Patents by Inventor Lisa K. Sadzewicz

Lisa K. Sadzewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cancer susceptibility mutations of BRCA1
    Patent number: 6083698
    Abstract: New mutations have been found in the BRCA1 gene. The mutations are located at nucleotide numbers 421-2, 815, 903, 926, 1506, 2034, 2428, 3888, 3904, 4164, 4643, 5053, 5150, 5210, or 5396+40 of the gene sequence of BRCA1. A process for identifying a sequence variation in a BRCA1 polynucleotide sequence is disclosed. The identification process includes allele specific sequence-based assays of known sequence variations. The methods can be used for efficient, and accurate detection of a mutation in a test BRCA1 gene sample.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: July 4, 2000
    Assignee: Oncormed, Inc.
    Inventors: Sheri Jon Olson, Tracy Staton Angelly, Tammy Lawrence, Jennifer Lee Lescallett, Patricia Davis Murphy, Antonette Preisinger Allen, Denise Bernadette Thurber, Marga Belle White, Bin Zeng, Lisa K. Sadzewicz
  • Susceptibility mutation for breast and ovarian cancer
    Patent number: 5756294
    Abstract: A new mutation has been found in the BRCA1 gene. The mutation is a two base pair deletion at nucleotides 3888 and 3889 of the published cDNA sequence of BRCA1 (GENBANK ACCESSION NO:U14680). The invention provides a method for diagnosing persons at risk of developing breast or ovarian cancer. The invention also provides a further tool with which to characterize tumors.
    Type: Grant
    Filed: September 25, 1995
    Date of Patent: May 26, 1998
    Assignee: OncorMed, Inc.
    Inventors: Marga B. White, Lisa K. Sadzewicz