publication number: 20170227535
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Application
    Filed: April 25, 2017
    Publication date: August 10, 2017
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • Methods for isolating a target analyte from a heterogeneous sample
    Patent number: 9696302
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: July 4, 2017
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Analyzing bacteria without culturing
    Patent number: 9671395
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: June 6, 2017
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • EXTRACTING LOW CONCENTRATIONS OF BACTERIA FROM A SAMPLE
    Publication number: 20170145406
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a bacterium from the sample, in which the assay isolates as low as about 1 CFU/ml of bacteria in the sample.
    Type: Application
    Filed: February 6, 2017
    Publication date: May 25, 2017
    Inventors: Victor C. Esch, Sergey A. Dryga, Lisa-Jo Ann Clarizia
  • METHODS FOR ISOLATING A TARGET ANALYTE FROM A HETEROGENOUS SAMPLE
    Publication number: 20170038374
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Application
    Filed: October 24, 2016
    Publication date: February 9, 2017
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Extracting low concentrations of bacteria from a sample
    Patent number: 9562896
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a bacterium from the sample, in which the assay isolates as low as about 1 CFU/ml of bacteria in the sample.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: February 7, 2017
    Assignee: DNAE Group Holdings Limited
    Inventors: Victor C. Esch, Sergey A. Dryga, Lisa-Jo Ann Clarizia